Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR031C
Length:
1408
Number of sequences:
5887
Description:
YJR031C GEA1 SGDID:S000003792, Chr X from 490812-486586, Genome Release 64-1-1, reverse complement, Verified ORF, "Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P47102    1408   GEA1_YEAST ARF guanine-nucleotide exchange fa...14080     2862     100     100GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000137; C:Golgi cis cisterna; IDA:SGD.::GO:0005798; C:Golgi-associated vesicle; IPI:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0030036; P:actin cytoskeleton organization; IGI:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IGI:SGD.
2P39993    1459   GEA2_YEAST ARF guanine-nucleotide exchange fa...14230     1390     51     69GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000137; C:Golgi cis cisterna; IDA:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0030036; P:actin cytoskeleton organization; IGI:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IGI:SGD.::GO:0033363; P:secretory granule organization; IMP:SGD.
3Q9P7R8    1462   YHV3_SCHPO Uncharacterized protein C211.03 OS...10592e-115     402     29     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005488; F:binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; ISS:PomBase.::GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
4Q42510    1451   EMB30_ARATH Pattern formation protein EMB30 O...10371e-50     200     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0010292; F:GTP:GDP antiporter activity; IGI:TAIR.::GO:0042803; F:protein homodimerization activity; IPI:TAIR.
GO:0010540; P:basipetal auxin transport; IMP:TAIR.::GO:0007155; P:cell adhesion; IMP:TAIR.::GO:0007047; P:cellular cell wall organization; IMP:TAIR.::GO:0000911; P:cytokinesis by cell plate formation; IMP:TAIR.::GO:0010386; P:lateral root primordium development; IMP:TAIR.::GO:0009942; P:longitudinal axis specification; IMP:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0048209; P:regulation of vesicle targeting, to, from or within Golgi; TAS:TAIR.::GO:0009826; P:unidimensional cell growth; IMP:TAIR.
5Q9R1D7    1856   GBF1_CRIGR Golgi-specific brefeldin A-resista...2320.000000007     64.7     25     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
6Q92538    1859   GBF1_HUMAN Golgi-specific brefeldin A-resista...2310.00000002     62.8     24     51GO:0000139; C:Golgi membrane; TAS:Reactome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
7P11075    2009   SEC7_YEAST Protein transport protein SEC7 OS=...2171e-29     132     36     53GO:0005829; C:cytosol; IDA:SGD.::GO:0005798; C:Golgi-associated vesicle; IDA:SGD.::GO:0005770; C:late endosome; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0005488; F:binding; IEA:InterPro.
GO:0000045; P:autophagic vacuole assembly; IMP:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
8Q9P7V5    1822   SEC7B_SCHPO Protein transport protein sec72 O...2797e-29     130     32     51GO:0005938; C:cell cortex; IDA:PomBase.::GO:0000137; C:Golgi cis cisterna; IDA:PomBase.::GO:0000138; C:Golgi trans cisterna; IDA:PomBase.::GO:0005798; C:Golgi-associated vesicle; ISS:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005488; F:binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; ISS:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
9Q80YW0    393   CYH4_MOUSE Cytohesin-4 OS=Mus musculus (Mouse...2191e-27     121     35     52GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
10Q9UT02    1811   SEC7A_SCHPO Protein transport protein sec71 O...2182e-27     125     34     53GO:0005798; C:Golgi-associated vesicle; ISS:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005488; F:binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; ISS:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
11P97694    398   CYH1_RAT Cytohesin-1 OS=Rattus norvegicus (Ra...2634e-27     120     34     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
12Q9QX11    398   CYH1_MOUSE Cytohesin-1 OS=Mus musculus (Mouse...2634e-27     120     34     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005923; C:tight junction; IDA:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
13Q9Y6D6    1849   BIG1_HUMAN Brefeldin A-inhibited guanine nucl...1331.4     37.4     23     50GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0017022; F:myosin binding; IPI:UniProtKB.
GO:0006887; P:exocytosis; TAS:ProtInc.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
14Q8R0S2    961   IQEC1_MOUSE IQ motif and SEC7 domain-containi...2191e-26     122     33     54GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
15Q9UIA0    394   CYH4_HUMAN Cytohesin-4 OS=Homo sapiens (Human...2201e-26     118     35     51GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
16Q6DN90    963   IQEC1_HUMAN IQ motif and SEC7 domain-containi...2191e-26     122     32     54GO:0030054; C:cell junction; IDA:HPA.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
17O46382    1849   BIG1_BOVIN Brefeldin A-inhibited guanine nucl...1333.6     35.8     23     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
18Q9Y6D5    1785   BIG2_HUMAN Brefeldin A-inhibited guanine nucl...1333.6     35.8     23     49GO:0005829; C:cytosol; IDA:MGI.::GO:0000139; C:Golgi membrane; IDA:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0006887; P:exocytosis; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
19Q15438    398   CYH1_HUMAN Cytohesin-1 OS=Homo sapiens (Human...2636e-26     116     35     50GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IDA:MGI.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
20Q76MZ1    398   CYH1_CHLAE Cytohesin-1 OS=Chlorocebus aethiop...2636e-26     116     35     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
21Q76M68    1194   IQEC3_RAT IQ motif and SEC7 domain-containing...2194e-25     117     33     53GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032857; P:activation of ARF GTPase activity; IDA:UniProtKB.
22Q3TES0    1195   IQEC3_MOUSE IQ motif and SEC7 domain-containi...2194e-25     117     33     53GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0060077; C:inhibitory synapse; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
23Q54KA7    986   SECG_DICDI Ankyrin repeat, PH and SEC7 domain...2205e-25     117     32     53GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
24Q9UPP2    1182   IQEC3_HUMAN IQ motif and SEC7 domain-containi...2197e-25     116     33     53GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
25Q5DU25    1478   IQEC2_MOUSE IQ motif and SEC7 domain-containi...2263e-24     114     32     55GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
26Q2KI41    410   CYH2_BOVIN Cytohesin-2 OS=Bos taurus (Bovine)...2603e-24     111     31     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; ISS:RefGenome.
27Q5JU85    1478   IQEC2_HUMAN IQ motif and SEC7 domain-containi...2263e-24     114     32     55GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
28O08967    399   CYH3_MOUSE Cytohesin-3 OS=Mus musculus (Mouse...2514e-24     110     34     49GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IPI:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0045785; P:positive regulation of cell adhesion; IDA:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
29P97696    400   CYH3_RAT Cytohesin-3 OS=Rattus norvegicus (Ra...2514e-24     110     34     49GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
30O43739    400   CYH3_HUMAN Cytohesin-3 OS=Homo sapiens (Human...2514e-24     110     34     49GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; TAS:ProtInc.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; TAS:ProtInc.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
31Q76MY7    399   CYH2_CHLAE Cytohesin-2 OS=Chlorocebus aethiop...2605e-24     110     31     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
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