Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL024C
Length:
204
Number of sequences:
5887
Description:
YKL024C URA6 SGDID:S000001507, Chr XI from 393140-392526, Genome Release 64-1-1, reverse complement, Verified ORF, "Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P15700    204   UMPK_YEAST Uridylate kinase OS=Saccharomyces ...2047e-149     419     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004017; F:adenylate kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009041; F:uridylate kinase activity; IDA:SGD.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:SGD.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
2O59771    191   UMPK_SCHPO Probable uridylate kinase OS=Schiz...1898e-67     209     53     74GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009041; F:uridylate kinase activity; ISS:PomBase.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; ISS:PomBase.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
3Q7ZX23    193   KCY_XENLA UMP-CMP kinase OS=Xenopus laevis (A...1864e-64     203     53     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IEA:InterPro.
GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
4Q7ZWE9    196   KCY_DANRE UMP-CMP kinase OS=Danio rerio (Zebr...1885e-64     203     51     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IEA:InterPro.
GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
5Q28H12    196   KCY_XENTR UMP-CMP kinase OS=Xenopus tropicali...1866e-64     202     53     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IEA:InterPro.
GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
6Q5ZKE7    196   KCY_CHICK UMP-CMP kinase OS=Gallus gallus (Ch...1841e-63     202     54     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IEA:InterPro.
GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
7P20425    195   KCY_DICDI UMP-CMP kinase OS=Dictyostelium dis...1887e-63     200     54     74GO:0005622; C:intracellular; IC:dictyBase.
GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0004127; F:cytidylate kinase activity; IDA:dictyBase.::GO:0000287; F:magnesium ion binding; IDA:dictyBase.::GO:0033862; F:UMP kinase activity; IDA:dictyBase.
GO:0046705; P:CDP biosynthetic process; IDA:dictyBase.::GO:0043173; P:nucleotide salvage; IDA:dictyBase.::GO:0043100; P:pyrimidine base salvage; IDA:dictyBase.::GO:0006225; P:UDP biosynthetic process; IDA:dictyBase.
8O04905    202   UMPK_ARATH UMP/CMP kinase OS=Arabidopsis thal...1821e-62     199     54     74GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IDA:TAIR.::GO:0009041; F:uridylate kinase activity; IDA:TAIR.
GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0009173; P:pyrimidine ribonucleoside monophosphate metabolic process; TAS:TAIR.
9Q4KM73    196   KCY_RAT UMP-CMP kinase OS=Rattus norvegicus (...1843e-60     193     51     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0033862; F:UMP kinase activity; IDA:RGD.
GO:0046705; P:CDP biosynthetic process; IDA:RGD.::GO:0006240; P:dCDP biosynthetic process; IDA:RGD.::GO:0006227; P:dUDP biosynthetic process; IDA:RGD.::GO:0022602; P:ovulation cycle process; IEP:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0006225; P:UDP biosynthetic process; IDA:RGD.
10Q9DBP5    196   KCY_MOUSE UMP-CMP kinase OS=Mus musculus (Mou...1845e-60     192     51     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IEA:InterPro.
GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
11Q29561    196   KCY_PIG UMP-CMP kinase OS=Sus scrofa (Pig). G...1841e-59     191     51     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IEA:InterPro.
GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
12P30085    196   KCY_HUMAN UMP-CMP kinase OS=Homo sapiens (Hum...1841e-59     191     51     72GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IEA:InterPro.::GO:0004849; F:uridine kinase activity; TAS:ProtInc.
GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
13Q2KIW9    196   KCY_BOVIN UMP-CMP kinase OS=Bos taurus (Bovin...1841e-59     191     51     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004127; F:cytidylate kinase activity; IEA:EC.::GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IEA:InterPro.
GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
14Q20140    210   KAD1_CAEEL Probable adenylate kinase isoenzym...1782e-55     181     45     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046034; P:ATP metabolic process; IEA:InterPro.
15P00571    194   KAD1_PIG Adenylate kinase isoenzyme 1 OS=Sus ...1791e-52     174     47     69
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046034; P:ATP metabolic process; IEA:InterPro.
