Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR036C
Length:
892
Number of sequences:
5887
Description:
YJR036C HUL4 SGDID:S000003797, Chr X from 503391-500713, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40985    892   HUL4_YEAST Probable E3 ubiquitin-protein liga...8920     1844     100     100GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
2Q757T0    839   HUL4_ASHGO Probable E3 ubiquitin-protein liga...8520     655     43     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
3O94275    807   MUG30_SCHPO Probable E3 ubiquitin-protein lig...8431e-105     352     31     48GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
4Q5RD78    776   HECD2_PONAB Probable E3 ubiquitin-protein lig...5081e-76     271     34     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
5Q5U5R9    776   HECD2_HUMAN Probable E3 ubiquitin-protein lig...5082e-76     270     34     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
6Q8CDU6    774   HECD2_MOUSE Probable E3 ubiquitin-protein lig...5082e-75     268     35     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
7Q05086    875   UBE3A_HUMAN Ubiquitin-protein ligase E3A OS=H...4297e-70     253     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007420; P:brain development; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
8O08759    885   UBE3A_MOUSE Ubiquitin-protein ligase E3A OS=M...4242e-65     240     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
9Q5PQN1    1057   HERC4_RAT Probable E3 ubiquitin-protein ligas...4945e-63     234     31     52GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
10Q6PAV2    1057   HERC4_MOUSE Probable E3 ubiquitin-protein lig...4931e-62     233     31     51GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.
11Q5GLZ8    1057   HERC4_HUMAN Probable E3 ubiquitin-protein lig...4973e-57     217     31     52GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
12Q15034    1050   HERC3_HUMAN Probable E3 ubiquitin-protein lig...4627e-51     197     31     50GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
13Q9UII4    1024   HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS...4267e-51     197     30     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
14Q0CCL1    808   RSP5_ASPTN Probable E3 ubiquitin-protein liga...3751e-48     189     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
15Q5BDP1    821   RSP5_EMENI E3 ubiquitin-protein ligase RSP5 O...3752e-48     188     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
16Q92462    767   PUB1_SCHPO E3 ubiquitin-protein ligase pub1 O...3752e-48     187     34     53GO:0071944; C:cell periphery; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:PomBase.
GO:0060360; P:negative regulation of leucine import in response to ammonium ion; IMP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.::GO:0051453; P:regulation of intracellular pH; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.::GO:0034762; P:regulation of transmembrane transport; IMP:PomBase.
17O14326    786   PUB3_SCHPO E3 ubiquitin-protein ligase pub3 O...3746e-48     186     35     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
18Q4WTF3    813   RSP5_ASPFU Probable E3 ubiquitin-protein liga...3757e-48     186     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
19B0XQ72    813   RSP5_ASPFC Probable E3 ubiquitin-protein liga...3757e-48     186     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
20A1D3C5    816   RSP5_NEOFI Probable E3 ubiquitin-protein liga...3751e-47     186     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
21Q9P4Z1    4026   TOM1_NEUCR E3 ubiquitin-protein ligase TOM1-l...3801e-47     189     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
22A2QQ28    821   RSP5_ASPNC Probable E3 ubiquitin-protein liga...3751e-47     186     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
23B8N7E5    812   RSP5_ASPFN Probable E3 ubiquitin-protein liga...3753e-47     184     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
24Q8GY23    3681   UPL1_ARATH E3 ubiquitin-protein ligase UPL1 O...3791e-46     185     31     52GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
25A1CQG2    815   RSP5_ASPCL Probable E3 ubiquitin-protein liga...3751e-46     182     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
26O13834    3227   PTR1_SCHPO E3 ubiquitin-protein ligase ptr1 O...3802e-46     185     32     52GO:0005634; C:nucleus; IDA:PomBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
27Q9CUN6    731   SMUF1_MOUSE E3 ubiquitin-protein ligase SMURF...3802e-46     181     33     51GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; IMP:MGI.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
28A9JRZ0    765   SMUF2_DANRE E3 ubiquitin-protein ligase SMURF...3772e-46     182     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
29Q2UBP1    816   RSP5_ASPOR Probable E3 ubiquitin-protein liga...3762e-46     182     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
30Q9HCE7    757   SMUF1_HUMAN E3 ubiquitin-protein ligase SMURF...3805e-46     180     33     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0048185; F:activin binding; IPI:BHF-UCL.::GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0007398; P:ectoderm development; TAS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; TAS:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:BHF-UCL.::GO:0034394; P:protein localization at cell surface; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0032801; P:receptor catabolic process; IDA:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.
31Q8H0T4    3658   UPL2_ARATH E3 ubiquitin-protein ligase UPL2 O...3799e-46     183     30     52GO:0005829; C:cytosol; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
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