Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL194W
Length:
513
Number of sequences:
5887
Description:
YJL194W CDC6 SGDID:S000003730, Chr X from 69338-70879, Genome Release 64-1-1, Verified ORF, "Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P09119    513   CDC6_YEAST Cell division control protein 6 OS...5130     1048     100     100GO:0031261; C:DNA replication preinitiation complex; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005656; C:pre-replicative complex; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0006267; P:pre-replicative complex assembly; IDA:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.
2O89033    562   CDC6_MOUSE Cell division control protein 6 ho...4981e-38     152     29     47GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
3Q99741    560   CDC6_HUMAN Cell division control protein 6 ho...4657e-36     144     28     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0051233; C:spindle midzone; IDA:BHF-UCL.::GO:0000922; C:spindle pole; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; TAS:Reactome.::GO:0000076; P:DNA replication checkpoint; TAS:ProtInc.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0008156; P:negative regulation of DNA replication; TAS:ProtInc.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IMP:BHF-UCL.::GO:0051984; P:positive regulation of chromosome segregation; IDA:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0090007; P:regulation of mitotic anaphase; IMP:BHF-UCL.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
4P41411    577   CDC18_SCHPO Cell division control protein 18 ...4492e-31     130     24     42GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0005656; C:pre-replicative complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003689; F:DNA clamp loader activity; ISS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0006267; P:pre-replicative complex assembly; ISS:PomBase.
5O16810    924   ORC1_DROME Origin recognition complex subunit...3007e-22     103     28     48GO:0005664; C:nuclear origin of replication recognition complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0006277; P:DNA amplification; IMP:FlyBase.::GO:0006270; P:DNA-dependent DNA replication initiation; IDA:FlyBase.
6P54789    707   ORC1_SCHPO Origin recognition complex subunit...5023e-21     101     24     43GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0000790; C:nuclear chromatin; IDA:PomBase.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:UniProtKB.::GO:0043596; C:nuclear replication fork; IC:PomBase.::GO:0005656; C:pre-replicative complex; IC:PomBase.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0003688; F:DNA replication origin binding; IDA:UniProtKB.
GO:0006270; P:DNA-dependent DNA replication initiation; IMP:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IMP:PomBase.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:PomBase.
7O74270    805   ORC1_CANAX Origin recognition complex subunit...5125e-18     90.9     24     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
8Q13415    861   ORC1_HUMAN Origin recognition complex subunit...4444e-16     85.1     22     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005664; C:nuclear origin of replication recognition complex; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0006270; P:DNA-dependent DNA replication initiation; TAS:ProtInc.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
9Q54RM2    631   ORC1_DICDI Origin recognition complex subunit...3000.000000000000001     83.6     26     44GO:0005634; C:nucleus; ISS:dictyBase.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; ISS:dictyBase.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006270; P:DNA-dependent DNA replication initiation; ISS:dictyBase.
10Q9JI69    850   ORC1_CRIGR Origin recognition complex subunit...4270.000000000000002     83.2     23     45GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
11Q6BSE2    810   ORC1_DEBHA Origin recognition complex subunit...2920.000000000000003     82.4     27     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
12Q8I615    1189   ORC1_PLAF7 Origin recognition complex subunit...2760.00000000000001     80.9     26     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
13Q9Z1N2    840   ORC1_MOUSE Origin recognition complex subunit...2930.00000000000008     77.8     23     44GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; TAS:MGI.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; TAS:MGI.
14Q80Z32    848   ORC1_RAT Origin recognition complex subunit 1...2990.00000000000008     77.8     24     44GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
15Q58DC8    863   ORC1_BOVIN Origin recognition complex subunit...4710.0000000000006     75.1     22     43GO:0005664; C:nuclear origin of replication recognition complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
16Q4JAS8    397   CDC61_SULAC Cell division control protein 6 h...4150.000000000001     73.6     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
17O29995    409   CDC61_ARCFU Cell division control protein 6 h...2770.000000000004     71.6     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
18P54788    886   ORC1_KLULA Origin recognition complex subunit...3460.000000000005     72.4     23     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000808; C:origin recognition complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
19Q9HKG3    404   CDC6_THEAC Cell division control protein 6 ho...1940.00000000006     68.2     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
20P54784    914   ORC1_YEAST Origin recognition complex subunit...3420.00000000008     68.2     23     42GO:0031261; C:DNA replication preinitiation complex; IDA:SGD.::GO:0005664; C:nuclear origin of replication recognition complex; IMP:SGD.::GO:0005656; C:pre-replicative complex; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IMP:SGD.::GO:0003682; F:chromatin binding; IDA:SGD.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030466; P:chromatin silencing at silent mating-type cassette; IDA:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0006267; P:pre-replicative complex assembly; IDA:SGD.
21Q97AP1    404   CDC6_THEVO Cell division control protein 6 ho...2770.000000007     61.2     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
22Q9V2F2    419   CDC6_PYRAB Cell division control protein 6 ho...2980.00000001     60.8     24     40
GO:0005524; F:ATP binding; IEA:HAMAP.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:HAMAP.
23Q5JET2    415   CDC6_PYRKO Cell division control protein 6 ho...2910.00000001     60.8     22     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
24A2SPC3    425   CDC6_METLZ Cell division control protein 6 ho...3220.00000002     60.5     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
25B6YUE9    415   CDC6_THEON Cell division control protein 6 ho...3070.00000002     60.1     22     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
26Q2FN79    424   CDC6_METHJ Cell division control protein 6 ho...2800.00000003     59.7     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
27P81413    420   CDC6_PYRFU Cell division control protein 6 ho...3080.00000003     59.3     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
28O57864    419   CDC6_PYRHO Cell division control protein 6 ho...2990.0000002     56.6     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
29Q6KZL0    408   CDC6_PICTO Cell division control protein 6 ho...3320.0000008     55.1     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
30A3CRD6    427   CDC6_METMJ Cell division control protein 6 ho...3050.000001     54.3     24     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
31A7I464    430   CDC6_METB6 Cell division control protein 6 ho...2790.000002     53.9     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
records
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