Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL021C
Length:
468
Number of sequences:
5887
Description:
YKL021C MAK11 SGDID:S000001504, Chr XI from 398750-397344, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
931P62872    340   GBB1_CANFA Guanine nucleotide-binding protein...1615.4     33.1     22     39
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
932P62871    340   GBB1_BOVIN Guanine nucleotide-binding protein...1615.4     33.1     22     39GO:0005834; C:heterotrimeric G-protein complex; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:BHF-UCL.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007191; P:activation of adenylate cyclase activity by dopamine receptor signaling pathway; IDA:BHF-UCL.::GO:0071870; P:cellular response to catecholamine stimulus; IDA:BHF-UCL.::GO:0071380; P:cellular response to prostaglandin E stimulus; IDA:BHF-UCL.
933Q86H45    901   ELP2_DICDI Probable elongator complex protein...1415.5     33.5     23     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008023; C:transcription elongation factor complex; ISS:dictyBase.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:dictyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
934O42249    317   GBLP_ORENI Guanine nucleotide-binding protein...645.6     32.7     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
935Q5RHI5    647   DTL_DANRE Denticleless protein homolog OS=Dan...1495.7     33.1     22     43GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:ZFIN.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
936A4IIX9    494   WDR37_XENTR WD repeat-containing protein 37 O...1535.8     33.1     20     43
937Q6CU59    444   YTM1_KLULA Ribosome biogenesis protein YTM1 O...1695.8     33.1     22     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
938C4R6H3    500   LIS1_PICPG Nuclear distribution protein PAC1 ...1225.9     33.1     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
939P0CS44    757   MDV1_CRYNJ Mitochondrial division protein 1 O...805.9     33.1     28     51GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
940P0CS45    757   MDV1_CRYNB Mitochondrial division protein 1 O...805.9     33.1     28     51GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
941Q9I9H8    1261   APAF_DANRE Apoptotic protease-activating fact...655.9     33.1     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006952; P:defense response; IEA:InterPro.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
942B3MEY6    411   LIS1_DROAN Lissencephaly-1 homolog OS=Drosoph...376     33.1     32     59GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
943P79959    340   GBB1_XENLA Guanine nucleotide-binding protein...1616     32.7     22     39
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
944Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...1296.1     33.1     26     43
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
945Q9ERF3    305   WDR61_MOUSE WD repeat-containing protein 61 O...1326.1     32.7     25     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
946Q6NS57    1503   MABP1_MOUSE Mitogen-activated protein kinase-...1426.2     33.1     24     43
GO:0005515; F:protein binding; IPI:MGI.
GO:0007256; P:activation of JNKK activity; IDA:MGI.
947Q96J01    351   THOC3_HUMAN THO complex subunit 3 OS=Homo sap...1936.2     32.7     22     36GO:0000346; C:transcription export complex; IDA:UniProtKB.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0046784; P:intronless viral mRNA export from host nucleus; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
948Q29RH4    351   THOC3_BOVIN THO complex subunit 3 OS=Bos taur...1936.4     32.7     22     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
949Q4R2Z6    622   WDR48_MACFA WD repeat-containing protein 48 O...746.4     33.1     27     51GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
950B4HRQ6    335   CIAO1_DROSE Probable cytosolic iron-sulfur pr...1466.4     32.7     27     42
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
951B6GZA1    673   SCONB_PENCW Probable E3 ubiquitin ligase comp...1186.5     33.1     22     43
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
952Q922V4    513   PLRG1_MOUSE Pleiotropic regulator 1 OS=Mus mu...1366.5     33.1     24     42GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
953Q5NVD0    521   PRP4_PONAB U4/U6 small nuclear ribonucleoprot...1746.5     33.1     17     39GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
954Q5REG7    410   LIS1_PONAB Platelet-activating factor acetylh...756.5     32.7     20     53GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
955Q8TEQ6    1508   GEMI5_HUMAN Gem-associated protein 5 OS=Homo ...536.5     33.1     36     51GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0017069; F:snRNA binding; IDA:UniProtKB.
GO:0034660; P:ncRNA metabolic process; TAS:Reactome.::GO:0006461; P:protein complex assembly; TAS:UniProtKB.::GO:0000387; P:spliceosomal snRNP assembly; TAS:UniProtKB.
956O43172    522   PRP4_HUMAN U4/U6 small nuclear ribonucleoprot...1746.6     33.1     17     39GO:0015030; C:Cajal body; IDA:BHF-UCL.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; NAS:UniProtKB.::GO:0071001; C:U4/U6 snRNP; IDA:BHF-UCL.
GO:0005515; F:protein binding; IPI:BHF-UCL.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:BHF-UCL.
957Q8SQS4    556   TAF5_ENCCU Transcription initiation factor TF...2106.7     33.1     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
958Q9GL51    410   LIS1_PIG Platelet-activating factor acetylhyd...756.7     32.7     20     53GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
959Q8VE80    351   THOC3_MOUSE THO complex subunit 3 OS=Mus musc...1936.7     32.7     22     36
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
960P63004    410   LIS1_RAT Platelet-activating factor acetylhyd...756.8     32.7     20     53GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0005871; C:kinesin complex; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0042598; C:vesicular fraction; IDA:RGD.
GO:0045505; F:dynein intermediate chain binding; IDA:RGD.::GO:0047179; F:platelet-activating factor acetyltransferase activity; TAS:RGD.
GO:0021895; P:cerebral cortex neuron differentiation; IMP:RGD.::GO:0051660; P:establishment of centrosome localization; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010977; P:negative regulation of neuron projection development; IMP:RGD.::GO:0001764; P:neuron migration; IMP:RGD.::GO:0007097; P:nuclear migration; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD.::GO:0017145; P:stem cell division; IMP:RGD.
961P63005    410   LIS1_MOUSE Platelet-activating factor acetylh...756.8     32.7     20     53GO:0005813; C:centrosome; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0008017; F:microtubule binding; IDA:MGI.::GO:0051219; F:phosphoprotein binding; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.
GO:0001675; P:acrosome assembly; IMP:MGI.::GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IGI:MGI.::GO:0007611; P:learning or memory; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007405; P:neuroblast proliferation; IMP:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0051081; P:nuclear envelope disassembly; IMP:MGI.::GO:0032319; P:regulation of Rho GTPase activity; IMP:MGI.::GO:0008090; P:retrograde axon cargo transport; IDA:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.
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