Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL021C
Length:
468
Number of sequences:
5887
Description:
YKL021C MAK11 SGDID:S000001504, Chr XI from 398750-397344, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P20484    468   MAK11_YEAST Protein MAK11 OS=Saccharomyces ce...4680     971     100     100GO:0005624; C:membrane fraction; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.
2Q5ZKU8    369   PK1IP_CHICK p21-activated protein kinase-inte...3673e-37     144     29     47GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
3Q9DCE5    382   PK1IP_MOUSE p21-activated protein kinase-inte...3524e-34     136     28     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
4Q6TNS2    368   PK1IP_DANRE p21-activated protein kinase-inte...3134e-33     132     28     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
5Q5EA99    392   PK1IP_BOVIN p21-activated protein kinase-inte...3466e-33     132     28     47GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
6Q9NWT1    392   PK1IP_HUMAN p21-activated protein kinase-inte...4065e-32     130     25     45GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
7Q68FJ6    363   PK1IP_XENLA p21-activated protein kinase-inte...3495e-29     120     28     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
8O74453    341   SKB15_SCHPO Shk1 kinase-binding protein 15 OS...1820.0000000000006     73.6     27     47GO:0030685; C:nucleolar preribosome; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004860; F:protein kinase inhibitor activity; IMP:PomBase.
GO:0071775; P:regulation of cell cycle cytokinesis; IGI:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase.::GO:0042254; P:ribosome biogenesis; IMP:PomBase.
9C4JZS6    446   LIS11_UNCRE Nuclear distribution protein PAC1...3640.00000000001     69.7     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
10O43017    380   SWD3_SCHPO Set1 complex component swd3 OS=Sch...1570.00000000009     67     29     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0051568; P:histone H3-K4 methylation; IMP:PomBase.
11Q6FJZ9    427   PRP46_CANGA Pre-mRNA-splicing factor PRP46 OS...2440.0000000001     67     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
12Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...2910.0000000003     65.9     24     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
13Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...2910.0000000004     65.5     24     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
14Q4V7Y7    655   KTNB1_XENLA Katanin p80 WD40-containing subun...2260.000000002     63.9     21     45GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
15P90648    732   MHCKB_DICDI Myosin heavy chain kinase B OS=Di...1750.000000003     62.8     26     45GO:0005826; C:actomyosin contractile ring; IDA:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0045159; F:myosin II binding; IPI:dictyBase.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0031037; P:myosin II filament disassembly; IMP:dictyBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.
16A1CF18    435   LIS12_ASPCL Nuclear distribution protein nudF...3230.000000005     61.6     22     36GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
17Q6CKE8    434   PRP46_KLULA Pre-mRNA-splicing factor PRP46 OS...1690.000000006     61.6     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
18Q5RD06    451   POC1B_PONAB POC1 centriolar protein homolog B...3300.00000001     60.5     21     40GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.
19Q6GM65    799   PLAP_XENLA Phospholipase A-2-activating prote...3370.00000002     60.5     25     42
GO:0005488; F:binding; IEA:InterPro.
20Q15542    800   TAF5_HUMAN Transcription initiation factor TF...2550.00000003     60.1     22     38GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005669; C:transcription factor TFIID complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0016573; P:histone acetylation; IDA:GOC.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
21Q8C092    801   TAF5_MOUSE Transcription initiation factor TF...2550.00000003     59.7     22     38GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22Q7RY30    453   LIS11_NEUCR Nuclear distribution protein pac1...3490.00000004     58.9     21     35GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
23B6QC06    452   LIS12_PENMQ Nuclear distribution protein nudF...1500.00000007     58.2     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
24Q6C709    441   PRP46_YARLI Pre-mRNA-splicing factor PRP46 OS...1900.0000001     57     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
25A8X8C6    368   TG125_CAEBR WD repeat-containing protein tag-...3050.0000002     56.2     24     42
26Q7ZVA0    513   SMU1_DANRE WD40 repeat-containing protein SMU...1380.0000003     56.2     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
27Q229Z6    634   POC1_TETTS POC1 centriolar protein homolog OS...1410.0000004     56.2     26     46GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0051297; P:centrosome organization; IMP:UniProtKB.
28Q23256    501   YH92_CAEEL Uncharacterized WD repeat-containi...1260.0000005     55.5     30     51
29Q7ZVF0    416   POC1A_DANRE POC1 centriolar protein homolog A...1340.0000005     55.5     26     48
30Q93847    395   YZLL_CAEEL Uncharacterized WD repeat-containi...2950.0000005     55.5     23     42
31Q5A7Q3    389   PRP46_CANAL Pre-mRNA-splicing factor PRP46 OS...2910.0000005     55.5     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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