Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR130C
Length:
639
Number of sequences:
5887
Description:
YJR130C STR2 SGDID:S000003891, Chr X from 667137-665218, Genome Release 64-1-1, reverse complement, Verified ORF, "Cystathionine gamma-synthase, converts cysteine into cystathionine"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q60HG7    405   CGL_MACFA Cystathionine gamma-lyase OS=Macaca...2610.00008     48.9     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.
32P44502    369   METB_HAEIN Cystathionine gamma-synthase OS=Ha...2510.00009     48.9     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
33P53101    465   STR3_YEAST Cystathionine beta-lyase OS=Saccha...2720.0001     48.5     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IDA:SGD.
GO:0004121; F:cystathionine beta-lyase activity; IMP:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0071266; P:'de novo' L-methionine biosynthetic process; IEA:InterPro.::GO:0019346; P:transsulfuration; IMP:SGD.
34Q58DW2    405   CGL_BOVIN Cystathionine gamma-lyase OS=Bos ta...2430.0006     46.2     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.
35Q07703    396   METC_BORAV Cystathionine beta-lyase OS=Bordet...2600.0008     45.8     22     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
36O42851    398   YFHE_SCHPO Uncharacterized trans-sulfuration ...2600.002     44.7     25     40
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
37P06106    444   MET17_YEAST Protein MET17 OS=Saccharomyces ce...2940.002     44.7     24     40GO:0005737; C:cytoplasm; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0004124; F:cysteine synthase activity; IDA:SGD.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
38Q59829    392   CYSA_STRCO Putative cystathionine gamma-lyase...2700.002     44.3     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
39O94350    390   CBL_SCHPO Cystathionine beta-lyase OS=Schizos...2590.004     43.9     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; ISS:PomBase.
GO:0004121; F:cystathionine beta-lyase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IC:PomBase.
40O13326    429   CYSD_SCHPO O-acetylhomoserine (thiol)-lyase O...2870.004     43.5     24     40GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004124; F:cysteine synthase activity; ISS:PomBase.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; TAS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
41P95199    406   METZ_MYCTU O-succinylhomoserine sulfhydrylase...3440.014     42     24     38
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0071268; P:homocysteine biosynthetic process; IEA:InterPro.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
42P32929    405   CGL_HUMAN Cystathionine gamma-lyase OS=Homo s...2410.015     41.6     25     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; IDA:UniProtKB.::GO:0047982; F:homocysteine desulfhydrase activity; TAS:Reactome.::GO:0080146; F:L-cysteine desulfhydrase activity; TAS:Reactome.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IMP:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
GO:0019344; P:cysteine biosynthetic process; IDA:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IPI:UniProtKB.::GO:0044524; P:protein sulfhydration; IMP:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; IDA:UniProtKB.::GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.::GO:0019346; P:transsulfuration; TAS:Reactome.
43P55218    403   METZ_PSEAE O-succinylhomoserine sulfhydrylase...2560.053     40     23     39
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0071268; P:homocysteine biosynthetic process; IEA:InterPro.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
44A0PP15    382   HIS8_MYCUA Histidinol-phosphate aminotransfer...1750.13     38.9     24     43
GO:0004400; F:histidinol-phosphate transaminase activity; IEA:EC.::GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
45B2HQA3    382   HIS8_MYCMM Histidinol-phosphate aminotransfer...1750.15     38.5     24     43
GO:0004400; F:histidinol-phosphate transaminase activity; IEA:EC.::GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
46P44527    396   METC_HAEIN Cystathionine beta-lyase OS=Haemop...3770.16     38.5     22     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
47Q3IG30    281   Y2554_PSEHT UPF0042 nucleotide-binding protei...1020.17     38.1     25     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
48Q92441    444   MET17_KLULA Protein MET17 OS=1267 / NRRL Y-11...3030.23     38.1     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
49A0T0R0    732   RPOC1_THAPS DNA-directed RNA polymerase subun...1580.43     37.4     23     39GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
50A0T0D8    696   RPOC1_PHATC DNA-directed RNA polymerase subun...1580.46     37.4     23     39GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
51Q9X7B8    377   HIS8_MYCLE Histidinol-phosphate aminotransfer...1470.87     36.2     25     43
GO:0004400; F:histidinol-phosphate transaminase activity; IEA:EC.::GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
52B8ZRB0    377   HIS8_MYCLB Histidinol-phosphate aminotransfer...1470.87     36.2     25     43
GO:0004400; F:histidinol-phosphate transaminase activity; IEA:EC.::GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
53P09174    87   CNRG_MOUSE Retinal rod rhodopsin-sensitive cG...282.5     32.3     50     68
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IDA:MGI.::GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IDA:MGI.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
54P18545    87   CNRG_HUMAN Retinal rod rhodopsin-sensitive cG...282.5     32.3     50     68GO:0005829; C:cytosol; TAS:Reactome.
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.::GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007601; P:visual perception; TAS:ProtInc.
55P61248    87   CNRG_FELCA Retinal rod rhodopsin-sensitive cG...282.5     32.3     50     68
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
56Q9EQQ8    87   CNRG_CAVPO Retinal rod rhodopsin-sensitive cG...282.5     32.3     50     68
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
57P54827    87   CNRG_CANFA Retinal rod rhodopsin-sensitive cG...282.5     32.3     50     68
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
58P04972    87   CNRG_BOVIN Retinal rod rhodopsin-sensitive cG...282.5     32.3     50     68
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
59P61250    83   CNCG_RAT Retinal cone rhodopsin-sensitive cGM...283.4     32     46     71
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
60P61249    83   CNCG_MOUSE Retinal cone rhodopsin-sensitive c...283.4     32     46     71
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.
GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IDA:MGI.::GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IDA:MGI.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
61Q13956    83   CNCG_HUMAN Retinal cone rhodopsin-sensitive c...283.6     32     46     71
GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:EC.::GO:0030553; F:cGMP binding; IEA:InterPro.::GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; TAS:ProtInc.
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