Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL017C
Length:
683
Number of sequences:
5887
Description:
YKL017C HCS1 SGDID:S000001500, Chr XI from 407241-405190, Genome Release 64-1-1, reverse complement, Verified ORF, "Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P47386    1113   Y140_MYCGE Uncharacterized ATP-dependent heli...740.024     41.6     31     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
62P75033    1113   Y153_MYCPN Uncharacterized ATP-dependent heli...1360.095     39.7     25     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
63P0C6W1    7126   R1AB_BC133 Replicase polyprotein 1ab OS=Bat c...2690.015     42.7     23     38GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
64P39369    338   YJHR_ECOLI Putative uncharacterized protein y...950.017     41.6     32     57
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
65P0C6W4    7182   R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat c...2690.15     39.3     23     38GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
66O74111    338   RFC3_BLAAD Replication factor C subunit 3 OS=...680.2     38.1     31     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
67P48752    446   PIVA2_ADE40 Maturation protein OS=Human adeno...990.23     38.1     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0019083; P:viral transcription; IEA:InterPro.
68P0C6W2    7067   R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat c...910.4     37.7     32     47GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
69P0C6V9    7079   R1AB_BC279 Replicase polyprotein 1ab OS=Bat c...910.4     37.7     30     46GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
70P0C6X7    7073   R1AB_CVHSA Replicase polyprotein 1ab OS=coron...910.41     37.7     30     46GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
71P0C6W6    7071   R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat c...910.43     37.7     30     46GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
72P38126    564   PCH2_YEAST Pachytene checkpoint protein 2 OS=...290.51     37.4     52     69GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0040020; P:regulation of meiosis; TAS:SGD.
73Q03W49    1230   ADDA_LEUMM ATP-dependent helicase/nuclease su...400.52     37.4     45     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006302; P:double-strand break repair; IEA:InterPro.
74Q9HHR1    428   CDC65_HALSA Cell division control protein 6 h...1450.7     36.6     22     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
75O94508    1284   CWF11_SCHPO Pre-mRNA-splicing factor cwf11 OS...2934.5     34.3     23     41GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
76Q55G81    776   ERCC2_DICDI TFIIH basal transcription factor ...391.1     36.2     38     56GO:0000443; C:SSL2-core TFIIH complex portion of holo TFIIH complex; ISS:dictyBase.::GO:0000442; C:SSL2-core TFIIH complex portion of NEF3 complex; ISS:dictyBase.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; ISS:dictyBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:dictyBase.
GO:0006289; P:nucleotide-excision repair; ISS:dictyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:dictyBase.
77A5N628    1235   ADDA_CLOK5 ATP-dependent helicase/nuclease su...731.1     36.6     34     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006302; P:double-strand break repair; IEA:InterPro.
78Q9Y7C4    578   ROK1_CANAL ATP-dependent RNA helicase CHR1 OS...1391.1     36.2     30     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
79P75356    353   Y432_MYCPN Putative ABC transporter ATP-bindi...781.2     35.8     36     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0006810; P:transport; IEA:UniProtKB-KW.
80Q54E21    338   RFC2_DICDI Probable replication factor C subu...961.3     35.4     27     51GO:0005663; C:DNA replication factor C complex; ISS:dictyBase.::GO:0031391; C:Elg1 RFC-like complex; ISS:dictyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0031389; C:Rad17 RFC-like complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006272; P:leading strand elongation; ISS:dictyBase.::GO:0006298; P:mismatch repair; ISS:dictyBase.
81B9DZK4    1238   ADDA_CLOK1 ATP-dependent helicase/nuclease su...731.6     35.8     34     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006302; P:double-strand break repair; IEA:InterPro.
82Q6YQE1    670   UVRB_ONYPE UvrABC system protein B OS=Onion y...891.9     35.4     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
83Q58914    1175   Y1519_METJA Uncharacterized protein MJ1519 OS...702.1     35.4     34     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
84Q2NJ77    667   UVRB_AYWBP UvrABC system protein B OS=Aster y...892.1     35.4     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
85Q3JCW5    149   FABZ_NITOC (3R)-hydroxymyristoyl-[acyl-carrie...752.1     33.9     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016836; F:hydro-lyase activity; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
86P73090    328   PHOL_SYNY3 PhoH-like protein OS=Synechocystis...502.4     34.7     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
87Q47F81    144   FABZ_DECAR (3R)-hydroxymyristoyl-[acyl-carrie...712.5     33.5     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016836; F:hydro-lyase activity; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
88Q3UA06    432   PCH2_MOUSE Pachytene checkpoint protein 2 hom...332.8     34.7     45     61GO:0001673; C:male germ cell nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006302; P:double-strand break repair; IMP:UniProtKB.::GO:0007144; P:female meiosis I; IMP:MGI.::GO:0007141; P:male meiosis I; IMP:MGI.::GO:0001556; P:oocyte maturation; IMP:MGI.::GO:0000239; P:pachytene; IMP:MGI.::GO:0007131; P:reciprocal meiotic recombination; IMP:UniProtKB.::GO:0007286; P:spermatid development; IMP:MGI.::GO:0007130; P:synaptonemal complex assembly; IMP:UniProtKB.
89Q5XHZ9    432   PCH2_RAT Pachytene checkpoint protein 2 homol...332.8     34.7     45     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
90D3K5L7    431   PCH2_PIG Pachytene checkpoint protein 2 homol...332.9     34.7     45     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
91E2R222    432   PCH2_CANFA Pachytene checkpoint protein 2 hom...332.9     34.7     45     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
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