Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL018W
Length:
329
Number of sequences:
5887
Description:
YKL018W SWD2 SGDID:S000001501, Chr XI from 404102-405091, Genome Release 64-1-1, Verified ORF, "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q32LN7    305   WDR61_BOVIN WD repeat-containing protein 61 O...1510.0001     46.6     30     44GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
152Q9GZS3    305   WDR61_HUMAN WD repeat-containing protein 61 O...1510.0002     46.6     30     44GO:0016593; C:Cdc73/Paf1 complex; IDA:UniProtKB.::GO:0055087; C:Ski complex; IDA:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; IMP:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
153Q4V7A0    305   WDR61_RAT WD repeat-containing protein 61 OS=...1510.0002     46.6     30     44GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
154P0CS49    473   PRP46_CRYNB Pre-mRNA-splicing factor PRP46 OS...1180.089     38.1     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
155P0CS48    473   PRP46_CRYNJ Pre-mRNA-splicing factor PRP46 OS...1180.09     38.1     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
156P79147    340   GBB3_CANFA Guanine nucleotide-binding protein...1840.0002     46.6     24     42GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
157Q2KID6    513   PLRG1_BOVIN Pleiotropic regulator 1 OS=Bos ta...2160.07     38.5     21     41GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
158P79959    340   GBB1_XENLA Guanine nucleotide-binding protein...1710.0002     46.2     26     43
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
159Q5I0B9    622   ATG16_XENTR Autophagy-related protein 16 OS=X...2610.0002     46.6     21     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
160P0CS42    433   LIS1_CRYNJ Nuclear distribution protein PAC1 ...2620.0002     46.2     21     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
161P0CS43    433   LIS1_CRYNB Nuclear distribution protein PAC1 ...2620.0002     46.2     21     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
162Q9NRL3    753   STRN4_HUMAN Striatin-4 OS=Homo sapiens (Human...3180.0002     46.6     19     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.
163Q8W1K8    370   MUT11_CHLRE Protein Mut11 OS=Chlamydomonas re...1410.31     36.2     21     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
164Q9BQ87    522   TBL1Y_HUMAN F-box-like/WD repeat-containing p...1480.89     35     24     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
165Q8R537    318   PEX7_CRIGR Peroxisomal targeting signal 2 rec...1200.0002     45.8     23     49GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0005053; F:peroxisome matrix targeting signal-2 binding; ISS:UniProtKB.
GO:0008611; P:ether lipid biosynthetic process; ISS:UniProtKB.::GO:0016558; P:protein import into peroxisome matrix; ISS:UniProtKB.
166Q9WUC8    514   PLRG1_RAT Pleiotropic regulator 1 OS=Rattus n...1021.7     34.3     24     47GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
167O43660    514   PLRG1_HUMAN Pleiotropic regulator 1 OS=Homo s...2160.059     38.9     21     41GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
168Q9BQA1    342   MEP50_HUMAN Methylosome protein 50 OS=Homo sa...1030.0003     45.8     32     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IGI:MGI.
GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IGI:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0034660; P:ncRNA metabolic process; TAS:Reactome.::GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.
169O76734    579   TUP1_DICDI General transcriptional corepresso...1613.5     33.1     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
170Q922V4    513   PLRG1_MOUSE Pleiotropic regulator 1 OS=Mus mu...1033.8     33.1     21     48GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
171P16520    340   GBB3_HUMAN Guanine nucleotide-binding protein...1840.0003     45.8     24     43GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0008217; P:regulation of blood pressure; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome.
172Q8I0F4    419   LIS1_DICDI Lissencephaly-1 homolog OS=Dictyos...1050.26     36.6     27     46GO:0031592; C:centrosomal corona; IDA:dictyBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0045504; F:dynein heavy chain binding; IPI:dictyBase.::GO:0017048; F:Rho GTPase binding; IPI:dictyBase.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051642; P:centrosome localization; IMP:dictyBase.::GO:0051645; P:Golgi localization; IMP:dictyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
173Q6TMK6    340   GBB1_CRIGR Guanine nucleotide-binding protein...1710.0003     45.8     26     42
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
174P53622    1201   COPA_YEAST Coatomer subunit alpha OS=Saccharo...1190.0003     46.2     24     50GO:0030126; C:COPI vesicle coat; IMP:SGD.
GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.
175Q39190    479   PRL2_ARATH Protein pleiotropic regulator PRL2...1350.0003     45.8     21     47GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.
176P54311    340   GBB1_RAT Guanine nucleotide-binding protein G...1710.0003     45.4     26     42GO:0005834; C:heterotrimeric G-protein complex; TAS:RGD.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0010659; P:cardiac muscle cell apoptotic process; IDA:MGI.::GO:0071456; P:cellular response to hypoxia; IDA:MGI.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:RGD.
177P62874    340   GBB1_MOUSE Guanine nucleotide-binding protein...1710.0003     45.4     26     42GO:0005834; C:heterotrimeric G-protein complex; IPI:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; IDA:MGI.::GO:0008283; P:cell proliferation; IDA:MGI.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0050909; P:sensory perception of taste; IDA:MGI.
178P62873    340   GBB1_HUMAN Guanine nucleotide-binding protein...1710.0003     45.4     26     42GO:0005834; C:heterotrimeric G-protein complex; IDA:MGI.::GO:0005624; C:membrane fraction; ISS:BHF-UCL.
GO:0003924; F:GTPase activity; IDA:MGI.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007191; P:activation of adenylate cyclase activity by dopamine receptor signaling pathway; ISS:BHF-UCL.::GO:0071870; P:cellular response to catecholamine stimulus; ISS:BHF-UCL.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0071380; P:cellular response to prostaglandin E stimulus; ISS:BHF-UCL.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome.
179P62872    340   GBB1_CANFA Guanine nucleotide-binding protein...1710.0003     45.4     26     42
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
180P62871    340   GBB1_BOVIN Guanine nucleotide-binding protein...1710.0003     45.4     26     42GO:0005834; C:heterotrimeric G-protein complex; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:BHF-UCL.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007191; P:activation of adenylate cyclase activity by dopamine receptor signaling pathway; IDA:BHF-UCL.::GO:0071870; P:cellular response to catecholamine stimulus; IDA:BHF-UCL.::GO:0071380; P:cellular response to prostaglandin E stimulus; IDA:BHF-UCL.
181Q2TBP4    407   POC1A_BOVIN POC1 centriolar protein homolog A...1780.074     38.5     21     39GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.
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