Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR130C
Length:
639
Number of sequences:
5887
Description:
YJR130C STR2 SGDID:S000003891, Chr X from 667137-665218, Genome Release 64-1-1, reverse complement, Verified ORF, "Cystathionine gamma-synthase, converts cysteine into cystathionine"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P47164    639   MET7_YEAST Cystathionine gamma-synthase OS=Sa...6390     1325     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003962; F:cystathionine gamma-synthase activity; IMP:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0019346; P:transsulfuration; IMP:SGD.
2Q04533    649   METX_YEAST Putative cystathionine gamma-synth...6630     708     55     70GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
3P38675    621   MET7_NEUCR Cystathionine gamma-synthase OS=12...6772e-133     411     38     53
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
4O74314    610   MET7_SCHPO Probable cystathionine gamma-synth...6693e-130     403     37     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0003962; F:cystathionine gamma-synthase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006534; P:cysteine metabolic process; ISS:PomBase.::GO:0019281; P:L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine; ISS:PomBase.
5Q12198    575   METW_YEAST Putative cystathionine gamma-synth...6414e-126     391     37     56
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
6A2RM21    380   METC_LACLM Cystathionine beta-lyase OS=Lactoc...2592e-16     85.1     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
7P0A4K2    380   METC_LACLA Cystathionine beta-lyase OS=lactis...2592e-16     85.1     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
8P0C2T9    380   METC_LACLC Cystathionine beta-lyase OS=Lactoc...2550.000000000000003     81.6     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
9Q1M0P5    380   METB_HELPX Cystathionine gamma-synthase OS=He...2570.000000000000009     80.1     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
10P56069    380   METB_HELPY Cystathionine gamma-synthase OS=py...2570.00000000000002     79     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
11Q9ZMW7    380   METB_HELPJ Cystathionine gamma-synthase OS=He...2570.00000000000002     79     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
12P13254    398   MEGL_PSEPU Methionine gamma-lyase OS=Pseudomo...2820.0000000000005     74.7     27     44
GO:0018826; F:methionine gamma-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
13O05394    379   MCCB_BACSU Cystathionine gamma-lyase OS=Bacil...2590.000000000002     72.8     25     42
GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0047982; F:homocysteine desulfhydrase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
14P00935    386   METB_ECOLI Cystathionine gamma-synthase OS=Es...2680.000000000002     72.8     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IDA:EcoCyc.::GO:0042802; F:identical protein binding; IPI:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IDA:EcoCyc.
GO:0009086; P:methionine biosynthetic process; IMP:EcoCyc.
15O31632    390   METC_BACSU Cystathionine beta-lyase metC OS=B...3710.000000000004     72     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
16P46807    388   METB_MYCLE Cystathionine gamma-synthase OS=My...2550.0000000006     65.5     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
17P31373    394   CYS3_YEAST Cystathionine gamma-lyase OS=Sacch...2590.000000003     62.8     29     48GO:0005737; C:cytoplasm; IDA:SGD.
GO:0004123; F:cystathionine gamma-lyase activity; IDA:SGD.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:SGD.::GO:0019346; P:transsulfuration; IMP:SGD.
18Q55DV9    387   CGL_DICDI Cystathionine gamma-lyase OS=Dictyo...2980.000000008     61.6     26     46GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.
GO:0004123; F:cystathionine gamma-lyase activity; ISS:dictyBase.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
19P38716    378   YHR2_YEAST Uncharacterized trans-sulfuration ...4060.000000008     61.6     23     40GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
20P55217    563   METB_ARATH Cystathionine gamma-synthase, chlo...2500.00000008     58.9     26     46GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0003962; F:cystathionine gamma-synthase activity; IDA:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IMP:TAIR.::GO:0001887; P:selenium compound metabolic process; IDA:TAIR.
21P53780    464   METC_ARATH Cystathionine beta-lyase, chloropl...2550.0000001     58.2     27     45GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0004121; F:cystathionine beta-lyase activity; IMP:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; TAS:TAIR.
22Q8VCN5    398   CGL_MOUSE Cystathionine gamma-lyase OS=Mus mu...2650.0000002     57     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0044524; P:protein sulfhydration; IDA:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.
23Q19QT7    405   CGL_PIG Cystathionine gamma-lyase OS=Sus scro...2590.0000005     56.2     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.
24P66875    388   METB_MYCTU Cystathionine gamma-synthase OS=My...2630.0000006     55.8     26     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0004123; F:cystathionine gamma-lyase activity; IDA:MTBBASE.::GO:0003962; F:cystathionine gamma-synthase activity; IDA:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:MTBBASE.::GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IMP:MTBBASE.
25P66876    388   METB_MYCBO Cystathionine gamma-synthase OS=My...2630.0000006     55.8     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
26O31631    373   METI_BACSU Cystathionine gamma-synthase/O-ace...2530.000001     54.7     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
27Q83A83    387   METC_COXBU Cystathionine beta-lyase OS=Coxiel...2590.000002     54.3     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
28P18757    398   CGL_RAT Cystathionine gamma-lyase OS=Rattus n...2690.000002     53.9     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004121; F:cystathionine beta-lyase activity; IDA:RGD.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0006749; P:glutathione metabolic process; IMP:RGD.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.::GO:0019346; P:transsulfuration; TAS:RGD.
29P55216    392   CGL2_CAEEL Putative cystathionine gamma-lyase...2590.000004     53.1     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.
30P24601    319   METB_HERAU Probable cystathionine gamma-synth...1810.00004     49.7     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
31Q60HG7    405   CGL_MACFA Cystathionine gamma-lyase OS=Macaca...2610.00008     48.9     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.
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