Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR066W
Length:
2470
Number of sequences:
5887
Description:
YJR066W TOR1 SGDID:S000003827, Chr X from 559416-566828, Genome Release 64-1-1, Verified ORF, "PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q22258    2531   ATR_CAEEL Serine/threonine-protein kinase ATR...4095e-23     112     25     42GO:0000794; C:condensed nuclear chromosome; TAS:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.
62Q9Y4A5    3859   TRRAP_HUMAN Transformation/transcription doma...6724e-16     89.7     23     40GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:UniProtKB.::GO:0000125; C:PCAF complex; NAS:UniProtKB.::GO:0030914; C:STAGA complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
63Q80YV3    2565   TRRAP_MOUSE Transformation/transcription doma...5260.00000000000002     84     24     41GO:0035267; C:NuA4 histone acetyltransferase complex; ISS:UniProtKB.
GO:0005488; F:binding; IEA:InterPro.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
GO:0043968; P:histone H2A acetylation; ISS:UniProtKB.::GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
64Q10064    3655   YAMB_SCHPO Uncharacterized PI3/PI4-kinase fam...2708.5     35.4     25     38GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:PomBase.
GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0006281; P:DNA repair; ISS:PomBase.::GO:0016573; P:histone acetylation; IC:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IC:PomBase.
65O35904    1043   PK3CD_MOUSE Phosphatidylinositol 4,5-bisphosp...2850.00000000003     72.8     27     44GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.
GO:0042113; P:B cell activation; IMP:MGI.::GO:0001782; P:B cell homeostasis; IMP:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007166; P:cell surface receptor signaling pathway; IMP:MGI.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
66O00329    1044   PK3CD_HUMAN Phosphatidylinositol 4,5-bisphosp...2850.00000000008     71.6     26     42GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.
GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0035754; P:B cell chemotaxis; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0001816; P:cytokine production; TAS:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0002551; P:mast cell chemotaxis; TAS:UniProtKB.::GO:0043303; P:mast cell degranulation; TAS:UniProtKB.::GO:0060374; P:mast cell differentiation; TAS:UniProtKB.::GO:0035747; P:natural killer cell chemotaxis; TAS:UniProtKB.::GO:0001779; P:natural killer cell differentiation; TAS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.::GO:0072672; P:neutrophil extravasation; TAS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0006468; P:protein phosphorylation; NAS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; TAS:UniProtKB.::GO:0010818; P:T cell chemotaxis; TAS:UniProtKB.::GO:0030217; P:T cell differentiation; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:UniProtKB.
67P42347    814   PI3K1_SOYBN Phosphatidylinositol 3-kinase, ro...2770.0000000004     69.3     26     42GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
68Q6AZN6    886   PK3C3_XENLA Phosphatidylinositol 3-kinase cat...2270.0000000005     68.9     26     40GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
69P38811    3744   TRA1_YEAST Transcription-associated protein 1...3390.0000000006     69.3     23     42GO:0070209; C:ASTRA complex; IDA:SGD.::GO:0035267; C:NuA4 histone acetyltransferase complex; IPI:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006281; P:DNA repair; IDA:SGD.::GO:0016573; P:histone acetylation; IDA:GOC.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
70P42348    812   PI3K2_SOYBN Phosphatidylinositol 3-kinase, no...2910.0000000006     68.6     25     41GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
71P22543    875   VPS34_YEAST Phosphatidylinositol 3-kinase VPS...3480.000000001     67.8     28     41GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IDA:SGD.::GO:0034271; C:phosphatidylinositol 3-kinase complex I; IDA:SGD.::GO:0034272; C:phosphatidylinositol 3-kinase complex II; IDA:SGD.::GO:0000407; C:pre-autophagosomal structure; IDA:SGD.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IDA:SGD.
GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
72Q8BTI9    1064   PK3CB_MOUSE Phosphatidylinositol 4,5-bisphosp...2660.000000003     66.6     27     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IPI:MGI.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0040016; P:embryonic cleavage; IMP:MGI.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007156; P:homophilic cell adhesion; IMP:MGI.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0030168; P:platelet activation; IMP:MGI.::GO:0001952; P:regulation of cell-matrix adhesion; IMP:MGI.
73Q6PF93    887   PK3C3_MOUSE Phosphatidylinositol 3-kinase cat...2280.000000003     66.2     28     44GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IMP:MGI.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.
