Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL019W
Length:
316
Number of sequences:
5887
Description:
YKL019W RAM2 SGDID:S000001502, Chr XI from 402568-403518, Genome Release 64-1-1, Verified ORF, "Alpha subunit of both the farnesyltransferase and type I geranylgeranyltransferase that catalyze prenylation of proteins containing a CAAX consensus motif; essential protein required for membrane localization of Ras proteins and a-factor"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P29703    316   FNTA_YEAST Protein farnesyltransferase/gerany...3160     652     100     100GO:0005953; C:CAAX-protein geranylgeranyltransferase complex; IDA:SGD.::GO:0005965; C:protein farnesyltransferase complex; IDA:SGD.
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004660; F:protein farnesyltransferase activity; IDA:SGD.
GO:0007323; P:peptide pheromone maturation; IDA:SGD.::GO:0018343; P:protein farnesylation; IDA:SGD.::GO:0018344; P:protein geranylgeranylation; IDA:SGD.
2Q9Y765    306   FNTA_CANAX Protein farnesyltransferase/gerany...3216e-62     205     39     59
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0004660; F:protein farnesyltransferase activity; IEA:EC.
GO:0018342; P:protein prenylation; IEA:InterPro.
3O60052    294   FNTA_SCHPO Protein farnesyltransferase/gerany...2228e-51     176     43     60GO:0005953; C:CAAX-protein geranylgeranyltransferase complex; NAS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004660; F:protein farnesyltransferase activity; IEA:EC.
GO:0034411; P:cell wall (1->3)-beta-D-glucan biosynthetic process; IPI:PomBase.::GO:0018344; P:protein geranylgeranylation; IC:PomBase.::GO:0006612; P:protein targeting to membrane; IC:PomBase.
4P93227    346   FNTA_SOLLC Protein farnesyltransferase/gerany...2542e-41     152     36     54
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0004660; F:protein farnesyltransferase activity; IEA:EC.
GO:0018342; P:protein prenylation; IEA:InterPro.
5Q54RT9    322   FNTA_DICDI Protein farnesyltransferase/gerany...3227e-38     142     31     51GO:0005965; C:protein farnesyltransferase complex; ISS:dictyBase.
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0004660; F:protein farnesyltransferase activity; ISS:dictyBase.
GO:0018343; P:protein farnesylation; ISS:dictyBase.
6Q61239    377   FNTA_MOUSE Protein farnesyltransferase/gerany...2235e-36     138     31     57
GO:0030548; F:acetylcholine receptor regulator activity; IMP:MGI.::GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0004660; F:protein farnesyltransferase activity; IDA:UniProtKB.::GO:0004663; F:Rab geranylgeranyltransferase activity; IDA:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
GO:0045213; P:neurotransmitter receptor metabolic process; IMP:MGI.::GO:0018342; P:protein prenylation; IEA:InterPro.
7Q04631    377   FNTA_RAT Protein farnesyltransferase/geranylg...2231e-35     137     31     57GO:0005953; C:CAAX-protein geranylgeranyltransferase complex; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0004660; F:protein farnesyltransferase activity; IDA:RGD.
GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0051771; P:negative regulation of nitric-oxide synthase biosynthetic process; IMP:RGD.::GO:0045787; P:positive regulation of cell cycle; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IMP:RGD.::GO:0018342; P:protein prenylation; IEA:InterPro.::GO:0034097; P:response to cytokine stimulus; IMP:RGD.::GO:0010035; P:response to inorganic substance; IMP:RGD.::GO:0014070; P:response to organic cyclic compound; IMP:RGD.
8P29702    375   FNTA_BOVIN Protein farnesyltransferase/gerany...2233e-35     136     31     58
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0004660; F:protein farnesyltransferase activity; IEA:EC.
GO:0018342; P:protein prenylation; IEA:InterPro.
9P49354    379   FNTA_HUMAN Protein farnesyltransferase/gerany...2234e-35     136     30     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0005875; C:microtubule associated complex; IDA:BHF-UCL.
GO:0043014; F:alpha-tubulin binding; IDA:BHF-UCL.::GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0008017; F:microtubule binding; IDA:BHF-UCL.::GO:0004660; F:protein farnesyltransferase activity; TAS:ProtInc.
GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0090045; P:positive regulation of deacetylase activity; IDA:BHF-UCL.::GO:0090044; P:positive regulation of tubulin deacetylation; IDA:BHF-UCL.::GO:0018343; P:protein farnesylation; IDA:BHF-UCL.::GO:0018344; P:protein geranylgeranylation; TAS:ProtInc.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
10O24304    333   FNTA_PEA Protein farnesyltransferase/geranylg...3191e-33     131     31     49
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0004660; F:protein farnesyltransferase activity; IEA:EC.
