UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKL025C

Length:

679

Number of sequences:

5887

Description:

YKL025C PAN3 SGDID:S000001508, Chr XI from 392279-390240, Genome Release 64-1-1, reverse complement, Verified ORF, "Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P36102	679	PAN3_YEAST PAB-dependent poly(A)-specific rib...	679	0	1387	100	100	GO:0031251; C:PAN complex; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0006301; P:postreplication repair; IPI:SGD.
2	Q75BU9	612	PAN3_ASHGO PAB-dependent poly(A)-specific rib...	692	9e-180	532	44	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
3	Q6FKP2	717	PAN3_CANGA PAB-dependent poly(A)-specific rib...	748	1e-169	509	40	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
4	Q6CP23	656	PAN3_KLULA PAB-dependent poly(A)-specific rib...	704	1e-153	466	42	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
5	Q6BRV5	660	PAN3_DEBHA PAB-dependent poly(A)-specific rib...	695	1e-91	305	32	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
6	A3LQL9	630	PAN3_PICST PAB-dependent poly(A)-specific rib...	697	2e-90	301	34	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
7	A5DCP8	620	PAN3_PICGU PAB-dependent poly(A)-specific rib...	693	4e-84	283	32	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
8	Q5BFB1	661	PAN3_EMENI PAB-dependent poly(A)-specific rib...	711	6e-84	284	30	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
9	A1CP31	659	PAN3_ASPCL PAB-dependent poly(A)-specific rib...	690	1e-81	278	31	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
10	Q2U0M4	662	PAN3_ASPOR PAB-dependent poly(A)-specific rib...	701	4e-81	276	30	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
11	Q5AK10	698	PAN3_CANAL PAB-dependent poly(A)-specific rib...	732	4e-78	269	31	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
12	A1D1Y5	661	PAN3_NEOFI PAB-dependent poly(A)-specific rib...	686	2e-77	266	30	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
13	Q0D0A1	653	PAN3_ASPTN PAB-dependent poly(A)-specific rib...	689	1e-76	264	30	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
14	A2QAQ3	664	PAN3_ASPNC PAB-dependent poly(A)-specific rib...	686	3e-76	263	30	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
15	Q6MY57	662	PAN3_ASPFU PAB-dependent poly(A)-specific rib...	700	9e-76	262	30	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
16	Q1E2S2	658	PAN3_COCIM PAB-dependent poly(A)-specific rib...	693	1e-75	261	30	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
17	Q2KFH6	680	PAN3_MAGO7 PAB-dependent poly(A)-specific rib...	692	2e-72	253	28	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
18	Q2H401	648	PAN3_CHAGB PAB-dependent poly(A)-specific rib...	703	3e-70	246	29	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
19	Q0V0I4	669	PAN3_PHANO PAB-dependent poly(A)-specific rib...	718	1e-67	240	28	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
20	Q7SDP4	656	PAN3_NEUCR PAB-dependent poly(A)-specific rib...	694	3e-66	236	29	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
21	Q6CBZ0	670	PAN3_YARLI PAB-dependent poly(A)-specific rib...	459	2e-63	228	33	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
22	P34653	632	YOT7_CAEEL Uncharacterized protein ZK632.7 OS...	447	2e-58	213	31	51
									GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
23	A5E2Y4	794	PAN3_LODEL PAB-dependent poly(A)-specific rib...	36	0.00004	50.4	56	69	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
24	A1L1C7	787	PAN3_XENTR PAB-dependent poly(A)-specific rib...	480	4e-51	193	28	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
25	Q58A45	887	PAN3_HUMAN PAB-dependent poly(A)-specific rib...	481	3e-50	191	27	53	GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
26	Q640Q5	837	PAN3_MOUSE PAB-dependent poly(A)-specific rib...	481	2e-49	189	27	52
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
27	P0CD65	746	PAN3_DICDI PAB-dependent poly(A)-specific rib...	452	5e-49	187	28	53	GO:0031251; C:PAN complex; ISS:dictyBase.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004535; F:poly(A)-specific ribonuclease activity; ISS:dictyBase.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0031124; P:mRNA 3'-end processing; ISS:dictyBase.::GO:0006301; P:postreplication repair; ISS:dictyBase.
28	Q9UST1	589	PAN3_SCHPO PAB-dependent poly(A)-specific rib...	72	0.15	38.9	31	47	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031251; C:PAN complex; ISS:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0031124; P:mRNA 3'-end processing; ISS:PomBase.::GO:0006301; P:postreplication repair; ISS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
29	O13865	681	PAN3L_SCHPO PAB-dependent poly(A)-specific ri...	713	2e-31	134	26	43	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0031251; C:PAN complex; ISS:PomBase.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
									GO:0031124; P:mRNA 3'-end processing; ISS:PomBase.::GO:0006301; P:postreplication repair; ISS:PomBase.
30	P49840	483	GSK3A_HUMAN Glycogen synthase kinase-3 alpha ...	135	0.022	41.6	25	46	GO:0030877; C:beta-catenin destruction complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:BHF-UCL.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB.
									GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; ISS:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IMP:BHF-UCL.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0010905; P:negative regulation of UDP-glucose catabolic process; IC:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; ISS:BHF-UCL.::GO:0030819; P:positive regulation of cAMP biosynthetic process; ISS:BHF-UCL.::GO:2000467; P:positive regulation of glycogen (starch) synthase activity; ISS:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; ISS:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; NAS:BHF-UCL.::GO:0003073; P:regulation of systemic arterial blood pressure; ISS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
31	P51136	467	GSK3_DICDI Glycogen synthase kinase-3 OS=Dict...	75	0.035	40.8	29	56
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
									GO:0031154; P:culmination involved in sorocarp development; IMP:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0030155; P:regulation of cell adhesion; TAS:dictyBase.::GO:0061118; P:regulation of positive chemotaxis to cAMP; IMP:dictyBase.::GO:0042306; P:regulation of protein import into nucleus; IMP:dictyBase.::GO:0007165; P:signal transduction; IMP:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:UniProtKB.

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