Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL010C
Length:
1483
Number of sequences:
5887
Description:
YKL010C UFD4 SGDID:S000001493, Chr XI from 425875-421424, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P33202    1483   UFD4_YEAST Ubiquitin fusion degradation prote...14830     3044     100     100GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
2Q10435    1647   YDE1_SCHPO Probable ubiquitin fusion degradat...13968e-136     464     29     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
3Q6WWW4    1888   UPL3_ARATH E3 ubiquitin-protein ligase UPL3 O...4230.00000000001     73.9     22     42GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0042023; P:DNA endoreduplication; IMP:TAIR.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0010091; P:trichome branching; IMP:TAIR.
4Q9LYZ7    1502   UPL4_ARATH E3 ubiquitin-protein ligase UPL4 O...4750.000000000008     74.3     20     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
5Q14669    1992   TRIPC_HUMAN Probable E3 ubiquitin-protein lig...5423e-18     95.1     23     43GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
6Q9ULT8    2610   HECD1_HUMAN E3 ubiquitin-protein ligase HECTD...2064e-27     124     35     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
7Q69ZR2    2618   HECD1_MOUSE E3 ubiquitin-protein ligase HECTD...2094e-26     121     35     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0001843; P:neural tube closure; IMP:UniProtKB.
8Q8GY23    3681   UPL1_ARATH E3 ubiquitin-protein ligase UPL1 O...3732e-29     132     29     46GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
9Q8H0T4    3658   UPL2_ARATH E3 ubiquitin-protein ligase UPL2 O...3738e-28     127     29     46GO:0005829; C:cytosol; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
10F8W2M1    904   HACE1_DANRE E3 ubiquitin-protein ligase HACE1...4049e-27     122     26     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
11Q15386    1083   UBE3C_HUMAN Ubiquitin-protein ligase E3C OS=H...2994e-26     120     29     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
12Q80U95    1083   UBE3C_MOUSE Ubiquitin-protein ligase E3C OS=M...2996e-25     117     29     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
13O13834    3227   PTR1_SCHPO E3 ubiquitin-protein ligase ptr1 O...3017e-25     117     29     46GO:0005634; C:nucleus; IDA:PomBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
14E1C656    942   HACE1_CHICK E3 ubiquitin-protein ligase HACE1...4079e-25     115     25     44GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
15D3ZBM7    909   HACE1_RAT E3 ubiquitin-protein ligase HACE1 O...4071e-24     115     25     44GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q9P4Z1    4026   TOM1_NEUCR E3 ubiquitin-protein ligase TOM1-l...4001e-24     116     26     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
17Q3U0D9    909   HACE1_MOUSE E3 ubiquitin-protein ligase HACE1...4071e-24     115     25     44GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q8RWB8    1029   UPL6_ARATH E3 ubiquitin-protein ligase UPL6 O...4561e-24     115     25     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
19Q6DCL5    944   HACE1_XENLA E3 ubiquitin-protein ligase HACE1...4072e-24     115     25     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
20Q8IYU2    909   HACE1_HUMAN E3 ubiquitin-protein ligase HACE1...4072e-24     115     25     44GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; IMP:UniProtKB.::GO:0007030; P:Golgi organization; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016601; P:Rac protein signal transduction; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21F1N6G5    909   HACE1_BOVIN E3 ubiquitin-protein ligase HACE1...4075e-24     114     25     44GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22Q28BK1    912   HACE1_XENTR E3 ubiquitin-protein ligase HACE1...4075e-24     113     24     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
23Q9SCQ2    1142   UPL7_ARATH E3 ubiquitin-protein ligase UPL7 O...3086e-24     113     31     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
24O00308    870   WWP2_HUMAN NEDD4-like E3 ubiquitin-protein li...3089e-23     109     29     48GO:0005737; C:cytoplasm; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; TAS:ProtInc.
GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0051224; P:negative regulation of protein transport; IMP:UniProtKB.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0032410; P:negative regulation of transporter activity; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0046718; P:viral entry into host cell; TAS:UniProtKB.
25Q8C863    864   ITCH_MOUSE E3 ubiquitin-protein ligase Itchy ...4083e-22     108     26     45GO:0005938; C:cell cortex; IDA:MGI.::GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050687; P:negative regulation of defense response to virus; IMP:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IMP:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0002669; P:positive regulation of T cell anergy; IMP:MGI.::GO:0035519; P:protein K29-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:MGI.::GO:0090085; P:regulation of protein deubiquitination; IMP:BHF-UCL.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
26Q756G2    3258   TOM1_ASHGO Probable E3 ubiquitin-protein liga...4193e-22     108     27     44GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
27P51593    322   HUWE1_RAT E3 ubiquitin-protein ligase HUWE1 O...3115e-22     103     31     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016574; P:histone ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
28B8N7E5    812   RSP5_ASPFN Probable E3 ubiquitin-protein liga...3145e-22     107     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
29Q2UBP1    816   RSP5_ASPOR Probable E3 ubiquitin-protein liga...3146e-22     106     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
30Q9DBH0    870   WWP2_MOUSE NEDD4-like E3 ubiquitin-protein li...3088e-22     106     29     47GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IMP:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
31Q05086    875   UBE3A_HUMAN Ubiquitin-protein ligase E3A OS=H...2918e-22     106     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007420; P:brain development; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
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