GO:0018342; P:protein prenylation; IEA:InterPro.
11Q9LX33    326   FNTA_ARATH Protein farnesyltransferase/gerany...3214e-26     109     29     49GO:0005953; C:CAAX-protein geranylgeranyltransferase complex; IPI:TAIR.::GO:0005965; C:protein farnesyltransferase complex; IPI:TAIR.
GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:EC.::GO:0004311; F:farnesyltranstransferase activity; TAS:TAIR.::GO:0004660; F:protein farnesyltransferase activity; IEA:EC.::GO:0046982; F:protein heterodimerization activity; IPI:TAIR.
GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0018343; P:protein farnesylation; TAS:TAIR.::GO:0018344; P:protein geranylgeranylation; IDA:TAIR.::GO:0008360; P:regulation of cell shape; IMP:TAIR.::GO:0048509; P:regulation of meristem development; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.
12Q08602    567   PGTA_RAT Geranylgeranyl transferase type-2 su...1928e-18     87.4     28     47
GO:0004663; F:Rab geranylgeranyltransferase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0018344; P:protein geranylgeranylation; IDA:RGD.
13Q9JHK4    567   PGTA_MOUSE Geranylgeranyl transferase type-2 ...1330.071     38.5     26     39
GO:0004663; F:Rab geranylgeranyltransferase activity; IMP:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0018344; P:protein geranylgeranylation; IMP:MGI.
14Q92696    567   PGTA_HUMAN Geranylgeranyl transferase type-2 ...1160.053     38.9     27     41
GO:0004663; F:Rab geranylgeranyltransferase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007601; P:visual perception; TAS:ProtInc.
15Q5NVK5    567   PGTA_PONAB Geranylgeranyl transferase type-2 ...1160.058     38.9     27     41
GO:0004663; F:Rab geranylgeranyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0018342; P:protein prenylation; IEA:InterPro.
16Q5EA80    567   PGTA_BOVIN Geranylgeranyl transferase type-2 ...1160.16     37.4     27     41
GO:0004663; F:Rab geranylgeranyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
17A5A779    567   PGTA_PIG Geranylgeranyl transferase type-2 su...1150.034     39.3     27     43
GO:0004663; F:Rab geranylgeranyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
18Q00618    327   PGTA_YEAST Geranylgeranyl transferase type-2 ...1960.00000000000001     76.6     28     52GO:0005968; C:Rab-protein geranylgeranyltransferase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004663; F:Rab geranylgeranyltransferase activity; IDA:SGD.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0018344; P:protein geranylgeranylation; IDA:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.
19O94412    344   PGTA_SCHPO Geranylgeranyl transferase type-2 ...3290.000000000007     68.9     25     43GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005968; C:Rab-protein geranylgeranyltransferase complex; ISS:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0004663; F:Rab geranylgeranyltransferase activity; ISS:PomBase.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0018344; P:protein geranylgeranylation; ISS:PomBase.::GO:0006612; P:protein targeting to membrane; IC:PomBase.
20Q55DQ4    311   PGTA_DICDI Geranylgeranyl transferase type-2 ...1401.5     33.9     23     41GO:0005968; C:Rab-protein geranylgeranyltransferase complex; ISS:dictyBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004663; F:Rab geranylgeranyltransferase activity; ISS:dictyBase.
GO:0018344; P:protein geranylgeranylation; ISS:dictyBase.
21O93829    371   PGTA_CANAX Geranylgeranyl transferase type-2 ...3410.0000000007     63.2     23     41
GO:0004663; F:Rab geranylgeranyltransferase activity; IEA:EC.
GO:0018342; P:protein prenylation; IEA:InterPro.
22P32610    256   VATD_YEAST V-type proton ATPase subunit D OS=...760.023     39.3     32     50GO:0000329; C:fungal-type vacuole membrane; TAS:SGD.::GO:0000221; C:vacuolar proton-transporting V-type ATPase, V1 domain; TAS:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; TAS:SGD.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0007035; P:vacuolar acidification; TAS:SGD.
23O59941    264   VATD_NEUCR V-type proton ATPase subunit D OS=...811     34.3     33     51GO:0033178; C:proton-transporting two-sector ATPase complex, catalytic domain; IEA:InterPro.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IDA:UniProtKB.
GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IDA:UniProtKB.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0007035; P:vacuolar acidification; IDA:UniProtKB.
24Q5UPX2    204   YL288_MIMIV Putative B-type lectin protein L2...425.4     32     33     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
records
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