| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q4AEG9 | 197 | GPX4_CEBAP Phospholipid hydroperoxide glutath... | 148 | 4e-24 | 98.2 | 39 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:InterPro.::GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 62 | Q8SSH7 | 177 | GPX_ENCCU Probable phospholipid hydroperoxide... | 144 | 7e-24 | 97.1 | 39 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:InterPro.::GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 63 | Q4AEH0 | 197 | GPX4_MACFU Phospholipid hydroperoxide glutath... | 150 | 8e-24 | 97.4 | 38 | 55 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:InterPro.::GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 64 | Q95003 | 224 | GPX3_CAEEL Glutathione peroxidase OS=Caenorha... | 184 | 1e-23 | 97.8 | 35 | 51 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 65 | Q91XR8 | 253 | GPX42_RAT Phospholipid hydroperoxide glutathi... | 149 | 1e-23 | 98.2 | 38 | 55 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0043295; F:glutathione binding; IDA:RGD.::GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB.::GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IDA:RGD.::GO:0008430; F:selenium binding; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006325; P:chromatin organization; ISS:UniProtKB.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IDA:RGD.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0050727; P:regulation of inflammatory response; IMP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 66 | P04041 | 201 | GPX1_RAT Glutathione peroxidase 1 OS=Rattus n... | 186 | 3e-23 | 96.3 | 35 | 52 | GO:0005829; C:cytosol; TAS:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0043295; F:glutathione binding; IDA:RGD.::GO:0004602; F:glutathione peroxidase activity; IDA:RGD.::GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IMP:RGD.::GO:0008430; F:selenium binding; IMP:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IDA:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0051593; P:response to folic acid; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0006982; P:response to lipid hydroperoxide; IMP:RGD.::GO:0035094; P:response to nicotine; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD. | 67 | Q91XR9 | 253 | GPX42_MOUSE Phospholipid hydroperoxide glutat... | 149 | 9e-23 | 95.5 | 38 | 54 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IDA:MGI.::GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006325; P:chromatin organization; IDA:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEA:InterPro.::GO:0007283; P:spermatogenesis; IDA:MGI. | 68 | Q4AEH1 | 197 | GPX4_HYLLA Phospholipid hydroperoxide glutath... | 151 | 1e-22 | 94.4 | 38 | 53 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:InterPro.::GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 69 | P11352 | 201 | GPX1_MOUSE Glutathione peroxidase 1 OS=Mus mu... | 183 | 1e-22 | 94.4 | 36 | 52 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IDA:MGI. | | | | | | | | | | GO:0060055; P:angiogenesis involved in wound healing; IMP:MGI.::GO:0043534; P:blood vessel endothelial cell migration; IMP:MGI.::GO:0001885; P:endothelial cell development; IMP:MGI.::GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0060047; P:heart contraction; IMP:MGI.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:MGI.::GO:0008631; P:induction of apoptosis by oxidative stress; IMP:MGI.::GO:0051450; P:myoblast proliferation; IMP:MGI.::GO:0014902; P:myotube differentiation; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0018158; P:protein oxidation; IMP:MGI.::GO:0043523; P:regulation of neuron apoptotic process; IMP:MGI.::GO:0033194; P:response to hydroperoxide; IMP:MGI.::GO:0009636; P:response to toxin; IMP:MGI.::GO:0009410; P:response to xenobiotic stimulus; IMP:MGI.::GO:0007605; P:sensory perception of sound; IMP:MGI.::GO:0048741; P:skeletal muscle fiber development; IMP:MGI.::GO:0043403; P:skeletal muscle tissue regeneration; IMP:MGI.::GO:0006641; P:triglyceride metabolic process; IMP:MGI.::GO:0042311; P:vasodilation; IMP:MGI. | 70 | O08368 | 222 | GPWA_PSEWI Glutathione peroxidase OS=Pseudomo... | 125 | 5e-22 | 93.2 | 40 | 54 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 71 | P83564 | 201 | GPX1_CHLRE Glutathione peroxidase 1, mitochon... | 163 | 2e-21 | 90.9 | 40 | 51 | GO:0005739; C:mitochondrion; NAS:UniProtKB. