Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL021C
Length:
468
Number of sequences:
5887
Description:
YKL021C MAK11 SGDID:S000001504, Chr XI from 398750-397344, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91A6ZYM0    330   CIAO1_YEAS7 Probable cytosolic iron-sulfur pr...2670.00002     50.1     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
92P90794    571   DCA11_CAEEL DDB1- and CUL4-associated factor ...3000.00002     50.4     21     38GO:0005634; C:nucleus; IDA:WormBase.
GO:0008134; F:transcription factor binding; IPI:WormBase.
GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:WormBase.::GO:0080135; P:regulation of cellular response to stress; IMP:WormBase.
93B6QC56    459   LIS11_PENMQ Nuclear distribution protein nudF...1670.00003     49.7     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
94Q8VBV4    629   FBXW7_MOUSE F-box/WD repeat-containing protei...1650.00003     50.1     24     43GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
95Q920J3    472   CORO6_RAT Coronin-6 OS=Rattus norvegicus (Rat...710.00003     50.1     38     58GO:0015629; C:actin cytoskeleton; IBA:RefGenome.
GO:0051015; F:actin filament binding; IBA:RefGenome.
GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
96Q920M5    471   CORO6_MOUSE Coronin-6 OS=Mus musculus (Mouse)...710.00003     49.7     38     58GO:0015629; C:actin cytoskeleton; IBA:RefGenome.
GO:0051015; F:actin filament binding; IBA:RefGenome.
GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
97Q7RY68    660   PFS2_NEUCR Polyadenylation factor subunit 2 O...2300.00003     50.1     26     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
98B4QB64    668   WDR48_DROSI WD repeat-containing protein 48 h...1980.00003     50.1     23     41
99Q2HBX6    454   LIS11_CHAGB Nuclear distribution protein PAC1...1530.00004     49.3     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
100Q969H0    707   FBXW7_HUMAN F-box/WD repeat-containing protei...1660.00004     49.7     24     42GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL.
101B4HND9    680   WDR48_DROSE WD repeat-containing protein 48 h...1980.00004     50.1     23     41
102Q4R4J2    461   COR1A_MACFA Coronin-1A OS=Macaca fascicularis...800.00004     49.7     40     54GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
103Q759U7    461   LIS1_ASHGO Nuclear distribution protein PAC1 ...1650.00004     49.7     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
104A0JPH4    1311   SCAP_XENLA Sterol regulatory element-binding ...2020.00004     50.1     27     37GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
105A7EF03    335   EIF3I_SCLS1 Eukaryotic translation initiation...790.00004     48.9     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
106Q9BRP4    392   PAAF1_HUMAN Proteasomal ATPase-associated fac...1780.00004     49.3     27     40GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
107A8NEG8    434   LIS1_COPC7 Nuclear distribution protein PAC1 ...2720.00005     48.9     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
108Q61666    1015   HIRA_MOUSE Protein HIRA OS=Mus musculus (Mous...1360.00005     49.7     26     46GO:0000790; C:nuclear chromatin; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
109Q9SJT9    1218   COPA2_ARATH Coatomer subunit alpha-2 OS=Arabi...1860.00005     49.7     25     44GO:0030126; C:COPI vesicle coat; IEA:InterPro.::GO:0005829; C:cytosol; IDA:TAIR.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
110Q8BU03    919   PWP2_MOUSE Periodic tryptophan protein 2 homo...1150.00005     49.7     28     47GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
111B7PS00    411   LIS1_IXOSC Lissencephaly-1 homolog OS=Ixodes ...1690.00006     48.9     25     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
112A8XEN7    554   DCA11_CAEBR DDB1- and CUL4-associated factor ...1490.00006     49.3     23     45
GO:0008340; P:determination of adult lifespan; ISS:UniProtKB.
113Q24572    430   CAF1_DROME Probable histone-binding protein C...2360.00006     48.9     26     43GO:0033186; C:CAF-1 complex; IDA:FlyBase.::GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0031523; C:Myb complex; IDA:FlyBase.::GO:0016581; C:NuRD complex; IDA:FlyBase.::GO:0016589; C:NURF complex; IPI:FlyBase.::GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0070822; C:Sin3-type complex; IDA:FlyBase.::GO:0005667; C:transcription factor complex; IPI:FlyBase.
