rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P45376 | 316 | ALDR_MOUSE Aldose reductase OS=Mus musculus (... | 286 | 6e-48 | 167 | 35 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI. | | | | | | | | | | | 32 | A3PXT0 | 276 | Y1919_MYCSJ Uncharacterized oxidoreductase Mj... | 262 | 8e-48 | 166 | 34 | 55 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 33 | P07943 | 316 | ALDR_RAT Aldose reductase OS=Rattus norvegicu... | 286 | 1e-47 | 167 | 34 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:RGD. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:RGD. | | | | | | | | | | GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0010033; P:response to organic substance; IDA:RGD.::GO:0006061; P:sorbitol biosynthetic process; IMP:RGD.::GO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD. | 34 | P15122 | 316 | ALDR_RABIT Aldose reductase OS=Oryctolagus cu... | 285 | 1e-47 | 167 | 36 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 35 | Q8X195 | 321 | XYL1_CANBO NADPH-dependent D-xylose reductase... | 307 | 1e-47 | 167 | 35 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 36 | P45377 | 316 | ALD2_MOUSE Aldose reductase-related protein 2... | 286 | 4e-47 | 166 | 36 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 37 | A1UEC6 | 276 | Y1985_MYCSK Uncharacterized oxidoreductase Mk... | 262 | 4e-47 | 164 | 34 | 55 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | Q8VCX1 | 325 | AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogen... | 291 | 7e-47 | 165 | 35 | 56 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 39 | P51652 | 323 | AKC1H_RAT Aldo-keto reductase family 1 member... | 295 | 8e-47 | 165 | 33 | 55 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0050810; P:regulation of steroid biosynthetic process; IDA:RGD. | 40 | Q8VC28 | 323 | AK1CD_MOUSE Aldo-keto reductase family 1 memb... | 292 | 1e-46 | 164 | 35 | 55 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006805; P:xenobiotic metabolic process; TAS:MGI. | 41 | P17264 | 324 | CRO_LITCT Rho crystallin OS=Lithobates catesb... | 294 | 1e-46 | 164 | 34 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW. | | | | | | | | | | | 42 | P15121 | 316 | ALDR_HUMAN Aldose reductase OS=Homo sapiens (... | 285 | 1e-46 | 164 | 35 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0043795; F:glyceraldehyde oxidoreductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.::GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.::GO:0006950; P:response to stress; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 43 | O80944 | 311 | AKRC8_ARATH Aldo-keto reductase family 4 memb... | 286 | 2e-46 | 164 | 35 | 56 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:UniProtKB.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB. | 44 | P80276 | 316 | ALDR_PIG Aldose reductase OS=Sus scrofa (Pig)... | 286 | 2e-46 | 164 | 37 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 45 | P51857 | 326 | AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogen... | 289 | 2e-46 | 164 | 34 | 55 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.::GO:0005496; F:steroid binding; TAS:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB. | 46 | A3PXS9 | 283 | Y1918_MYCSJ Uncharacterized oxidoreductase Mj... | 263 | 2e-46 | 162 | 33 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 47 | P21300 | 316 | ALD1_MOUSE Aldose reductase-related protein 1... | 285 | 3e-46 | 163 | 35 | 53 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:MGI. | 48 | Q96JD6 | 320 | AKCL2_HUMAN 1,5-anhydro-D-fructose reductase ... | 290 | 5e-46 | 163 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 49 | O94735 | 317 | XYL1_PICGU NADPH-dependent D-xylose reductase... | 312 | 1e-45 | 162 | 33 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW. | 50 | Q4R802 | 320 | AKCL2_MACFA 1,5-anhydro-D-fructose reductase ... | 290 | 1e-45 | 162 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 51 | P51635 | 325 | AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=... | 290 | 2e-45 | 161 | 33 | 54 | | | | | | | | | | | | | | | | | | | | | | 52 | P14550 | 325 | AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] O... | 290 | 2e-45 | 161 | 33 | 55 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc. | 53 | O08782 | 316 | ALD2_CRIGR Aldose reductase-related protein 2... | 286 | 2e-45 | 161 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 54 | P02532 | 324 | CRO_RANTE Rho crystallin OS=Rana temporaria (... | 294 | 3e-45 | 160 | 33 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW. | | | | | | | | | | | 55 | Q0PGJ6 | 315 | AKRC9_ARATH Aldo-keto reductase family 4 memb... | 275 | 4e-45 | 160 | 35 | 55 | GO:0009507; C:chloroplast; IDA:TAIR. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB. | 56 | P23457 | 322 | DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase... | 295 | 6e-45 | 160 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC. | | | | | | | | | | GO:0021766; P:hippocampus development; IEP:RGD.::GO:0008202; P:steroid metabolic process; TAS:RGD. | 57 | A1UEC5 | 283 | Y1984_MYCSK Uncharacterized oxidoreductase Mk... | 263 | 6e-45 | 159 | 32 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 58 | Q1BAN7 | 283 | Y1938_MYCSS Uncharacterized oxidoreductase Mm... | 263 | 6e-45 | 159 | 32 | 54 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 59 | Q91WR5 | 323 | AK1CL_MOUSE Aldo-keto reductase family 1 memb... | 291 | 7e-45 | 160 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033764; F:steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IDA:MGI. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 60 | Q5RJP0 | 316 | ALD1_RAT Aldose reductase-related protein 1 O... | 285 | 1e-44 | 159 | 34 | 53 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:RGD. | | | | | | | | | | | 61 | P50578 | 325 | AK1A1_PIG Alcohol dehydrogenase [NADP(+)] OS=... | 288 | 1e-44 | 159 | 31 | 56 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | |