Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR078W
Length:
453
Number of sequences:
5887
Description:
YJR078W BNA2 SGDID:S000003839, Chr X from 578860-580221, Genome Release 64-1-1, Verified ORF, "Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for de novo biosynthesis of NAD from tryptophan via kynurenine; interacts genetically with telomere capping gene CDC13; regulated by Hst1p and Aftp"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P47125    453   I23O_YEAST Indoleamine 2,3-dioxygenase family...4530     945     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; NAS:SGD.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; NAS:SGD.
GO:0034354; P:de novo NAD biosynthetic process from tryptophan; IGI:SGD.
2Q9ERD9    407   I23O1_RAT Indoleamine 2,3-dioxygenase 1 OS=Ra...4236e-54     191     32     50GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0016597; F:amino acid binding; IDA:RGD.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:RGD.::GO:0019825; F:oxygen binding; IDA:RGD.
GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:RGD.
3Q6ZQW0    407   I23O2_HUMAN Indoleamine 2,3-dioxygenase 2 OS=...4273e-53     189     33     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:UniProtKB.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome.
GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:UniProtKB.
4P28776    407   I23O1_MOUSE Indoleamine 2,3-dioxygenase 1 OS=...4256e-53     188     33     50GO:0030485; C:smooth muscle contractile fiber; IDA:MGI.::GO:0032421; C:stereocilium bundle; IDA:MGI.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; IDA:MGI.
GO:0007610; P:behavior; IMP:MGI.::GO:0002534; P:cytokine production involved in inflammatory response; IMP:MGI.::GO:0034276; P:kynurenic acid biosynthetic process; IMP:MGI.::GO:0033555; P:multicellular organismal response to stress; IMP:MGI.::GO:0046007; P:negative regulation of activated T cell proliferation; IMP:MGI.::GO:0032693; P:negative regulation of interleukin-10 production; IMP:MGI.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002678; P:positive regulation of chronic inflammatory response; IMP:MGI.::GO:0032735; P:positive regulation of interleukin-12 production; IMP:MGI.::GO:0002666; P:positive regulation of T cell tolerance induction; IMP:MGI.::GO:0002830; P:positive regulation of type 2 immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.::GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:MGI.
5Q8R0V5    398   I23O2_MOUSE Indoleamine 2,3-dioxygenase 2 OS=...4246e-52     185     32     50
GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.
6P14902    403   I23O1_HUMAN Indoleamine 2,3-dioxygenase 1 OS=...3962e-48     176     32     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome.
GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
7P51537    378   MYG_HALMK Myoglobin OS=Haliotis madaka (Giant...4262e-41     156     29     44
GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
8Q01966    378   MYG_HALDV Myoglobin OS=Haliotis diversicolor ...4246e-40     152     30     44
GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
9Q08D88    462   NFIL3_BOVIN Nuclear factor interleukin-3-regu...810.99     35.4     26     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007623; P:circadian rhythm; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10P47827    415   CCNA2_XENLA Cyclin-A2 OS=Xenopus laevis (Afri...1311.3     35     24     40GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
11Q058F3    550   CH60_BUCCC 60 kDa chaperonin OS=Buchnera aphi...624.3     33.5     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0042026; P:protein refolding; IEA:InterPro.
12Q8KIX3    547   CH60_BUCTC 60 kDa chaperonin OS=Buchnera aphi...424.8     33.5     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0042026; P:protein refolding; IEA:InterPro.
records
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