Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL021C
Length:
468
Number of sequences:
5887
Description:
YKL021C MAK11 SGDID:S000001504, Chr XI from 398750-397344, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
811P63247    317   GBLP_CHICK Guanine nucleotide-binding protein...641.6     34.7     33     48GO:0043025; C:neuronal cell body; ISS:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB.
812P63243    317   GBLP_BOVIN Guanine nucleotide-binding protein...641.6     34.7     33     48GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001891; C:phagocytic cup; ISS:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; ISS:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
813O42248    317   GBLP_DANRE Guanine nucleotide-binding protein...641.6     34.7     33     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0051302; P:regulation of cell division; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:UniProtKB.
814B0X2V9    670   WDR48_CULQU WD repeat-containing protein 48 h...711.6     35     31     54
815Q0CCP0    784   ERB1_ASPTN Ribosome biogenesis protein erb1 O...1461.6     35     29     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
816Q4WEI5    436   HAT2_ASPFU Histone acetyltransferase type B s...861.6     34.7     31     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
817B4KKN1    419   WDR12_DROMO Ribosome biogenesis protein WDR12...1341.6     34.7     22     45GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
818Q4RJN5    410   LIS1_TETNG Lissencephaly-1 homolog OS=nigrovi...751.7     34.7     21     53GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
819Q8HXL3    1541   WDR62_PIG WD repeat-containing protein 62 OS=...1631.7     35     25     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0021987; P:cerebral cortex development; ISS:UniProtKB.
820Q55AR8    355   SNR40_DICDI U5 small nuclear ribonucleoprotei...401.7     34.7     40     58GO:0005681; C:spliceosomal complex; ISS:dictyBase.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:dictyBase.
821Q8TEB1    546   DCA11_HUMAN DDB1- and CUL4-associated factor ...1441.7     35     22     39GO:0080008; C:CUL4 RING ubiquitin ligase complex; IDA:UniProtKB.
GO:0016567; P:protein ubiquitination; IC:UniProtKB.
822Q16K15    326   EIF3I_AEDAE Eukaryotic translation initiation...1801.7     34.7     19     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
823Q4WTI3    795   ERB1_ASPFU Ribosome biogenesis protein erb1 O...1261.7     35     30     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
824B0XQ42    796   ERB1_ASPFC Ribosome biogenesis protein erb1 O...1261.7     35     30     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0051726; P:regulation of cell cycle; IEA:InterPro.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
825Q9DAW6    521   PRP4_MOUSE U4/U6 small nuclear ribonucleoprot...1741.8     34.7     18     39GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
826P16649    713   TUP1_YEAST General transcriptional corepresso...1371.8     35     23     45GO:0017053; C:transcriptional repressor complex; IDA:SGD.
GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD.
827P87177    922   YB1C_SCHPO Uncharacterized WD repeat-containi...1271.8     35     24     40GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0032040; C:small-subunit processome; ISS:PomBase.
GO:0030515; F:snoRNA binding; ISS:PomBase.
GO:0030490; P:maturation of SSU-rRNA; ISS:PomBase.
828Q5M9G8    549   DCA11_RAT DDB1- and CUL4-associated factor 11...1441.8     34.7     23     39GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.
829Q6NZH4    410   LIS1_XENTR Lissencephaly-1 homolog OS=Xenopus...751.9     34.7     23     53GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
830Q6H8D6    910   COB23_ORYSJ Putative coatomer subunit beta'-3...2281.9     34.7     21     37GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
831Q09990    665   LIN23_CAEEL F-box/WD repeat-containing protei...1052     34.7     23     42GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048812; P:neuron projection morphogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
832Q90ZL4    410   LIS1_XENLA Lissencephaly-1 homolog OS=Xenopus...752     34.7     23     53GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
833Q8BHD1    476   POC1B_MOUSE POC1 centriolar protein homolog B...1122     34.7     23     41GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.
834P87060    775   POP1_SCHPO WD repeat-containing protein pop1 ...1502     34.7     21     40GO:0005634; C:nucleus; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0006995; P:cellular response to nitrogen starvation; IGI:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0008054; P:cyclin catabolic process; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
835C5DY07    444   LIS1_ZYGRC Nuclear distribution protein PAC1 ...1372     34.7     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
836A3LNI7    524   LIS1_PICST Nuclear distribution protein PAC1 ...1132     34.7     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
837A1D3I2    462   CIAO1_NEOFI Probable cytosolic iron-sulfur pr...1112     34.7     24     47
838Q39836    325   GBLP_SOYBN Guanine nucleotide-binding protein...642.1     34.3     31     50
839Q39336    327   GBLP_BRANA Guanine nucleotide-binding protein...642.1     34.3     31     50
840Q2UA71    436   HAT2_ASPOR Histone acetyltransferase type B s...952.1     34.3     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
841Q6RI45    1802   BRWD3_HUMAN Bromodomain and WD repeat-contain...1212.2     34.7     26     42
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
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