Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR139C
Length:
359
Number of sequences:
5887
Description:
YJR139C HOM6 SGDID:S000003900, Chr X from 690524-689445, Genome Release 64-1-1, reverse complement, Verified ORF, "Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P31116    359   DHOM_YEAST Homoserine dehydrogenase OS=Saccha...3590     717     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004412; F:homoserine dehydrogenase activity; IDA:SGD.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
2O94671    376   DHOM_SCHPO Probable homoserine dehydrogenase ...3635e-113     340     53     72
GO:0004412; F:homoserine dehydrogenase activity; ISS:PomBase.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009090; P:homoserine biosynthetic process; ISS:PomBase.::GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; ISS:PomBase.::GO:0009088; P:threonine biosynthetic process; ISS:PomBase.
3Q5B998    368   DHOM_EMENI Homoserine dehydrogenase OS=194 / ...3543e-108     328     49     70
GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
4P49079    920   AKH1_MAIZE Bifunctional aspartokinase/homoser...3743e-82     274     43     61GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
5Q9SA18    911   AKH1_ARATH Bifunctional aspartokinase/homoser...2712e-77     261     48     71GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IDA:TAIR.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
6P49080    917   AKH2_MAIZE Bifunctional aspartokinase/homoser...2744e-77     260     47     68
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
7P37142    921   AKH_DAUCA Bifunctional aspartokinase/homoseri...3709e-77     259     41     61GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
8O81852    916   AKH2_ARATH Bifunctional aspartokinase/homoser...3733e-76     258     39     60GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IDA:TAIR.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
9P44505    815   AKH_HAEIN Bifunctional aspartokinase/homoseri...3366e-56     200     37     57
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
10P00562    810   AK2H_ECOLI Bifunctional aspartokinase/homoser...3706e-54     194     35     55
GO:0004072; F:aspartate kinase activity; IDA:EcoCyc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IDA:EcoCyc.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009090; P:homoserine biosynthetic process; IDA:EcoCyc.::GO:0009089; P:lysine biosynthetic process via diaminopimelate; IDA:EcoCyc.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
11Q89AR4    816   AKH_BUCBP Bifunctional aspartokinase/homoseri...3602e-51     187     33     56
GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
12Q8K9U9    814   AKH_BUCAP Bifunctional aspartokinase/homoseri...3611e-49     181     33     55
GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
13P57290    816   AKH_BUCAI Bifunctional aspartokinase/homoseri...3664e-49     180     32     54
GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
14P27725    819   AK1H_SERMA Bifunctional aspartokinase/homoser...3014e-47     175     36     56
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
15P00561    820   AK1H_ECOLI Bifunctional aspartokinase/homoser...3444e-47     175     34     53
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IDA:EcoCyc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IDA:EcoCyc.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009090; P:homoserine biosynthetic process; IDA:EcoCyc.::GO:0009089; P:lysine biosynthetic process via diaminopimelate; IDA:EcoCyc.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
16P52986    433   DHOM_SYNY3 Homoserine dehydrogenase OS=Synech...2190.000000000000004     79.7     30     50
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
17P08499    445   DHOM_CORGL Homoserine dehydrogenase OS=LMG 37...2220.000000000000007     79     28     48
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
18P52985    428   DHOM_LACLC Homoserine dehydrogenase OS=Lactoc...3570.00000000000001     78.2     24     44
GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
19Q9CGD8    428   DHOM_LACLA Homoserine dehydrogenase OS=lactis...3560.0000000000006     73.2     24     42
GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
20Q58997    336   DHOM_METJA Homoserine dehydrogenase OS=JCM 10...2510.0000000000008     72.4     27     45
GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
21P19582    433   DHOM_BACSU Homoserine dehydrogenase OS=Bacill...2370.00000000001     68.9     27     46
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
22Q9ZL20    421   DHOM_HELPJ Homoserine dehydrogenase OS=Helico...2460.00000000001     68.9     27     46
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
23P56429    421   DHOM_HELPY Homoserine dehydrogenase OS=pylori...3610.00000000002     68.6     24     42
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
24P29365    434   DHOM_PSEAE Homoserine dehydrogenase OS=12228)...2670.0000000002     65.5     27     45
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
25P46806    441   DHOM_MYCLE Homoserine dehydrogenase OS=Mycoba...2570.000000009     60.1     25     45
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
26P37144    412   DHON_METGL Homoserine dehydrogenase OS=Methyl...1240.0000002     56.2     31     52
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
27P63629    441   DHOM_MYCTU Homoserine dehydrogenase OS=Mycoba...2560.000003     52.4     24     44GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
28P63630    441   DHOM_MYCBO Homoserine dehydrogenase OS=Mycoba...2560.000003     52.4     24     44
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
29Q8Y714    371   MNMA_LISMO tRNA-specific 2-thiouridylase MnmA...1550.16     37.4     25     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016783; F:sulfurtransferase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
30P75530    280   Y241_MYCPN Uncharacterized protein MG103 homo...730.31     36.2     32     51
31B8DDZ8    371   MNMA_LISMH tRNA-specific 2-thiouridylase MnmA...1550.45     35.8     24     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016783; F:sulfurtransferase activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
records
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