Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJR010C-A
Length:
94
Number of sequences:
5887
Description:
YJR010C-A SPC1 SGDID:S000003770, Chr X from 458361-458077, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER), homolog of the SPC12 subunit of mammalian signal peptidase complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P46965    94   SPC1_YEAST Signal peptidase complex subunit S...944e-63     192     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005787; C:signal peptidase complex; IDA:SGD.
GO:0008233; F:peptidase activity; IEA:InterPro.
GO:0045047; P:protein targeting to ER; IGI:SGD.::GO:0006465; P:signal peptide processing; IPI:SGD.
2Q74Z81    91   SPC1_ASHGO Microsomal signal peptidase subuni...891e-16     73.2     44     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
3Q944J0    92   SPCS1_ARATH Probable signal peptidase complex...690.000002     45.4     29     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
4Q54Y83    80   SPCS1_DICDI Signal peptidase complex subunit ...720.00004     42     25     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
5O44953    105   SPCS1_CAEEL Probable signal peptidase complex...770.0004     39.3     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006465; P:signal peptide processing; IEA:InterPro.
6Q9VAL0    98   SPCS1_DROME Signal peptidase complex subunit ...690.001     38.1     23     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
7G2TRR4    78   SPC1_SCHPO Microsomal signal peptidase subuni...710.002     37     31     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
8Q5RF96    102   SPCS1_PONAB Signal peptidase complex subunit ...700.008     35.8     24     53GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
9B0FWK4    102   SPCS1_PIG Signal peptidase complex subunit 1 ...700.008     35.8     24     53GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
10Q3T134    102   SPCS1_BOVIN Signal peptidase complex subunit ...700.009     35.4     27     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
11Q9D958    161   SPCS1_MOUSE Signal peptidase complex subunit ...700.051     34.7     24     53GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; IEA:InterPro.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.::GO:0043022; F:ribosome binding; IDA:MGI.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006465; P:signal peptide processing; IEA:InterPro.
12Q9Y6A9    169   SPCS1_HUMAN Signal peptidase complex subunit ...700.066     34.3     24     53GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005787; C:signal peptidase complex; TAS:UniProtKB.
GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0006465; P:signal peptide processing; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.::GO:0006412; P:translation; TAS:Reactome.
13A1K7T4    638   KUP_AZOSB Probable potassium transport system...340.82     31.6     41     74GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
14Q60934    836   GRIK1_MOUSE Glutamate receptor, ionotropic ka...271.5     30.8     44     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro.
GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; TAS:UniProtKB.
15Q38PU3    908   GRIK2_MACFA Glutamate receptor, ionotropic ka...271.6     30.8     44     59GO:0030424; C:axon; IDA:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro.
16P22756    949   GRIK1_RAT Glutamate receptor, ionotropic kain...271.6     30.4     44     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0043195; C:terminal button; IDA:RGD.
GO:0008144; F:drug binding; IDA:RGD.::GO:0005234; F:extracellular-glutamate-gated ion channel activity; IDA:RGD.::GO:0016595; F:glutamate binding; IDA:RGD.::GO:0015277; F:kainate selective glutamate receptor activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0022843; F:voltage-gated cation channel activity; IMP:RGD.
GO:0032229; P:negative regulation of synaptic transmission, GABAergic; IDA:RGD.::GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IDA:RGD.::GO:0007399; P:nervous system development; IMP:RGD.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IDA:RGD.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:RGD.
17Q16478    980   GRIK5_HUMAN Glutamate receptor, ionotropic ka...381.7     30.4     39     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0015277; F:kainate selective glutamate receptor activity; IDA:UniProtKB.
GO:0007268; P:synaptic transmission; NAS:UniProtKB.
18Q38PU4    918   GRIK1_MACFA Glutamate receptor, ionotropic ka...271.7     30.4     44     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro.
19P39086    918   GRIK1_HUMAN Glutamate receptor, ionotropic ka...271.7     30.4     44     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0015277; F:kainate selective glutamate receptor activity; IDA:UniProtKB.
GO:0007417; P:central nervous system development; TAS:ProtInc.
20Q63273    979   GRIK5_RAT Glutamate receptor, ionotropic kain...381.7     30.4     39     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0015277; F:kainate selective glutamate receptor activity; IDA:RGD.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IMP:UniProtKB.
GO:0071333; P:cellular response to glucose stimulus; IEP:RGD.::GO:0051649; P:establishment of localization in cell; IMP:UniProtKB.::GO:0043526; P:neuroprotection; IMP:RGD.::GO:0006621; P:protein retention in ER lumen; IMP:UniProtKB.::GO:0043113; P:receptor clustering; IDA:UniProtKB.
21Q61626    979   GRIK5_MOUSE Glutamate receptor, ionotropic ka...381.7     30.4     39     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
22Q8Y8Q5    880   LMCA1_LISMO Calcium-transporting ATPase lmo08...352.4     30     46     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005388; F:calcium-transporting ATPase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
23Q16099    956   GRIK4_HUMAN Glutamate receptor, ionotropic ka...452.7     30     36     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0015277; F:kainate selective glutamate receptor activity; TAS:ProtInc.
GO:0007268; P:synaptic transmission; TAS:Reactome.
24Q5P3E3    640   KUP_AROAE Probable potassium transport system...342.9     30     38     71GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
25Q01812    956   GRIK4_RAT Glutamate receptor, ionotropic kain...452.9     30     36     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0043195; C:terminal button; IDA:RGD.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0015277; F:kainate selective glutamate receptor activity; TAS:RGD.
GO:0031960; P:response to corticosteroid stimulus; IEP:RGD.::GO:0007268; P:synaptic transmission; TAS:RGD.
26Q5IS46    956   GRIK4_PANTR Glutamate receptor, ionotropic ka...452.9     30     36     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro.
27Q8BMF5    956   GRIK4_MOUSE Glutamate receptor, ionotropic ka...452.9     30     36     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0032983; C:kainate selective glutamate receptor complex; IPI:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0045211; C:postsynaptic membrane; IDA:MGI.::GO:0042734; C:presynaptic membrane; IDA:MGI.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
28P39087    908   GRIK2_MOUSE Glutamate receptor, ionotropic ka...273.7     29.6     41     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IDA:GOC.::GO:0032983; C:kainate selective glutamate receptor complex; IPI:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IDA:MGI.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0015277; F:kainate selective glutamate receptor activity; IDA:MGI.
GO:0001662; P:behavioral fear response; IMP:MGI.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0006886; P:intracellular protein transport; IDA:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.::GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IGI:MGI.::GO:0019228; P:regulation of action potential in neuron; IMP:MGI.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI.::GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IMP:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.::GO:0042391; P:regulation of membrane potential; IDA:MGI.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.
29Q13002    908   GRIK2_HUMAN Glutamate receptor, ionotropic ka...273.7     29.6     41     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0015277; F:kainate selective glutamate receptor activity; IDA:UniProtKB.
GO:0031557; P:induction of programmed cell death in response to chemical stimulus; NAS:UniProtKB.::GO:0051402; P:neuron apoptotic process; IDA:UniProtKB.::GO:0050806; P:positive regulation of synaptic transmission; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:UniProtKB.
30P42260    908   GRIK2_RAT Glutamate receptor, ionotropic kain...273.7     29.6     41     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0043195; C:terminal button; IDA:RGD.
GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.::GO:0015277; F:kainate selective glutamate receptor activity; IDA:RGD.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD.
GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IDA:UniProtKB.::GO:0051402; P:neuron apoptotic process; IMP:UniProtKB.::GO:0043113; P:receptor clustering; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; IMP:UniProtKB.
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