GO:0035035; F:histone acetyltransferase binding; IPI:FlyBase.::GO:0042393; F:histone binding; IDA:FlyBase.::GO:0042826; F:histone deacetylase binding; IDA:FlyBase.::GO:0042803; F:protein homodimerization activity; IPI:FlyBase.
GO:0006342; P:chromatin silencing; IPI:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0006281; P:DNA repair; TAS:FlyBase.::GO:0007307; P:eggshell chorion gene amplification; IC:FlyBase.::GO:0016573; P:histone acetylation; IDA:FlyBase.::GO:0070734; P:histone H3-K27 methylation; IC:GOC.::GO:0051567; P:histone H3-K9 methylation; IC:GOC.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.::GO:0006334; P:nucleosome assembly; IDA:FlyBase.::GO:0042766; P:nucleosome mobilization; IDA:FlyBase.::GO:0016584; P:nucleosome positioning; IDA:FlyBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:FlyBase.::GO:0007379; P:segment specification; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IDA:FlyBase.
114Q91ZN1    461   COR1A_RAT Coronin-1A OS=Rattus norvegicus (Ra...800.00006     48.9     40     54GO:0030864; C:cortical actin cytoskeleton; IBA:RefGenome.::GO:0030027; C:lamellipodium; IBA:RefGenome.::GO:0001891; C:phagocytic cup; IBA:RefGenome.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; IBA:RefGenome.
GO:0030595; P:leukocyte chemotaxis; IBA:RefGenome.::GO:0051126; P:negative regulation of actin nucleation; IBA:RefGenome.::GO:0001845; P:phagolysosome assembly; IBA:RefGenome.::GO:0050918; P:positive chemotaxis; IBA:RefGenome.::GO:0008360; P:regulation of cell shape; IBA:RefGenome.::GO:0030217; P:T cell differentiation; NAS:RGD.::GO:0032796; P:uropod organization; IBA:RefGenome.
115Q4ICM0    464   LIS1_GIBZE Nuclear distribution protein PAC1 ...2690.00007     48.9     21     38GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
116Q17963    376   TG125_CAEEL WD repeat-containing protein tag-...3200.00007     48.5     20     41GO:0005634; C:nucleus; IDA:WormBase.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051568; P:histone H3-K4 methylation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
117Q676U5    607   A16L1_HUMAN Autophagy-related protein 16-1 OS...1370.00007     48.9     26     45GO:0005776; C:autophagic vacuole; ISS:UniProtKB.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000045; P:autophagic vacuole assembly; NAS:UniProtKB.::GO:0051260; P:protein homooligomerization; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
118O89053    461   COR1A_MOUSE Coronin-1A OS=Mus musculus (Mouse...800.00007     48.5     40     54GO:0030864; C:cortical actin cytoskeleton; IBA:RefGenome.::GO:0001772; C:immunological synapse; IDA:MGI.::GO:0030027; C:lamellipodium; IBA:RefGenome.::GO:0001891; C:phagocytic cup; IBA:RefGenome.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; IDA:MGI.
GO:0007015; P:actin filament organization; IMP:MGI.::GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.::GO:0030595; P:leukocyte chemotaxis; IMP:MGI.::GO:0051126; P:negative regulation of actin nucleation; IBA:RefGenome.::GO:0001845; P:phagolysosome assembly; IBA:RefGenome.::GO:0050918; P:positive chemotaxis; IBA:RefGenome.::GO:0030335; P:positive regulation of cell migration; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0030833; P:regulation of actin filament polymerization; IMP:MGI.::GO:0008360; P:regulation of cell shape; IMP:MGI.::GO:0034097; P:response to cytokine stimulus; IMP:MGI.::GO:0043029; P:T cell homeostasis; IMP:MGI.::GO:0032796; P:uropod organization; IMP:MGI.
119A6RUL1    335   EIF3I_BOTFB Eukaryotic translation initiation...730.00008     48.1     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
120A1DP19    441   LIS1_NEOFI Nuclear distribution protein nudF ...3170.00009     48.5     21     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
121C5DF48    457   LIS1_LACTC Nuclear distribution protein PAC1 ...3380.00009     48.5     22     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
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