Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL187C
Length:
819
Number of sequences:
5887
Description:
YJL187C SWE1 SGDID:S000003723, Chr X from 79262-76803, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32944    819   SWE1_YEAST Mitosis inhibitor protein kinase S...8190     1685     100     100GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.::GO:0004713; F:protein tyrosine kinase activity; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000078; P:cell shape checkpoint; IDA:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010697; P:negative regulation of spindle pole body separation; IMP:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:SGD.::GO:0040020; P:regulation of meiosis; IGI:SGD.
2P30290    581   MIK1_SCHPO Mitosis inhibitor protein kinase m...2944e-47     181     37     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; TAS:PomBase.
3Q91618    548   PMYT1_XENLA Membrane-associated tyrosine- and...2342e-32     136     34     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
4Q9ESG9    490   PMYT1_MOUSE Membrane-associated tyrosine- and...2353e-29     126     32     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
5Q99640    499   PMYT1_HUMAN Membrane-associated tyrosine- and...2344e-29     125     31     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; TAS:ProtInc.::GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0007088; P:regulation of mitosis; TAS:ProtInc.
6Q9NI63    533   PMYT1_DROME Membrane-associated tyrosine- and...3262e-28     124     28     48GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:UniProtKB.
GO:0007143; P:female meiosis; IMP:FlyBase.::GO:0048142; P:germarium-derived cystoblast division; IMP:FlyBase.::GO:0007140; P:male meiosis; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0045930; P:negative regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0048137; P:spermatocyte division; IMP:FlyBase.::GO:0007284; P:spermatogonial cell division; IMP:FlyBase.
7Q54E34    352   Y6398_DICDI Probable protein kinase DDB_G0291...2451e-27     119     31     53GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.::GO:0004713; F:protein tyrosine kinase activity; ISS:dictyBase.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
8Q626B1    656   PMY13_CAEBR Membrane-associated tyrosine- and...2341e-26     120     31     55GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0051327; P:M phase of meiotic cell cycle; ISS:UniProtKB.::GO:0051447; P:negative regulation of meiotic cell cycle; ISS:UniProtKB.::GO:0002119; P:nematode larval development; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
9Q54F40    778   Y1133_DICDI Probable protein kinase DDB_G0291...2724e-26     118     31     49GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.::GO:0004713; F:protein tyrosine kinase activity; ISS:dictyBase.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
10Q9LT35    416   NEK6_ARATH Serine/threonine-protein kinase Ne...2105e-26     115     30     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
11O18209    677   PMY13_CAEEL Membrane-associated tyrosine- and...2488e-25     114     31     54GO:0019898; C:extrinsic to membrane; TAS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0051327; P:M phase of meiotic cell cycle; IMP:UniProtKB.::GO:0051447; P:negative regulation of meiotic cell cycle; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:UniProtKB.::GO:0001556; P:oocyte maturation; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
12P0C1S8    567   WEE2_HUMAN Wee1-like protein kinase 2 OS=Homo...2762e-24     112     30     46GO:0005813; C:centrosome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
GO:0007343; P:egg activation; ISS:UniProtKB.::GO:0007143; P:female meiosis; ISS:UniProtKB.::GO:0035038; P:female pronucleus assembly; ISS:UniProtKB.::GO:0007137; P:meiotic metaphase II; ISS:UniProtKB.::GO:0007128; P:meiotic prophase I; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:InterPro.::GO:0060283; P:negative regulation of oocyte development; ISS:UniProtKB.::GO:0060631; P:regulation of meiosis I; ISS:UniProtKB.
13Q6YY75    534   NEK6_ORYSJ Serine/threonine-protein kinase Ne...2123e-23     108     31     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
14Q66JT0    555   WEE2_MOUSE Wee1-like protein kinase 2 OS=Mus ...2865e-23     107     28     46GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
GO:0007343; P:egg activation; IMP:UniProtKB.::GO:0007143; P:female meiosis; IMP:UniProtKB.::GO:0035038; P:female pronucleus assembly; IMP:UniProtKB.::GO:0007137; P:meiotic metaphase II; IMP:UniProtKB.::GO:0007128; P:meiotic prophase I; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:InterPro.::GO:0060283; P:negative regulation of oocyte development; IMP:UniProtKB.::GO:0060631; P:regulation of meiosis I; IMP:UniProtKB.
