Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR060W
Length:
351
Number of sequences:
5887
Description:
YJR060W CBF1 SGDID:S000003821, Chr X from 548759-549814, Genome Release 64-1-1, Verified ORF, "Dual function helix-loop-helix protein; binds the motif CACRTG present at several sites including MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins and required for efficient chromosome segregation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q7XHI7    307   BH127_ARATH Transcription factor bHLH127 OS=A...451.7     33.9     40     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92P18444    441   MYCN_CHICK N-myc proto-oncogene protein OS=Ga...981.7     34.3     31     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
93Q01664    338   TFAP4_HUMAN Transcription factor AP-4 OS=Homo...811.8     33.9     32     54GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0070888; F:E-box binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:UniProtKB.::GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.::GO:0071157; P:negative regulation of cell cycle arrest; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IDA:UniProtKB.
94Q9CAA4    311   BIM2_ARATH Transcription factor BIM2 OS=Arabi...511.8     33.9     33     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
95Q0JXE7    343   BPE_ARATH Transcription factor BPE OS=Arabido...581.9     33.9     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0048446; P:petal morphogenesis; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
96Q93W88    286   BH137_ARATH Transcription factor bHLH137 OS=A...722     33.9     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009739; P:response to gibberellin stimulus; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
97Q9FMB6    298   BIM3_ARATH Transcription factor BIM3 OS=Arabi...502     33.9     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
98Q17103    407   MYC_ASTRU Myc protein OS=Asterias rubens (Com...582.1     33.9     29     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
99P97831    160   TWST2_RAT Twist-related protein 2 OS=Rattus n...802.3     32.7     34     53GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.
100Q8WVJ9    160   TWST2_HUMAN Twist-related protein 2 OS=Homo s...802.3     32.7     34     53GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0045668; P:negative regulation of osteoblast differentiation; IDA:UniProtKB.
101P23999    429   MYCS_RAT Protein S-Myc OS=Rattus norvegicus (...612.5     33.5     34     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
102A6NFD8    327   HELT_HUMAN Hairy and enhancer of split-relate...452.7     33.5     33     58
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
103Q3U1N2    1130   SRBP2_MOUSE Sterol regulatory element-binding...722.8     33.9     28     58GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0035104; P:positive regulation of transcription via sterol regulatory element binding; IDA:MGI.::GO:2000188; P:regulation of cholesterol homeostasis; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
104Q12772    1141   SRBP2_HUMAN Sterol regulatory element-binding...722.9     33.9     28     58GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0032937; C:SREBP-SCAP-Insig complex; IDA:UniProtKB.
GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
GO:0071499; P:cellular response to laminar fluid shear stress; NAS:BHF-UCL.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0090370; P:negative regulation of cholesterol efflux; IDA:BHF-UCL.::GO:0010886; P:positive regulation of cholesterol storage; IDA:BHF-UCL.::GO:0072368; P:regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0055098; P:response to low-density lipoprotein particle stimulus; IEP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105Q60429    1139   SRBP2_CRIGR Sterol regulatory element-binding...722.9     33.9     28     58GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106O14503    412   BHE40_HUMAN Class E basic helix-loop-helix pr...972.9     33.5     28     48GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0043426; F:MRF binding; ISS:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
GO:0032922; P:circadian regulation of gene expression; IDA:BHF-UCL.::GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
107Q3T1I5    1133   SRBP2_RAT Sterol regulatory element-binding p...722.9     33.5     28     58GO:0030425; C:dendrite; IDA:RGD.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0003682; F:chromatin binding; IDA:RGD.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
GO:0007568; P:aging; IEP:RGD.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; TAS:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IMP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0007283; P:spermatogenesis; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
108Q5RAI7    412   BHE40_PONAB Class E basic helix-loop-helix pr...973     33.5     28     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
109O80536    524   PIF3_ARATH Transcription factor PIF3 OS=Arabi...463     33.5     39     61GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009704; P:de-etiolation; IMP:TAIR.::GO:0009740; P:gibberellic acid mediated signaling pathway; IMP:TAIR.::GO:0031539; P:positive regulation of anthocyanin metabolic process; IMP:TAIR.::GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
110A3KNA7    1099   SRBP2_DANRE Sterol regulatory element-binding...783     33.5     27     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111Q9C0J9    482   BHE41_HUMAN Class E basic helix-loop-helix pr...783.2     33.5     31     45GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; ISS:BHF-UCL.::GO:0043426; F:MRF binding; ISS:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.
GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0010832; P:negative regulation of myotube differentiation; ISS:BHF-UCL.::GO:0010944; P:negative regulation of transcription by competitive promoter binding; ISS:BHF-UCL.::GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
112P0CB25    256   BH131_ARATH Transcription factor bHLH131 OS=A...683.4     32.7     32     49GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
113P12525    357   MYCL2_HUMAN Protein L-Myc-2 OS=Homo sapiens (...643.5     33.1     36     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
114Q9LEZ3    529   BIM1_ARATH Transcription factor BIM1 OS=Arabi...513.6     33.1     37     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:TAIR.
GO:0009742; P:brassinosteroid mediated signaling pathway; IGI:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
115Q9LET0    230   BH107_ARATH Putative transcription factor bHL...543.8     32.7     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
116Q8WYA1    636   BMAL2_HUMAN Aryl hydrocarbon receptor nuclear...563.9     33.1     30     57GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0007623; P:circadian rhythm; IDA:MGI.::GO:0009649; P:entrainment of circadian clock; NAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
117O35779    410   BHE41_RAT Class E basic helix-loop-helix prot...344     33.1     44     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0009649; P:entrainment of circadian clock; IDA:RGD.::GO:0007399; P:nervous system development; NAS:RGD.::GO:0048168; P:regulation of neuronal synaptic plasticity; IEP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118Q99PV5    410   BHE41_MOUSE Class E basic helix-loop-helix pr...344     33.1     44     62GO:0017053; C:transcriptional repressor complex; TAS:MGI.
GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IDA:BHF-UCL.::GO:0043426; F:MRF binding; IDA:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IDA:BHF-UCL.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0003714; F:transcription corepressor activity; TAS:MGI.
GO:0032922; P:circadian regulation of gene expression; IMP:BHF-UCL.::GO:0010832; P:negative regulation of myotube differentiation; IDA:BHF-UCL.::GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.
119Q700E4    358   BH067_ARATH Transcription factor bHLH67 OS=Ar...574.1     32.7     32     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
120Q8QGQ7    622   BMAL2_CHICK Aryl hydrocarbon receptor nuclear...564.6     33.1     30     57GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005667; C:transcription factor complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121Q6NKN9    366   BH074_ARATH Transcription factor bHLH74 OS=Ar...584.8     32.7     33     55GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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