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IDA:UniProtKB. | 72 | Q865R2 | 201 | GPX1_MACFU Glutathione peroxidase 1 OS=Macaca... | 188 | 4e-21 | 90.5 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 73 | P28714 | 221 | GPX5_MACFA Epididymal secretory glutathione p... | 159 | 5e-21 | 90.5 | 38 | 52 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 74 | Q4AEI3 | 201 | GPX1_PONPY Glutathione peroxidase 1 OS=Pongo ... | 189 | 6e-21 | 89.7 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 75 | P07203 | 203 | GPX1_HUMAN Glutathione peroxidase 1 OS=Homo s... | 189 | 1e-20 | 89 | 33 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:BHF-UCL. | | | | | | | | | | GO:0004866; F:endopeptidase inhibitor activity; IDA:BHF-UCL.::GO:0004602; F:glutathione peroxidase activity; IDA:BHF-UCL.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:BHF-UCL.::GO:0045454; P:cell redox homeostasis; IDA:BHF-UCL.::GO:0006749; P:glutathione metabolic process; IDA:BHF-UCL.::GO:0060047; P:heart contraction; IMP:BHF-UCL.::GO:0042744; P:hydrogen peroxide catabolic process; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.::GO:0006144; P:purine base metabolic process; TAS:Reactome.::GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.::GO:0040029; P:regulation of gene expression, epigenetic; IDA:BHF-UCL.::GO:0033599; P:regulation of mammary gland epithelial cell proliferation; IMP:BHF-UCL.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:BHF-UCL.::GO:0001836; P:release of cytochrome c from mitochondria; IMP:BHF-UCL.::GO:0010269; P:response to selenium ion; IMP:BHF-UCL.::GO:0009650; P:UV protection; IMP:BHF-UCL. | 76 | Q4AEI2 | 201 | GPX1_HYLLA Glutathione peroxidase 1 OS=Hyloba... | 189 | 2e-20 | 88.6 | 32 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 77 | P00435 | 205 | GPX1_BOVIN Glutathione peroxidase 1 OS=Bos ta... | 186 | 3e-20 | 87.8 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 78 | O75715 | 221 | GPX5_HUMAN Epididymal secretory glutathione p... | 159 | 4e-20 | 87.8 | 38 | 52 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006629; P:lipid metabolic process; NAS:ProtInc.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 79 | Q8MJ14 | 206 | GPX1_PIG Glutathione peroxidase 1 OS=Sus scro... | 190 | 2e-19 | 85.9 | 33 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 80 | Q0EFA0 | 201 | GPX1_PANTR Glutathione peroxidase 1 OS=Pan tr... | 189 | 2e-19 | 85.9 | 32 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 81 | O18994 | 219 | GPX5_PIG Epididymal secretory glutathione per... | 158 | 4e-19 | 85.1 | 37 | 51 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 82 | P30710 | 221 | GPX5_RAT Epididymal secretory glutathione per... | 158 | 4e-19 | 85.1 | 37 | 50 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 83 | P37141 | 226 | GPX3_BOVIN Glutathione peroxidase 3 OS=Bos ta... | 158 | 8e-19 | 84.3 | 36 | 50 | GO:0005615; C:extracellular space; ISS:UniProtKB. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB.::GO:0008430; F:selenium binding; ISS:UniProtKB. | | | | | | | | | | GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 84 | Q98234 | 220 | GPX_MCV1 Glutathione peroxidase OS=Molluscum ... | 187 | 8e-19 | 84.3 | 31 | 48 | | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 85 | P67878 | 223 | GPXC_BRUPA Cuticular glutathione peroxidase O... | 162 | 8e-19 | 84.3 | 36 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 86 | P67877 | 223 | GPXC_BRUMA Cuticular glutathione peroxidase O... | 162 | 8e-19 | 84.3 | 36 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 87 | P21765 | 221 | GPX5_MOUSE Epididymal secretory glutathione p... | 158 | 9e-19 | 84.3 | 37 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 88 | P23764 | 226 | GPX3_RAT Glutathione peroxidase 3 OS=Rattus n... | 162 | 1e-18 | 84 | 36 | 49 | GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0043295; F:glutathione binding; IDA:RGD.::GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB.::GO:0008430; F:selenium binding; ISS:UniProtKB. | | | | | | | | | | GO:0007565; P:female pregnancy; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IDA:RGD.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0002238; P:response to molecule of fungal origin; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD. | 89 | Q4AEH5 | 226 | GPX3_HYLLA Glutathione peroxidase 3 OS=Hyloba... | 162 | 1e-18 | 84 | 36 | 49 | GO:0005615; C:extracellular space; ISS:UniProtKB. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB.::GO:0008430; F:selenium binding; ISS:UniProtKB. | | | | | | | | | | GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro. | 90 | P11909 | 200 | GPX1_RABIT Glutathione peroxidase 1 OS=Orycto... | 186 | 1e-18 | 83.6 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. | 91 | P35666 | 223 | GPXC_WUCBA Cuticular glutathione peroxidase O... | 180 | 2e-18 | 83.6 | 34 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004602; F:glutathione peroxidase activity; IEA:EC. | | | | | | | | | | GO:0006979; P:response to oxidative stress; IEA:InterPro. |