74Q9Z1L0    1070   PK3CB_RAT Phosphatidylinositol 4,5-bisphospha...2660.000000005     65.9     27     42GO:0031526; C:brush border membrane; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IDA:RGD.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
75O88763    887   PK3C3_RAT Phosphatidylinositol 3-kinase catal...2300.000000006     65.5     28     43GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.
GO:0000045; P:autophagic vacuole assembly; IMP:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; IMP:RGD.::GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:RGD.::GO:0016485; P:protein processing; IMP:RGD.::GO:0050708; P:regulation of protein secretion; IMP:RGD.::GO:0043201; P:response to leucine; IEP:RGD.
76P42338    1070   PK3CB_HUMAN Phosphatidylinositol 4,5-bisphosp...2660.00000001     64.7     27     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:ProtInc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.
GO:0000187; P:activation of MAPK activity; TAS:ProtInc.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0070527; P:platelet aggregation; TAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; TAS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
77Q5D891    887   PK3C3_PIG Phosphatidylinositol 3-kinase catal...2280.00000001     64.3     28     44GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
78Q8NEB9    887   PK3C3_HUMAN Phosphatidylinositol 3-kinase cat...2280.00000001     64.3     28     44GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
79P54675    1697   PI3K3_DICDI Phosphatidylinositol 3-kinase 3 O...2900.00000002     63.9     26     40GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006928; P:cellular component movement; IGI:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
80Q9UW24    956   PIK1A_CANAL Phosphatidylinositol 4-kinase PIK...2770.00000002     63.5     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0044011; P:single-species biofilm formation on inanimate substrate; IMP:CGD.
81P54676    816   PI3K4_DICDI Phosphatidylinositol 3-kinase VPS...2870.00000003     63.2     26     40GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
82Q5UR69    701   YL615_MIMIV Putative phosphatidylinositol kin...2160.00000006     62     25     42
GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
83Q9UW20    977   PIK1_CANAL Phosphatidylinositol 4-kinase PIK1...1420.00000008     61.6     30     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
84Q8SQY7    1433   STT4_ENCCU Probable phosphatidylinositol 4-ki...2400.00000008     62     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro.
GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
85Q8I8U7    3803   TRA1_DROME Transcription-associated protein 1...606.1     36.2     35     58GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:UniProtKB.::GO:0005703; C:polytene chromosome puff; IDA:FlyBase.::GO:0000124; C:SAGA complex; IDA:FlyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0016573; P:histone acetylation; IDA:UniProtKB.::GO:0043486; P:histone exchange; IDA:UniProtKB.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IGI:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IDA:UniProtKB.::GO:0035222; P:wing disc pattern formation; IGI:FlyBase.
86O00443    1686   P3C2A_HUMAN Phosphatidylinositol 4-phosphate ...2320.0000002     60.8     25     42GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:ProtInc.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0048268; P:clathrin coat assembly; TAS:UniProtKB.::GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.::GO:0006887; P:exocytosis; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; TAS:UniProtKB.::GO:0014829; P:vascular smooth muscle contraction; TAS:UniProtKB.
87Q61194    1686   P3C2A_MOUSE Phosphatidylinositol 4-phosphate ...2320.0000002     60.5     25     42GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:MGI.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
88Q5RAY1    1685   P3C2A_PONAB Phosphatidylinositol 4-phosphate ...2320.0000002     60.5     25     42GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:InterPro.::GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
89P42336    1068   PK3CA_HUMAN Phosphatidylinositol 4,5-bisphosp...2300.0000005     59.3     26     44
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; TAS:Reactome.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0060048; P:cardiac muscle contraction; TAS:UniProtKB.::GO:0043542; P:endothelial cell migration; TAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0038028; P:insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
90P32871    1068   PK3CA_BOVIN Phosphatidylinositol 4,5-bisphosp...2300.0000005     59.3     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
91P42337    1068   PK3CA_MOUSE Phosphatidylinositol 4,5-bisphosp...2300.0000005     58.9     26     44GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005942; C:phosphatidylinositol 3-kinase complex; IPI:MGI.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IPI:MGI.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:EC.::GO:0030295; F:protein kinase activator activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0044029; P:hypomethylation of CpG island; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0043491; P:protein kinase B signaling cascade; IMP:MGI.::GO:2000653; P:regulation of genetic imprinting; IDA:BHF-UCL.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.
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