Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR040W
Length:
779
Number of sequences:
5887
Description:
YJR040W GEF1 SGDID:S000003801, Chr X from 507746-510085, Genome Release 64-1-1, Verified ORF, "Voltage-gated chloride channel localized to the golgi, the endosomal system, and plasma membrane, and involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P37020    779   GEF1_YEAST Protein GEF1 OS=Saccharomyces cere...7790     1603     100     100GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.::GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005768; C:endosome; IDA:SGD.::GO:0000324; C:fungal-type vacuole; IDA:SGD.::GO:0005797; C:Golgi medial cisterna; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005247; F:voltage-gated chloride channel activity; IDA:SGD.
GO:0006878; P:cellular copper ion homeostasis; IMP:SGD.::GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.
2P0C197    1131   CLCNX_USTMA Probable chloride channel protein...380.34     38.1     39     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
3Q9TTU3    746   CLCN5_RABIT H(+)/Cl(-) exchange transporter 5...7498e-110     358     33     54GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
GO:0006897; P:endocytosis; ISS:AgBase.
4O60159    812   YHYB_SCHPO Uncharacterized chloride channel p...6983e-109     358     37     53GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.::GO:0005768; C:endosome; ISS:PomBase.::GO:0005794; C:Golgi apparatus; ISS:PomBase.
GO:0005247; F:voltage-gated chloride channel activity; ISS:PomBase.
GO:0030003; P:cellular cation homeostasis; ISS:PomBase.
5P51794    747   CLCN4_RAT H(+)/Cl(-) exchange transporter 4 O...7582e-108     354     33     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
6P51793    760   CLCN4_HUMAN H(+)/Cl(-) exchange transporter 4...7581e-107     353     33     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; TAS:ProtInc.
7Q9WVD4    746   CLCN5_MOUSE H(+)/Cl(-) exchange transporter 5...7541e-107     352     33     53GO:0045177; C:apical part of cell; IDA:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IMP:MGI.
8Q61418    747   CLCN4_MOUSE H(+)/Cl(-) exchange transporter 4...7581e-107     352     33     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
9P51796    746   CLCN5_RAT H(+)/Cl(-) exchange transporter 5 O...7613e-107     351     33     53GO:0045177; C:apical part of cell; ISS:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IDA:RGD.
10Q99P66    746   CLCN5_CAVPO H(+)/Cl(-) exchange transporter 5...7615e-107     350     32     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
11Q9R279    760   CLCN3_CAVPO H(+)/Cl(-) exchange transporter 3...7597e-107     350     32     53GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0005247; F:voltage-gated chloride channel activity; ISS:UniProtKB.
12P51791    818   CLCN3_MOUSE H(+)/Cl(-) exchange transporter 3...7567e-107     352     32     53GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0005247; F:voltage-gated chloride channel activity; ISS:UniProtKB.
13P51792    818   CLCN3_RAT H(+)/Cl(-) exchange transporter 3 O...7567e-107     352     32     53GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IDA:RGD.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0005247; F:voltage-gated chloride channel activity; IDA:UniProtKB.
14O18894    818   CLCN3_RABIT H(+)/Cl(-) exchange transporter 3...7591e-106     352     32     53GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0005247; F:voltage-gated chloride channel activity; ISS:UniProtKB.
15P51790    818   CLCN3_HUMAN H(+)/Cl(-) exchange transporter 3...7591e-106     352     32     53GO:0009986; C:cell surface; NAS:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.::GO:0005247; F:voltage-gated chloride channel activity; TAS:ProtInc.
GO:0048388; P:endosomal lumen acidification; TAS:UniProtKB.
16Q9GKE7    746   CLCN5_PIG H(+)/Cl(-) exchange transporter 5 O...7491e-106     349     33     54GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
GO:0006897; P:endocytosis; ISS:AgBase.
17Q5RBK4    746   CLCN5_PONAB H(+)/Cl(-) exchange transporter 5...7612e-106     349     32     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
18P51795    746   CLCN5_HUMAN H(+)/Cl(-) exchange transporter 5...7612e-106     349     32     53GO:0045177; C:apical part of cell; IDA:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007588; P:excretion; TAS:ProtInc.
19Q5RDJ7    801   CLCN3_PONAB H(+)/Cl(-) exchange transporter 3...7453e-102     339     32     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0005247; F:voltage-gated chloride channel activity; ISS:UniProtKB.
20O94287    667   YOO2_SCHPO Uncharacterized chloride channel p...6431e-54     204     29     49GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
21O70496    803   CLCN7_MOUSE H(+)/Cl(-) exchange transporter 7...6512e-49     189     27     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
22P51799    803   CLCN7_RAT H(+)/Cl(-) exchange transporter 7 O...6512e-49     189     27     48GO:0031410; C:cytoplasmic vesicle; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
GO:0009268; P:response to pH; IDA:RGD.
23Q4PKH3    809   CLCN7_BOVIN H(+)/Cl(-) exchange transporter 7...6351e-45     178     27     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
24P51798    805   CLCN7_HUMAN H(+)/Cl(-) exchange transporter 7...6512e-44     175     27     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
25P35523    988   CLCN1_HUMAN Chloride channel protein 1 OS=Hom...5917e-40     162     26     44GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005247; F:voltage-gated chloride channel activity; TAS:ProtInc.
GO:0006936; P:muscle contraction; TAS:ProtInc.
26P92943    792   CLCD_ARATH Chloride channel protein CLC-d OS=...6581e-39     160     26     45GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
GO:0009826; P:unidimensional cell growth; IMP:TAIR.
27Q64347    994   CLCN1_MOUSE Chloride channel protein 1 OS=Mus...5872e-39     160     26     45GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.::GO:0042383; C:sarcolemma; IDA:MGI.
GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
GO:0019227; P:neuronal action potential propagation; IMP:MGI.
28Q54C67    809   CLCF_DICDI Chloride channel protein F OS=Dict...4869e-39     158     28     48GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
29Q75JF3    757   CLCC_DICDI Chloride channel protein C OS=Dict...6651e-38     157     24     45GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
30P35524    994   CLCN1_RAT Chloride channel protein 1 OS=Rattu...5812e-38     157     26     45GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
GO:0005247; F:voltage-gated chloride channel activity; IDA:RGD.
31Q96282    779   CLCC_ARATH Chloride channel protein CLC-c OS=...6521e-37     154     25     44GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
records
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