Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR060W
Length:
351
Number of sequences:
5887
Description:
YJR060W CBF1 SGDID:S000003821, Chr X from 548759-549814, Genome Release 64-1-1, Verified ORF, "Dual function helix-loop-helix protein; binds the motif CACRTG present at several sites including MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins and required for efficient chromosome segregation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P17106    351   CBF1_YEAST Centromere-binding protein 1 OS=Sa...3510     716     100     100GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0019237; F:centromeric DNA binding; IDA:SGD.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IMP:SGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:SGD.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IDA:SGD.::GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IMP:SGD.
GO:0006338; P:chromatin remodeling; IDA:SGD.::GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0006021; P:inositol biosynthetic process; IMP:SGD.::GO:0009086; P:methionine biosynthetic process; IMP:SGD.::GO:2000303; P:regulation of ceramide biosynthetic process; IMP:SGD.::GO:0061432; P:regulation of transcription from RNA polymerase II promoter in response to methionine; IMP:SGD.::GO:0000103; P:sulfate assimilation; IMP:SGD.
2P49379    359   CBF1_KLULA Centromere-binding protein 1 OS=12...1183e-41     153     68     82GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
3Q10186    201   YAWC_SCHPO Uncharacterized bHLH domain-contai...1062e-16     80.5     41     64GO:0005634; C:nucleus; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:PomBase.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:PomBase.
4Q07957    307   USF1_XENBO Upstream stimulatory factor 1 OS=X...1140.00003     48.9     36     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q6XBT4    310   USF1_BOVIN Upstream stimulatory factor 1 OS=B...1140.0003     45.4     33     53
6Q15853    346   USF2_HUMAN Upstream stimulatory factor 2 OS=H...600.0004     45.4     40     62GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0019086; P:late viral mRNA transcription; IC:BHF-UCL.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q63665    346   USF2_RAT Upstream stimulatory factor 2 OS=Rat...600.0004     45.4     40     62GO:0005634; C:nucleus; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IMP:RGD.::GO:0042803; F:protein homodimerization activity; IMP:RGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:RGD.
8Q64705    346   USF2_MOUSE Upstream stimulatory factor 2 OS=M...600.0004     45.4     40     62GO:0005634; C:nucleus; IDA:MGI.
GO:0007595; P:lactation; IMP:MGI.::GO:0055088; P:lipid homeostasis; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.
9O02818    310   USF1_RABIT Upstream stimulatory factor 1 OS=O...820.0004     45.4     37     55
10P22415    310   USF1_HUMAN Upstream stimulatory factor 1 OS=H...600.0005     45.1     43     63GO:0005667; C:transcription factor complex; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0042593; P:glucose homeostasis; TAS:BHF-UCL.::GO:0019086; P:late viral mRNA transcription; IDA:BHF-UCL.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0051918; P:negative regulation of fibrinolysis; IC:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0001666; P:response to hypoxia; IMP:BHF-UCL.::GO:0009411; P:response to UV; ISS:BHF-UCL.
11Q61069    310   USF1_MOUSE Upstream stimulatory factor 1 OS=M...600.0006     44.7     43     63GO:0005667; C:transcription factor complex; IC:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0055088; P:lipid homeostasis; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0009411; P:response to UV; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q39204    623   RAP1_ARATH Transcription factor MYC2 OS=Arabi...880.002     43.5     32     55GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009963; P:positive regulation of flavonoid biosynthetic process; IEP:TAIR.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:TAIR.::GO:2000068; P:regulation of defense response to insect; IMP:TAIR.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IMP:TAIR.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IMP:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.::GO:0009269; P:response to desiccation; IEP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13O88368    110   MITF_RAT Microphthalmia-associated transcript...560.002     40.8     41     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
14Q05B92    573   TFE3_BOVIN Transcription factor E3 OS=Bos tau...590.004     42.7     42     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0006959; P:humoral immune response; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15P19532    575   TFE3_HUMAN Transcription factor E3 OS=Homo sa...590.004     42.7     42     61GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0006959; P:humoral immune response; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16P19484    476   TFEB_HUMAN Transcription factor EB OS=Homo sa...580.006     42     40     62GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0001892; P:embryonic placenta development; ISS:UniProtKB.::GO:0006959; P:humoral immune response; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q9R210    475   TFEB_MOUSE Transcription factor EB OS=Mus mus...580.006     42     40     62GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0001892; P:embryonic placenta development; IMP:UniProtKB.::GO:0006959; P:humoral immune response; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q64092    572   TFE3_MOUSE Transcription factor E3 OS=Mus mus...570.006     42     40     58GO:0005667; C:transcription factor complex; IC:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0006959; P:humoral immune response; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045670; P:regulation of osteoclast differentiation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19O75030    526   MITF_HUMAN Microphthalmia-associated transcri...560.007     42     41     57GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
GO:0030318; P:melanocyte differentiation; NAS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.
