rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P32525 | 599 | ECM25_YEAST Protein ECM25 OS=Saccharomyces ce... | 599 | 0 | 1213 | 100 | 100 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030447; P:filamentous growth; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 2 | Q07960 | 439 | RHG01_HUMAN Rho GTPase-activating protein 1 O... | 373 | 0.0003 | 47 | 21 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 3 | Q5FWK3 | 439 | RHG01_MOUSE Rho GTPase-activating protein 1 O... | 374 | 0.0006 | 46.2 | 21 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI. | | | | | | | | | | GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 4 | Q8BN58 | 729 | RHG28_MOUSE Rho GTPase-activating protein 28 ... | 144 | 0.0008 | 46.2 | 25 | 44 | | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 5 | Q9P2N2 | 729 | RHG28_HUMAN Rho GTPase-activating protein 28 ... | 145 | 0.005 | 43.5 | 25 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 6 | Q5TG30 | 622 | RHG40_HUMAN Rho GTPase-activating protein 40 ... | 143 | 0.019 | 41.6 | 24 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 7 | P13608 | 2364 | PGCA_BOVIN Aggrecan core protein OS=Bos tauru... | 157 | 0.03 | 41.2 | 29 | 43 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005540; F:hyaluronic acid binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:InterPro. | 8 | Q767L8 | 2042 | MDC1_PIG Mediator of DNA damage checkpoint pr... | 171 | 7.6 | 33.5 | 25 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 9 | O54940 | 326 | BNIP2_MOUSE BCL2/adenovirus E1B 19 kDa protei... | 189 | 0.036 | 40.4 | 22 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005635; C:nuclear envelope; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.::GO:0051057; P:positive regulation of small GTPase mediated signal transduction; IMP:MGI. | 10 | Q9VTU3 | 476 | RG68F_DROME Rho GTPase-activating protein 68F... | 297 | 0.064 | 39.7 | 19 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:FlyBase. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007370; P:ventral furrow formation; IMP:FlyBase. | 11 | Q12982 | 314 | BNIP2_HUMAN BCL2/adenovirus E1B 19 kDa protei... | 133 | 0.068 | 39.3 | 25 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005635; C:nuclear envelope; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:UniProtKB.::GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IPI:MGI.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome. | 12 | Q80T03 | 2850 | MUC6_MOUSE Mucin-6 OS=Mus musculus (Mouse). G... | 132 | 0.078 | 40 | 26 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 13 | Q0IHU9 | 316 | PRUN2_XENTR Protein prune homolog 2 OS=Xenopu... | 156 | 0.18 | 38.1 | 25 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 14 | Q86L99 | 1523 | GACHH_DICDI Rho GTPase-activating protein gac... | 166 | 0.58 | 37 | 22 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 15 | Q8WUY3 | 3088 | PRUN2_HUMAN Protein prune homolog 2 OS=Homo s... | 155 | 1.4 | 35.8 | 25 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016462; F:pyrophosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051318; P:G1 phase; IEP:HGNC.::GO:0006917; P:induction of apoptosis; IMP:HGNC. | 16 | Q52KR3 | 3084 | PRUN2_MOUSE Protein prune homolog 2 OS=Mus mu... | 151 | 2.2 | 35 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016462; F:pyrophosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 17 | Q5R4Q8 | 323 | PRUN2_PONAB Protein prune homolog 2 OS=Pongo ... | 154 | 2.2 | 34.7 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 18 | Q5BJR4 | 322 | PRUN2_RAT Protein prune homolog 2 OS=Rattus n... | 150 | 2.5 | 34.3 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 19 | Q6ZRS2 | 3230 | SRCAP_HUMAN Helicase SRCAP OS=Homo sapiens (H... | 149 | 9.3 | 33.1 | 21 | 42 | GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0043234; C:protein complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0004402; F:histone acetyltransferase activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q9Y493 | 2812 | ZAN_HUMAN Zonadhesin OS=Homo sapiens (Human).... | 119 | 3 | 34.7 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; NAS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007339; P:binding of sperm to zona pellucida; NAS:UniProtKB.::GO:0016337; P:cell-cell adhesion; NAS:UniProtKB. | 21 | Q9P227 | 1491 | RHG23_HUMAN Rho GTPase-activating protein 23 ... | 154 | 3.3 | 34.7 | 21 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 22 | Q69ZH9 | 1483 | RHG23_MOUSE Rho GTPase-activating protein 23 ... | 163 | 4.4 | 34.3 | 21 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 23 | G3MWR8 | 1960 | MICA3_BOVIN Protein-methionine sulfoxide oxid... | 90 | 4.5 | 34.3 | 31 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0071949; F:FAD binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW. | 24 | Q8K0Q5 | 663 | RHG18_MOUSE Rho GTPase-activating protein 18 ... | 179 | 5 | 33.9 | 20 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 25 | P16356 | 1856 | RPB1_CAEEL DNA-directed RNA polymerase II sub... | 97 | 5.3 | 33.9 | 36 | 48 | GO:0005665; C:DNA-directed RNA polymerase II, core complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001055; F:RNA polymerase II activity; IMP:WormBase. | | | | | | | | | | GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010458; P:exit from mitosis; IMP:WormBase.::GO:0007369; P:gastrulation; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006479; P:protein methylation; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 26 | P14248 | 2452 | RPB1_PLAFD DNA-directed RNA polymerase II sub... | 118 | 6 | 33.9 | 29 | 47 | GO:0005665; C:DNA-directed RNA polymerase II, core complex; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006366; P:transcription from RNA polymerase II promoter; IEA:InterPro. | 27 | Q7SBU6 | 2189 | EAF1_NEUCR Chromatin modification-related pro... | 119 | 6 | 33.9 | 29 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q66HB5 | 876 | RS10B_RAT Radial spoke head 10 homolog B OS=R... | 37 | 6.6 | 33.5 | 51 | 62 | | | | | | | | | | | | | | | | | | | | | | 29 | Q99102 | 2169 | MUC4_HUMAN Mucin-4 OS=Homo sapiens (Human). G... | 135 | 8.4 | 33.1 | 24 | 40 | GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005578; C:proteinaceous extracellular matrix; NAS:UniProtKB. | | | | | | | | | | GO:0005176; F:ErbB-2 class receptor binding; TAS:ProtInc.::GO:0030197; F:extracellular matrix constituent, lubricant activity; NAS:UniProtKB. | | | | | | | | | | GO:0007160; P:cell-matrix adhesion; IEA:InterPro.::GO:0016266; P:O-glycan processing; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome. | 30 | A2ASS6 | 35213 | TITIN_MOUSE Titin OS=Mus musculus (Mouse). GN... | 70 | 9.2 | 33.1 | 37 | 47 | GO:0031430; C:M band; IDA:MGI.::GO:0005859; C:muscle myosin complex; TAS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI. | | | | | | | | | | GO:0030506; F:ankyrin binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:MGI. | | | | | | | | | | GO:0007512; P:adult heart development; IMP:MGI.::GO:0055003; P:cardiac myofibril assembly; IMP:MGI.::GO:0043056; P:forward locomotion; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0006936; P:muscle contraction; IMP:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0045214; P:sarcomere organization; IMP:MGI.::GO:0001756; P:somitogenesis; IEP:BHF-UCL. | 31 | O42854 | 1611 | YFHH_SCHPO SH3 domain-containing protein C23A... | 110 | 9.8 | 33.1 | 30 | 45 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0017024; F:myosin I binding; ISS:PomBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase. |