15D2HHP1    565   WEE2_AILME Wee1-like protein kinase 2 OS=Ailu...2761e-22     106     30     46GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
GO:0007343; P:egg activation; ISS:UniProtKB.::GO:0007143; P:female meiosis; ISS:UniProtKB.::GO:0035038; P:female pronucleus assembly; ISS:UniProtKB.::GO:0007137; P:meiotic metaphase II; ISS:UniProtKB.::GO:0007128; P:meiotic prophase I; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:InterPro.::GO:0060283; P:negative regulation of oocyte development; ISS:UniProtKB.::GO:0060631; P:regulation of meiosis I; ISS:UniProtKB.
16Q8RXT4    555   NEK4_ARATH Serine/threonine-protein kinase Ne...2141e-22     106     29     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
17Q1LX51    532   WEE2_DANRE Wee1-like protein kinase 2 OS=Dani...2872e-22     105     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:InterPro.
18E2RSS3    567   WEE2_CANFA Wee1-like protein kinase 2 OS=Cani...2903e-22     105     29     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
GO:0007343; P:egg activation; ISS:UniProtKB.::GO:0007143; P:female meiosis; ISS:UniProtKB.::GO:0035038; P:female pronucleus assembly; ISS:UniProtKB.::GO:0007137; P:meiotic metaphase II; ISS:UniProtKB.::GO:0007128; P:meiotic prophase I; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:InterPro.::GO:0060283; P:negative regulation of oocyte development; ISS:UniProtKB.::GO:0060631; P:regulation of meiosis I; ISS:UniProtKB.
19E1BK52    966   STK10_BOVIN Serine/threonine-protein kinase 1...2073e-22     106     32     52GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
20Q7SY52    974   STK10_DANRE Serine/threonine-protein kinase 1...2103e-22     106     30     51GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
21O55098    966   STK10_MOUSE Serine/threonine-protein kinase 1...2075e-22     105     31     51GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
22A4PES0    565   WEE2_PIG Wee1-like protein kinase 2 OS=Sus sc...2758e-22     103     28     46GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
GO:0007143; P:female meiosis; IDA:UniProtKB.::GO:0007128; P:meiotic prophase I; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:InterPro.::GO:0060283; P:negative regulation of oocyte development; IDA:UniProtKB.::GO:0060631; P:regulation of meiosis I; IDA:UniProtKB.
23E9PTG8    967   STK10_RAT Serine/threonine-protein kinase 10 ...2049e-22     105     31     51GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
24Q6ZEZ5    585   NEK3_ORYSJ Serine/threonine-protein kinase Ne...2111e-21     103     29     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
25O94804    968   STK10_HUMAN Serine/threonine-protein kinase 1...2072e-21     104     32     51GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; TAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
26Q10GB1    599   NEK1_ORYSJ Serine/threonine-protein kinase Ne...2112e-21     102     29     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
27Q0WPH8    956   NEK5_ARATH Serine/threonine-protein kinase Ne...2134e-21     102     28     52GO:0055028; C:cortical microtubule; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009913; P:epidermal cell differentiation; IMP:TAIR.::GO:0007017; P:microtubule-based process; IMP:TAIR.
28Q2QMH1    591   NEK2_ORYSJ Serine/threonine-protein kinase Ne...2115e-21     101     29     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
29A2ZMH2    591   NEK2_ORYSI Serine/threonine-protein kinase Ne...2115e-21     101     29     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
30Q9SLI2    612   NEK1_ARATH Serine/threonine-protein kinase Ne...2127e-21     101     29     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
31Q94CU5    943   NEK5_ORYSJ Serine/threonine-protein kinase Ne...2107e-21     102     28     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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