Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL012W
Length:
583
Number of sequences:
5887
Description:
YKL012W PRP40 SGDID:S000001495, Chr XI from 418310-420061, Genome Release 64-1-1, Verified ORF, "U1 snRNP protein involved in splicing, interacts with the branchpoint-binding protein during the formation of the second commitment complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q9VVI3    1007   NEDD4_DROME E3 ubiquitin-protein ligase Nedd-...323.9     34.3     41     63GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0007528; P:neuromuscular junction development; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0002092; P:positive regulation of receptor internalization; IMP:FlyBase.::GO:0051965; P:positive regulation of synapse assembly; IMP:FlyBase.::GO:0031623; P:receptor internalization; IMP:UniProtKB.
62Q7NBS1    159   GREA_MYCGA Transcription elongation factor Gr...1201.8     33.9     31     47
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
63Q8CFI0    1004   NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4...532.9     34.7     34     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
64Q5SXA9    1104   KIBRA_MOUSE Protein KIBRA OS=Mus musculus (Mo...382.1     35     47     61GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.
GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
65Q6ZWJ1    553   STXB4_HUMAN Syntaxin-binding protein 4 OS=Hom...292.3     34.7     48     59GO:0005737; C:cytoplasm; IDA:HPA.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005509; F:calcium ion binding; IEA:InterPro.
66Q5R9W5    414   WWOX_PONAB WW domain-containing oxidoreductas...922.3     34.7     25     46GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
67P46191    488   SYK_MYCHP Lysine--tRNA ligase OS=PG21). GN=ly...762.5     34.7     26     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004824; F:lysine-tRNA ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006430; P:lysyl-tRNA aminoacylation; IEA:InterPro.
68Q6P964    420   P4R2A_DANRE Serine/threonine-protein phosphat...1852.5     34.7     25     42
69Q59XV0    844   SET2_CANAL Histone-lysine N-methyltransferase...272.8     34.7     52     74GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
70Q5RBF2    959   NED4L_PONAB E3 ubiquitin-protein ligase NEDD4...282.9     34.7     50     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
71Q96PU5    975   NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4...533     34.7     34     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.::GO:0007588; P:excretion; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.::GO:0010038; P:response to metal ion; IDA:UniProtKB.::GO:0006814; P:sodium ion transport; NAS:UniProtKB.::GO:0030104; P:water homeostasis; NAS:UniProtKB.
72B4HEJ6    1295   KIBRA_DROSE Protein kibra OS=Drosophila seche...733.3     34.7     29     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
73B4NAD3    1288   KIBRA_DROWI Protein kibra OS=Drosophila willi...733.5     34.3     30     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74Q9WV89    557   STXB4_MOUSE Syntaxin-binding protein 4 OS=Mus...293.6     34.3     48     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0015758; P:glucose transport; IDA:MGI.::GO:0008286; P:insulin receptor signaling pathway; IDA:MGI.::GO:0006605; P:protein targeting; IDA:MGI.
75Q9LK71    560   DGP11_ARATH Putative protease Do-like 11, mit...873.7     34.3     30     49GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
76B3P3M8    1283   KIBRA_DROER Protein kibra OS=Drosophila erect...733.7     34.3     29     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
77Q9VFG8    1288   KIBRA_DROME Protein kibra OS=Drosophila melan...733.9     34.3     29     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0001745; P:compound eye morphogenesis; IGI:FlyBase.::GO:0035330; P:regulation of hippo signaling cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78B4PSQ2    1288   KIBRA_DROYA Protein kibra OS=Drosophila yakub...733.9     34.3     29     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
79Q91WL8    414   WWOX_MOUSE WW domain-containing oxidoreductas...924.3     33.9     25     46GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
80O88382    1277   MAGI2_RAT Membrane-associated guanylate kinas...464.7     33.9     35     54GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0036057; C:slit diaphragm; IDA:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB.
GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB.
GO:0003094; P:glomerular filtration; IC:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; IDA:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0043113; P:receptor clustering; IDA:RGD.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.
81Q96QZ7    1491   MAGI1_HUMAN Membrane-associated guanylate kin...644.8     33.9     34     55GO:0042995; C:cell projection; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0051393; F:alpha-actinin binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0006461; P:protein complex assembly; NAS:ProtInc.
82Q9NZC7    414   WWOX_HUMAN WW domain-containing oxidoreductas...924.8     33.5     25     46GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
83Q6RHR9    1471   MAGI1_MOUSE Membrane-associated guanylate kin...644.9     33.9     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
84Q4A970    1412   RPOC_MYCHJ DNA-directed RNA polymerase subuni...1235.7     33.9     23     46
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
85Q4A7B0    1412   RPOC_MYCH7 DNA-directed RNA polymerase subuni...1235.9     33.9     23     46
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
86Q9WVQ1    1275   MAGI2_MOUSE Membrane-associated guanylate kin...465.9     33.5     35     54GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB.
GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IPI:MGI.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0070699; F:type II activin receptor binding; IPI:UniProtKB.
GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
87Q5ZZS2    1412   RPOC_MYCH2 DNA-directed RNA polymerase subuni...1236     33.5     23     46
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
88Q86UL8    1455   MAGI2_HUMAN Membrane-associated guanylate kin...636.1     33.5     32     49GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IDA:UniProtKB.
GO:0031697; F:beta-1 adrenergic receptor binding; IPI:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; IDA:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB.
GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0003402; P:planar cell polarity pathway involved in axis elongation; NAS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.
89Q9UPV0    1460   CE164_HUMAN Centrosomal protein of 164 kDa OS...467.3     33.5     35     52GO:0005814; C:centriole; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
90B4M5X4    1276   KIBRA_DROVI Protein kibra OS=Drosophila viril...737.4     33.5     29     49GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
91B4K6I9    1264   KIBRA_DROMO Protein kibra OS=Drosophila mojav...739.2     33.1     29     49GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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