UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YJR099W

Length:

236

Number of sequences:

5887

Description:

YJR099W YUH1 SGDID:S000003860, Chr X from 615576-616286, Genome Release 64-1-1, Verified ORF, "Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P35127	236	UBL1_YEAST Ubiquitin carboxyl-terminal hydrol...	236	4e-174	485	100	100	GO:0005737; C:cytoplasm; IC:SGD.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
2	Q9JKB1	230	UCHL3_MOUSE Ubiquitin carboxyl-terminal hydro...	241	4e-31	119	34	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0007628; P:adult walking behavior; IGI:MGI.::GO:0032869; P:cellular response to insulin stimulus; IDA:UniProtKB.::GO:0042755; P:eating behavior; IGI:MGI.::GO:0045600; P:positive regulation of fat cell differentiation; IDA:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
3	Q91Y78	230	UCHL3_RAT Ubiquitin carboxyl-terminal hydrola...	240	6e-31	119	34	53
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
4	Q2TBG8	230	UCHL3_BOVIN Ubiquitin carboxyl-terminal hydro...	194	1e-30	118	36	56
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
5	P15374	230	UCHL3_HUMAN Ubiquitin carboxyl-terminal hydro...	194	2e-30	118	36	56	GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; TAS:UniProtKB.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
6	Q06AB3	230	UCHL3_PIG Ubiquitin carboxyl-terminal hydrola...	193	1e-29	115	35	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
7	P58321	233	UCHL4_MOUSE Ubiquitin carboxyl-terminal hydro...	243	5e-27	108	33	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
8	O01391	214	UCHL_APLCA Ubiquitin carboxyl-terminal hydrol...	198	1e-26	107	32	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
9	Q54T48	255	UCHL_DICDI Probable ubiquitin carboxyl-termin...	239	6e-26	106	29	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
10	P35122	227	UCHL_DROME Ubiquitin carboxyl-terminal hydrol...	232	1e-22	96.7	31	50	GO:0005875; C:microtubule associated complex; IDA:FlyBase.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:FlyBase.
									GO:0016579; P:protein deubiquitination; IDA:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
11	Q9GM50	223	UCHL1_HORSE Ubiquitin carboxyl-terminal hydro...	210	5e-20	89.4	30	50	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
12	P09936	223	UCHL1_HUMAN Ubiquitin carboxyl-terminal hydro...	184	2e-19	87.8	30	51	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
									GO:0031694; F:alpha-2A adrenergic receptor binding; IPI:BHF-UCL.::GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; TAS:UniProtKB.
									GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
13	Q00981	223	UCHL1_RAT Ubiquitin carboxyl-terminal hydrola...	184	2e-19	87.4	30	51	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0019233; P:sensory perception of pain; IDA:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:RGD.
14	Q9R0P9	223	UCHL1_MOUSE Ubiquitin carboxyl-terminal hydro...	184	2e-19	87.4	30	51	GO:0030424; C:axon; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:MGI.
									GO:0007628; P:adult walking behavior; IMP:MGI.::GO:0007412; P:axon target recognition; IMP:MGI.::GO:0019896; P:axon transport of mitochondrion; IMP:MGI.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0042755; P:eating behavior; IGI:MGI.::GO:0050905; P:neuromuscular process; IMP:MGI.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006950; P:response to stress; IMP:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
15	Q60HC8	223	UCHL1_MACFA Ubiquitin carboxyl-terminal hydro...	184	6e-19	86.3	29	51	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
16	Q6SEG5	223	UCHL1_PIG Ubiquitin carboxyl-terminal hydrola...	184	1e-18	85.5	30	50	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
17	Q10171	222	UBLH1_SCHPO Probable ubiquitin carboxyl-termi...	217	9e-17	80.1	29	50	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
									GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
18	P23356	252	UCHL1_BOVIN Ubiquitin carboxyl-terminal hydro...	213	0.000000000000007	74.7	25	43	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
19	Q54N38	343	UCHL5_DICDI Ubiquitin carboxyl-terminal hydro...	217	0.00000000004	65.1	27	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
20	Q06AT3	329	UCHL5_PIG Ubiquitin carboxyl-terminal hydrola...	225	0.00000002	57	28	43	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
21	Q9XSJ0	328	UCHL5_BOVIN Ubiquitin carboxyl-terminal hydro...	225	0.00000003	57	28	43	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0070628; F:proteasome binding; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
22	Q9Y5K5	329	UCHL5_HUMAN Ubiquitin carboxyl-terminal hydro...	225	0.00000003	57	28	43	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031011; C:Ino80 complex; IDA:UniProtKB.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0004866; F:endopeptidase inhibitor activity; IMP:UniProtKB.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0070628; F:proteasome binding; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
23	Q9WUP7	329	UCHL5_MOUSE Ubiquitin carboxyl-terminal hydro...	216	0.00000004	56.2	29	44	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
									GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0048853; P:forebrain morphogenesis; IMP:BHF-UCL.::GO:0021670; P:lateral ventricle development; IMP:BHF-UCL.::GO:0030901; P:midbrain development; IMP:BHF-UCL.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
24	Q9UUB6	300	UBLH2_SCHPO Ubiquitin carboxyl-terminal hydro...	208	0.00007	46.6	27	44	GO:0034399; C:nuclear periphery; IDA:PomBase.::GO:0000502; C:proteasome complex; IDA:PomBase.
									GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
									GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0071947; P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process; IC:PomBase.
25	Q09444	321	UBH4_CAEEL Probable ubiquitin carboxyl-termin...	244	0.0005	44.3	26	43	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
26	C4A0D9	694	BAP1_BRAFL Ubiquitin carboxyl-terminal hydrol...	193	0.004	41.6	25	41	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0035517; C:PR-DUB complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0035522; P:monoubiquitinated histone H2A deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
27	B4KT51	461	CALYP_DROMO Ubiquitin carboxyl-terminal hydro...	188	0.046	38.1	25	43	GO:0000790; C:nuclear chromatin; ISS:UniProtKB.::GO:0035517; C:PR-DUB complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006342; P:chromatin silencing; ISS:UniProtKB.::GO:0035522; P:monoubiquitinated histone H2A deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
28	B4LQ24	462	CALYP_DROVI Ubiquitin carboxyl-terminal hydro...	188	0.055	38.1	25	43	GO:0000790; C:nuclear chromatin; ISS:UniProtKB.::GO:0035517; C:PR-DUB complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006342; P:chromatin silencing; ISS:UniProtKB.::GO:0035522; P:monoubiquitinated histone H2A deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
29	B4JW98	462	CALYP_DROGR Ubiquitin carboxyl-terminal hydro...	188	0.058	37.7	25	43	GO:0000790; C:nuclear chromatin; ISS:UniProtKB.::GO:0035517; C:PR-DUB complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006342; P:chromatin silencing; ISS:UniProtKB.::GO:0035522; P:monoubiquitinated histone H2A deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
30	B3MIV9	470	CALYP_DROAN Ubiquitin carboxyl-terminal hydro...	190	0.12	37	25	43	GO:0000790; C:nuclear chromatin; ISS:UniProtKB.::GO:0035517; C:PR-DUB complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006342; P:chromatin silencing; ISS:UniProtKB.::GO:0035522; P:monoubiquitinated histone H2A deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
31	Q66JB6	685	BAP1_XENTR Ubiquitin carboxyl-terminal hydrol...	192	0.15	37	23	41	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0035517; C:PR-DUB complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0035522; P:monoubiquitinated histone H2A deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.

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