Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL032C
Length:
597
Number of sequences:
5887
Description:
YKL032C IXR1 SGDID:S000001515, Chr XI from 381858-380065, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241B7SBD2    577   TOX3_RAT TOX high mobility group box family m...720.045     40.4     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0034056; F:estrogen response element binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
242Q04890    314   SOX12_MOUSE Transcription factor SOX-12 OS=Mu...520.046     40     37     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032993; C:protein-DNA complex; IDA:UniProtKB.
GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.
GO:0065004; P:protein-DNA complex assembly; IDA:UniProtKB.::GO:0021510; P:spinal cord development; IDA:UniProtKB.
243Q8IDX6    3130   RBP2A_PLAF7 Reticulocyte-binding protein 2 ho...674     34.3     25     67GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.
244O04235    642   SSRP1_VICFA FACT complex subunit SSRP1 OS=Vic...623.5     34.3     24     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
245P51501    227   SRY_CALJA Sex-determining region Y protein OS...492.5     34.3     35     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
246Q9W7R5    280   SOX21_CHICK Transcription factor SOX-21 OS=Ga...520.054     39.7     37     65GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
247O15405    576   TOX3_HUMAN TOX high mobility group box family...688.8     33.1     25     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0034056; F:estrogen response element binding; IDA:UniProtKB.::GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
248P43680    377   SOX18_MOUSE Transcription factor SOX-18 OS=Mu...513.3     34.3     29     63GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0048469; P:cell maturation; IDA:MGI.::GO:0035050; P:embryonic heart tube development; IGI:MGI.::GO:0060956; P:endocardial cell differentiation; IGI:MGI.::GO:0060214; P:endocardium formation; IGI:MGI.::GO:0001942; P:hair follicle development; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001946; P:lymphangiogenesis; IMP:MGI.::GO:0060836; P:lymphatic endothelial cell differentiation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0072091; P:regulation of stem cell proliferation; IDA:MGI.::GO:0048866; P:stem cell fate specification; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
249P40646    380   SOX7_MOUSE Transcription factor SOX-7 OS=Mus ...514.7     33.9     27     59GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.
250Q8WW32    186   HMGB4_HUMAN High mobility group protein B4 OS...1260.058     38.9     27     46GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
251Q6TC41    221   SRY_MONSC Sex-determining region Y protein OS...514.4     33.5     33     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
252Q90ZH8    363   SX18A_XENLA Transcription factor Sox-18A OS=X...520.061     39.7     38     58GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
253Q8LDF9    241   HMGB7_ARATH High mobility group B protein 7 O...505     33.1     34     46GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IDA:TAIR.
254Q6CVH3    93   NHP6_KLULA Non-histone chromosomal protein 6 ...630.093     36.6     33     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
255Q9BT81    388   SOX7_HUMAN Transcription factor SOX-7 OS=Homo...586.5     33.1     28     59GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
GO:0001706; P:endoderm formation; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
256P26586    271   HMGL_TRYBR High mobility group protein homolo...630.86     35.8     30     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
257Q10666    438   POP1_CAEEL Protein pop-1 OS=Caenorhabditis el...710.074     39.7     32     56GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008013; F:beta-catenin binding; IPI:WormBase.::GO:0035035; F:histone acetyltransferase binding; IPI:WormBase.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:WormBase.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008356; P:asymmetric cell division; IMP:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007500; P:mesodermal cell fate determination; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0043282; P:pharyngeal muscle development; IMP:WormBase.::GO:0010085; P:polarity specification of proximal/distal axis; IGI:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0009786; P:regulation of asymmetric cell division; IGI:WormBase.::GO:0042659; P:regulation of cell fate specification; IGI:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.
258Q32PP9    238   SOX14_DANRE Transcription factor Sox-14 OS=Da...1311.9     34.7     24     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0021854; P:hypothalamus development; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
259Q9USU7    310   YHHB_SCHPO HMG box-containing protein C28F2.1...830.077     39.3     33     52GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; IGI:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:PomBase.
260Q9NP66    347   HM20A_HUMAN High mobility group protein 20A O...810.13     38.5     28     52GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
261Q9UVL1    92   NHP6_CANAL Non-histone chromosomal protein 6 ...710.75     33.9     27     46GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IDA:CGD.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
262P40628    242   HMGH_IIV6 High mobility group protein homolog...420.14     38.1     40     62GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
263A4QNG3    239   SOX14_XENTR Transcription factor Sox-14 OS=Xe...583.6     33.5     34     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
264P40651    72   MG42_TARMA SRY-related protein MG42 OS=Tarent...520.085     36.6     35     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
265O64702    151   HMG14_ARATH High mobility group B protein 14 ...780.17     37     26     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
266P91943    751   PANG1_DROME Protein pangolin, isoforms A/H/I ...598.3     33.1     24     58GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005667; C:transcription factor complex; IPI:FlyBase.
GO:0008013; F:beta-catenin binding; IBA:RefGenome.::GO:0019900; F:kinase binding; IPI:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.
GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0007507; P:heart development; TAS:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007500; P:mesodermal cell fate determination; TAS:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; NAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0072091; P:regulation of stem cell proliferation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IEA:UniProtKB-KW.::GO:0035277; P:spiracle morphogenesis, open tracheal system; IMP:FlyBase.
267B0ZTE2    239   SOX14_XENLA Transcription factor Sox-14 OS=Xe...585.6     33.1     34     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
268O15417    2968   TNC18_HUMAN Trinucleotide repeat-containing g...730.093     39.7     37     52
GO:0003677; F:DNA binding; IEA:InterPro.
269P40638    72   AES2_ALLMI SRY-related protein AES2 OS=Alliga...660.52     34.3     29     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
270Q65WY8    640   SSP1B_ORYSJ FACT complex subunit SSRP1-B OS=O...782.1     35     27     49
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
271P61259    240   SOX14_MACFA Transcription factor SOX-14 OS=Ma...586.1     33.1     34     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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