UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YJR117W

Length:

453

Number of sequences:

5887

Description:

YJR117W STE24 SGDID:S000003878, Chr X from 642007-643368, Genome Release 64-1-1, Verified ORF, "Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P47154	453	STE24_YEAST CAAX prenyl protease 1 OS=Sacchar...	453	0	926	100	100	GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.::GO:0005637; C:nuclear inner membrane; IMP:SGD.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:SGD.
									GO:0071586; P:CAAX-box protein processing; IMP:SGD.::GO:0007323; P:peptide pheromone maturation; IDA:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
2	Q10071	474	STE24_SCHPO Probable CAAX prenyl protease 1 O...	454	3e-109	338	41	62	GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; ISS:PomBase.
									GO:0071586; P:CAAX-box protein processing; ISS:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
3	Q8RX88	424	FACE1_ARATH CAAX prenyl protease 1 homolog OS...	443	2e-105	326	42	58	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005773; C:vacuole; IDA:TAIR.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; ISS:TAIR.
									GO:0080120; P:CAAX-box protein maturation; IDA:TAIR.::GO:0006508; P:proteolysis; IDA:TAIR.
4	Q6EPN8	425	FACE1_ORYSJ CAAX prenyl protease 1 homolog OS...	443	1e-100	314	41	58	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
5	Q54FH7	426	FACE1_DICDI CAAX prenyl protease 1 homolog OS...	430	9e-83	268	37	55	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; ISS:dictyBase.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
6	Q80W54	475	FACE1_MOUSE CAAX prenyl protease 1 homolog OS...	462	6e-80	261	35	53	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:MGI.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:MGI.
									GO:0006998; P:nuclear envelope organization; IMP:MGI.::GO:0030327; P:prenylated protein catabolic process; IDA:MGI.
7	O75844	475	FACE1_HUMAN CAAX prenyl protease 1 homolog OS...	467	1e-79	261	35	52	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008235; F:metalloexopeptidase activity; TAS:ProtInc.
8	P40769	426	YHFN_BACSU Uncharacterized metalloprotease yh...	358	6e-25	109	27	47	GO:0016020; C:membrane; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9	A6SXH1	290	HTPX_JANMA Protease HtpX homolog OS=Janthinob...	233	0.00000000000007	75.1	26	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10	A4G729	293	HTPX_HERAR Protease HtpX homolog OS=Herminiim...	229	0.0000000000005	72.8	26	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11	Q21ST3	291	HTPX_RHOFD Protease HtpX homolog OS=Rhodofera...	225	0.00000000001	68.6	27	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12	A1WH77	292	HTPX_VEREI Protease HtpX homolog OS=Vermineph...	225	0.0000000001	65.9	24	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13	B8FG65	310	HTPX_DESAA Protease HtpX homolog OS=Desulfati...	238	0.0000000001	65.9	24	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14	A4WRW9	299	HTPX_RHOS5 Protease HtpX homolog OS=Rhodobact...	253	0.0000000001	65.5	24	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
15	Q3J0F7	300	HTPX_RHOS4 Protease HtpX homolog OS=158). GN=...	254	0.0000000002	65.5	25	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
16	A3PLU3	300	HTPX_RHOS1 Protease HtpX homolog OS=Rhodobact...	254	0.0000000002	65.5	25	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
17	B1XWS3	291	HTPX_LEPCP Protease HtpX homolog OS=discophor...	229	0.0000000004	64.3	26	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
18	B4S7I8	291	HTPX_PROA2 Protease HtpX homolog OS=Prostheco...	229	0.0000000005	63.9	28	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
19	A9ITD6	293	HTPX_BORPD Protease HtpX homolog OS=Bordetell...	234	0.0000000006	63.5	26	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
20	A1TV68	291	HTPX_ACIAC Protease HtpX homolog OS=citrulli)...	223	0.0000000008	63.2	25	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
21	Q7VWH2	293	HTPX_BORPE Protease HtpX homolog OS=Bordetell...	236	0.000000001	62.8	26	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
22	Q7W7R8	293	HTPX_BORPA Protease HtpX homolog OS=Bordetell...	236	0.000000001	62.8	26	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
23	Q7WL55	293	HTPX_BORBR Protease HtpX homolog OS=(Alcalige...	236	0.000000001	62.8	26	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
24	A1VSW7	291	HTPX_POLNA Protease HtpX homolog OS=Polaromon...	226	0.000000001	62.4	26	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
25	Q65TG9	284	HTPX_MANSM Protease HtpX OS=Mannheimia succin...	239	0.000000002	61.6	26	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
26	Q12EQ7	291	HTPX_POLSJ Protease HtpX homolog OS=Polaromon...	226	0.000000003	61.6	25	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
27	Q13D27	315	HTPX_RHOPS Protease HtpX homolog OS=Rhodopseu...	243	0.000000003	62	24	40	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
28	Q5ZZ31	280	HTPX_LEGPH Protease HtpX OS=ATCC 33152 / DSM ...	268	0.000000003	61.6	26	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
29	Q3SW84	307	HTPX_NITWN Protease HtpX homolog OS=Nitrobact...	243	0.000000003	61.6	25	40	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
30	Q6AMM5	287	HTPX_DESPS Protease HtpX homolog OS=Desulfota...	203	0.000000003	61.6	28	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
31	B2J204	289	HTPX_NOSP7 Protease HtpX homolog OS=Nostoc pu...	241	0.000000003	61.2	24	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.

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