16P00570    194   KAD1_BOVIN Adenylate kinase isoenzyme 1 OS=Bo...1821e-52     173     46     69
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046034; P:ATP metabolic process; IEA:InterPro.
17P39069    194   KAD1_RAT Adenylate kinase isoenzyme 1 OS=Ratt...1824e-51     169     45     69GO:0043005; C:neuron projection; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0030017; C:sarcomere; IDA:RGD.
GO:0004017; F:adenylate kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046083; P:adenine metabolic process; NAS:RGD.::GO:0006172; P:ADP biosynthetic process; IDA:RGD.::GO:0046033; P:AMP metabolic process; IDA:RGD.::GO:0046034; P:ATP metabolic process; IEA:InterPro.::GO:0021549; P:cerebellum development; IEP:RGD.::GO:0046103; P:inosine biosynthetic process; IDA:RGD.::GO:0007517; P:muscle organ development; IEP:RGD.::GO:0030182; P:neuron differentiation; IEP:RGD.::GO:0021772; P:olfactory bulb development; IEP:RGD.::GO:0010828; P:positive regulation of glucose transport; IMP:RGD.::GO:0014042; P:positive regulation of neuron maturation; IEP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.
18P00568    194   KAD1_HUMAN Adenylate kinase isoenzyme 1 OS=Ho...1826e-51     169     46     68GO:0005829; C:cytosol; TAS:Reactome.
GO:0004017; F:adenylate kinase activity; TAS:ProtInc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046034; P:ATP metabolic process; IEA:InterPro.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
19P00569    194   KAD1_RABIT Adenylate kinase isoenzyme 1 OS=Or...1827e-51     169     46     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046034; P:ATP metabolic process; IEA:InterPro.
20O24464    231   KAD_PRUAR Adenylate kinase OS=Prunus armeniac...1832e-49     166     46     68
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
21P12115    194   KAD1_CYPCA Adenylate kinase isoenzyme 1 OS=Cy...1832e-49     165     42     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046034; P:ATP metabolic process; IEA:InterPro.
22Q9R0Y5    194   KAD1_MOUSE Adenylate kinase isoenzyme 1 OS=Mu...1822e-48     162     43     69GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0004017; F:adenylate kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046034; P:ATP metabolic process; IEA:InterPro.::GO:0007050; P:cell cycle arrest; IDA:MGI.
23P05081    194   KAD1_CHICK Adenylate kinase isoenzyme 1 OS=Ga...1795e-48     162     43     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046034; P:ATP metabolic process; IEA:InterPro.
24P25824    197   KAD_SCHMA Adenylate kinase OS=Schistosoma man...1903e-47     160     43     68
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
25Q7MW54    194   KAD_PORGI Adenylate kinase OS=Porphyromonas g...1787e-37     132     37     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
26B2RIY8    194   KAD_PORG3 Adenylate kinase OS=Porphyromonas g...1788e-37     132     37     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
27A6LD69    190   KAD_PARD8 Adenylate kinase OS=11152). GN=adk ...1889e-37     132     35     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
28Q89ZJ0    189   KAD_BACTN Adenylate kinase OS=10582 / E50 / V...1864e-35     128     35     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
29Q9Y6K8    562   KAD5_HUMAN Adenylate kinase isoenzyme 5 OS=Ho...1882e-34     132     34     59GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0004017; F:adenylate kinase activity; TAS:ProtInc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0019206; F:nucleoside kinase activity; EXP:Reactome.
GO:0006172; P:ADP biosynthetic process; TAS:ProtInc.::GO:0046034; P:ATP metabolic process; IEA:InterPro.::GO:0006173; P:dADP biosynthetic process; TAS:ProtInc.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0009220; P:pyrimidine ribonucleotide biosynthetic process; TAS:ProtInc.::GO:0007165; P:signal transduction; IEA:InterPro.
30A6L0Z9    189   KAD_BACV8 Adenylate kinase OS=Bacteroides vul...1864e-34     125     34     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
31A4IFD0    562   KAD5_BOVIN Adenylate kinase isoenzyme 5 OS=Bo...1887e-34     130     34     59
GO:0004017; F:adenylate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.
GO:0046034; P:ATP metabolic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
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