Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL020C
Length:
1082
Number of sequences:
5887
Description:
YKL020C SPT23 SGDID:S000001503, Chr XI from 402080-398832, Genome Release 64-1-1, reverse complement, Verified ORF, "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Mga2p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P35210    1082   SPT23_YEAST Protein SPT23 OS=Saccharomyces ce...10820     2209     100     100GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003677; F:DNA binding; IPI:SGD.
GO:0070417; P:cellular response to cold; IGI:SGD.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:SGD.::GO:0036083; P:positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter; IGI:SGD.
2P40578    1113   MGA2_YEAST Protein MGA2 OS=Saccharomyces cere...10580     613     39     55GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0070417; P:cellular response to cold; IMP:SGD.::GO:0048255; P:mRNA stabilization; IMP:SGD.::GO:0061399; P:positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion; IMP:SGD.::GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0036083; P:positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter; IGI:SGD.
3O13987    1151   YEG5_SCHPO Ankyrin and IPT/TIG repeat-contain...3370.032     42     22     39GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0045723; P:positive regulation of fatty acid biosynthetic process; ISS:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:PomBase.
4Q12955    4377   ANK3_HUMAN Ankyrin-3 OS=Homo sapiens (Human)....602     36.2     32     57GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045184; P:establishment of protein localization; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
5Q2QLG9    1655   CTTB2_OTOGA Cortactin-binding protein 2 OS=Ot...540.77     37.7     33     59
6Q2IBF8    1653   CTTB2_EULMM Cortactin-binding protein 2 OS=Eu...790.0000004     58.2     38     54
7Q7Z8U2    737   AKR1_ASPOR Palmitoyltransferase akr1 OS=Asper...760.0000005     57.4     36     57GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
8Q9ULJ7    1429   ANR50_HUMAN Ankyrin repeat domain-containing ...701.6     36.6     33     50
9Q505D1    1053   ANR28_MOUSE Serine/threonine-protein phosphat...596.9     34.3     36     51GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
10Q07DW4    1642   CTTB2_MUNRE Cortactin-binding protein 2 OS=Mu...790.000002     55.8     37     56
11P16157    1881   ANK1_HUMAN Ankyrin-1 OS=Homo sapiens (Human)....661.3     37     30     52GO:0016323; C:basolateral plasma membrane; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.::GO:0016529; C:sarcoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0014731; C:spectrin-associated cytoskeleton; IDA:BHF-UCL.
GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0030507; F:spectrin binding; NAS:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0006887; P:exocytosis; NAS:UniProtKB.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; TAS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
12Q9QZH2    768   BARD1_RAT BRCA1-associated RING domain protei...590.000003     55.5     46     64GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEP:RGD.
13P77736    201   YAHD_ECOLI Putative ankyrin repeat protein Ya...760.000003     52.8     33     58
14Q5UPV1    728   YL271_MIMIV Putative ankyrin repeat protein L...1010.000003     55.1     39     51
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
15Q02357    1862   ANK1_MOUSE Ankyrin-1 OS=Mus musculus (Mouse)....554.4     35     35     55GO:0030863; C:cortical cytoskeleton; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0016529; C:sarcoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0014731; C:spectrin-associated cytoskeleton; IMP:MGI.
GO:0048821; P:erythrocyte development; IMP:MGI.::GO:0015672; P:monovalent inorganic cation transport; IMP:MGI.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
16Q95N27    568   PP16B_BOVIN Protein phosphatase 1 regulatory ...910.0003     48.5     26     56GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0051489; P:regulation of filopodium assembly; IMP:UniProtKB.
17Q2QL82    1647   CTTB2_MICMU Cortactin-binding protein 2 OS=Mi...790.000004     54.7     37     54
18Q09YK4    1660   CTTB2_ATEGE Cortactin-binding protein 2 OS=mo...790.000006     54.7     35     53
19Q09YJ3    1642   CTTB2_MUNMU Cortactin-binding protein 2 OS=Mu...790.000006     54.3     37     54
20Q09YI1    1641   CTTB2_SHEEP Cortactin-binding protein 2 OS=Ov...790.000006     54.3     37     54
21Q07E28    1658   CTTB2_NEONE Cortactin-binding protein 2 OS=Ne...545.4     35     31     59
22Q99728    777   BARD1_HUMAN BRCA1-associated RING domain prot...1290.000008     53.9     32     48GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; TAS:UniProtKB.
23A0M8T5    1658   CTTB2_FELCA Cortactin-binding protein 2 OS=Fe...543.3     35.4     31     59
24Q54KA7    986   SECG_DICDI Ankyrin repeat, PH and SEC7 domain...686.3     34.7     34     46GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
25Q3UES3    1166   TNKS2_MOUSE Tankyrase-2 OS=Mus musculus (Mous...600.87     37.4     37     53GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.
GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
26Q4X251    738   AKR1_ASPFU Palmitoyltransferase akr1 OS=A1100...760.00001     53.1     33     58GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27Q9H2K2    1166   TNKS2_HUMAN Tankyrase-2 OS=Homo sapiens (Huma...591.5     36.6     37     53GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IC:BHF-UCL.::GO:0005635; C:nuclear envelope; IDA:BHF-UCL.::GO:0000242; C:pericentriolar material; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IC:BHF-UCL.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
28O70445    765   BARD1_MOUSE BRCA1-associated RING domain prot...590.00001     53.1     42     63GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB.
29Q96T49    567   PP16B_HUMAN Protein phosphatase 1 regulatory ...910.0003     48.5     26     56GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0019903; F:protein phosphatase binding; NAS:UniProtKB.
GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.
30Q96NW4    1050   ANR27_HUMAN Ankyrin repeat domain-containing ...572.8     35.8     35     56GO:0005769; C:early endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:LIFEdb.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
GO:0045022; P:early endosome to late endosome transport; IDA:MGI.
31O15084    1053   ANR28_HUMAN Serine/threonine-protein phosphat...593.9     35.4     36     51GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
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