20P52161    165   MAX_DANRE Protein max OS=Danio rerio (Zebrafi...1200.007     40.4     28     45GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q07956    265   USF_STRPU Upstream stimulatory factor OS=Stro...570.009     40.8     39     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22Q08874    526   MITF_MOUSE Microphthalmia-associated transcri...560.009     41.6     41     57GO:0005634; C:nucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0046849; P:bone remodeling; IMP:MGI.::GO:0043010; P:camera-type eye development; IGI:MGI.::GO:0045165; P:cell fate commitment; IMP:MGI.::GO:0030318; P:melanocyte differentiation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0030316; P:osteoclast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0042127; P:regulation of cell proliferation; IDA:MGI.::GO:0045670; P:regulation of osteoclast differentiation; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IDA:MGI.
23Q9ZPY8    566   AIB_ARATH Transcription factor ABA-INDUCIBLE ...720.01     41.6     33     56GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009611; P:response to wounding; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q68DE3    2245   K2018_HUMAN Basic helix-loop-helix domain-con...600.01     41.6     37     60GO:0016020; C:membrane; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:InterPro.
25Q9FIP9    592   ATR2_ARATH Transcription factor ATR2 OS=Arabi...860.012     41.2     34     52GO:0005634; C:nucleus; IDA:TAIR.
GO:0043425; F:bHLH transcription factor binding; IPI:TAIR.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0009718; P:anthocyanin biosynthetic process; IMP:TAIR.::GO:0006952; P:defense response; IMP:TAIR.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26O61734    413   CYCL_DROME Protein cycle OS=Drosophila melano...620.014     40.8     35     63GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro.
GO:0003677; F:DNA binding; IDA:FlyBase.::GO:0046982; F:protein heterodimerization activity; IPI:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0048148; P:behavioral response to cocaine; NAS:FlyBase.::GO:0032922; P:circadian regulation of gene expression; IMP:FlyBase.::GO:0008062; P:eclosion rhythm; NAS:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; NAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; NAS:FlyBase.::GO:0045187; P:regulation of circadian sleep/wake cycle, sleep; IMP:FlyBase.::GO:0042594; P:response to starvation; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q700C7    364   SPCH_ARATH Transcription factor SPEECHLESS OS...550.014     40.8     38     60GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0010374; P:stomatal complex development; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28O49687    589   BH004_ARATH Transcription factor MYC4 OS=Arab...710.015     40.8     35     54GO:0005634; C:nucleus; IDA:TAIR.
GO:0043425; F:bHLH transcription factor binding; IPI:TAIR.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0009718; P:anthocyanin biosynthetic process; IMP:TAIR.::GO:0006952; P:defense response; IMP:TAIR.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29P38165    486   RTG3_YEAST Retrograde regulation protein 3 OS...820.021     40.4     34     46GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0001085; F:RNA polymerase II transcription factor binding; IPI:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.
GO:0071400; P:cellular response to oleic acid; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IDA:SGD.::GO:0000422; P:mitochondrion degradation; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0042991; P:transcription factor import into nucleus; IMP:SGD.
30Q56YJ8    414   FAMA_ARATH Transcription factor FAMA OS=Arabi...850.026     40     29     59GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0010052; P:guard cell differentiation; IMP:TAIR.::GO:0051782; P:negative regulation of cell division; IMP:TAIR.::GO:0045597; P:positive regulation of cell differentiation; IMP:TAIR.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31Q9DG12    737   ARNT2_DANRE Aryl hydrocarbon receptor nuclear...770.037     39.7     29     49GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; NAS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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