rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q2LYK3 | 777 | PLK4_DROPS Serine/threonine-protein kinase PL... | 205 | 0.000000000000003 | 84 | 25 | 53 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 182 | O04534 | 666 | LRK51_ARATH Putative L-type lectin-domain con... | 222 | 0.000000000000003 | 83.6 | 26 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 183 | P22612 | 351 | KAPCG_HUMAN cAMP-dependent protein kinase cat... | 276 | 0.000000000000003 | 81.6 | 26 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0008584; P:male gonad development; TAS:ProtInc.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 184 | Q9JI10 | 497 | STK3_MOUSE Serine/threonine-protein kinase 3 ... | 228 | 0.000000000000003 | 82.8 | 27 | 49 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0060215; P:primitive hemopoiesis; IGI:MGI. | 185 | B4HBU3 | 777 | PLK4_DROPE Serine/threonine-protein kinase PL... | 205 | 0.000000000000003 | 83.6 | 25 | 53 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 186 | Q6C3J2 | 371 | IPL1_YARLI Spindle assembly checkpoint kinase... | 287 | 0.000000000000003 | 81.6 | 25 | 45 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 187 | Q6P3Q4 | 485 | STK4_XENTR Serine/threonine-protein kinase 4 ... | 231 | 0.000000000000003 | 82.8 | 27 | 49 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 188 | P51817 | 358 | PRKX_HUMAN cAMP-dependent protein kinase cata... | 314 | 0.000000000000004 | 81.3 | 24 | 42 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.::GO:0043542; P:endothelial cell migration; IMP:UniProtKB.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060562; P:epithelial tube morphogenesis; IDA:UniProtKB.::GO:0060993; P:kidney morphogenesis; IDA:UniProtKB.::GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:2000696; P:regulation of epithelial cell differentiation involved in kidney development; IDA:UniProtKB. | 189 | P06244 | 397 | KAPA_YEAST cAMP-dependent protein kinase type... | 227 | 0.000000000000004 | 82 | 25 | 50 | GO:0005952; C:cAMP-dependent protein kinase complex; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IMP:SGD. | 190 | P34099 | 648 | KAPC_DICDI cAMP-dependent protein kinase cata... | 230 | 0.000000000000004 | 83.2 | 27 | 48 | GO:0005813; C:centrosome; TAS:dictyBase.::GO:0005829; C:cytosol; TAS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004691; F:cAMP-dependent protein kinase activity; TAS:dictyBase. | | | | | | | | | | GO:0031285; P:regulation of sorocarp stalk cell differentiation; IGI:dictyBase.::GO:0042173; P:regulation of sporulation resulting in formation of a cellular spore; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 191 | B0LT89 | 431 | STK24_RAT Serine/threonine-protein kinase 24 ... | 233 | 0.000000000000004 | 82.4 | 30 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0048680; P:positive regulation of axon regeneration; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 192 | Q13188 | 491 | STK3_HUMAN Serine/threonine-protein kinase 3 ... | 228 | 0.000000000000004 | 82.8 | 27 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB. | 193 | P49673 | 337 | KAPC_ASCSU cAMP-dependent protein kinase cata... | 270 | 0.000000000000004 | 80.9 | 25 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 194 | Q9FHG4 | 681 | LRKS7_ARATH Probable L-type lectin-domain con... | 214 | 0.000000000000004 | 83.2 | 29 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 195 | O22834 | 664 | LRK53_ARATH Probable L-type lectin-domain con... | 207 | 0.000000000000004 | 83.2 | 26 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 196 | Q8BGW6 | 398 | ST32A_MOUSE Serine/threonine-protein kinase 3... | 212 | 0.000000000000004 | 81.6 | 26 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 197 | P08458 | 490 | SPS1_YEAST Sporulation-specific protein 1 OS=... | 202 | 0.000000000000004 | 82.4 | 30 | 51 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005628; C:prospore membrane; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 198 | O97143 | 769 | PLK4_DROME Serine/threonine-protein kinase PL... | 205 | 0.000000000000005 | 83.2 | 27 | 52 | GO:0005814; C:centriole; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase. | 199 | Q6ZWH5 | 1172 | NEK10_HUMAN Serine/threonine-protein kinase N... | 208 | 0.000000000000005 | 83.2 | 28 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 200 | Q0CLX3 | 964 | ATG1_ASPTN Serine/threonine-protein kinase at... | 255 | 0.000000000000005 | 83.2 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 201 | Q99KH8 | 431 | STK24_MOUSE Serine/threonine-protein kinase 2... | 233 | 0.000000000000005 | 81.6 | 30 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 202 | Q90891 | 398 | MP2K2_CHICK Dual specificity mitogen-activate... | 208 | 0.000000000000005 | 81.3 | 26 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0070371; P:ERK1 and ERK2 cascade; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome. | 203 | Q9JM01 | 593 | CDKL3_RAT Cyclin-dependent kinase-like 3 OS=R... | 236 | 0.000000000000005 | 82.4 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 204 | A4IGM9 | 360 | AURKB_XENTR Aurora kinase B OS=Xenopus tropic... | 202 | 0.000000000000005 | 80.9 | 28 | 50 | GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0032133; C:chromosome passenger complex; ISS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 205 | Q55CE0 | 677 | MKCF_DICDI Probable serine/threonine-protein ... | 219 | 0.000000000000006 | 82.8 | 26 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 206 | Q6NW76 | 320 | AURKB_DANRE Aurora kinase B OS=Danio rerio (Z... | 249 | 0.000000000000006 | 80.1 | 24 | 48 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007059; P:chromosome segregation; IMP:ZFIN.::GO:0000910; P:cytokinesis; IMP:ZFIN.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 207 | Q7PLI7 | 748 | DCLK_DROME Serine/threonine-protein kinase CG... | 215 | 0.000000000000007 | 82.4 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 208 | Q7RZD3 | 954 | STE20_NEUCR Serine/threonine-protein kinase s... | 208 | 0.000000000000007 | 82.8 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 209 | Q9P286 | 719 | PAK7_HUMAN Serine/threonine-protein kinase PA... | 206 | 0.000000000000007 | 82.4 | 28 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0016049; P:cell growth; TAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB. | 210 | Q6DE08 | 361 | AUKBA_XENLA Aurora kinase B-A OS=Xenopus laev... | 202 | 0.000000000000007 | 80.5 | 28 | 49 | | | | | | | | | | | | | | | | | | | | | | 211 | B4IT27 | 750 | DCLK_DROYA Serine/threonine-protein kinase GE... | 215 | 0.000000000000007 | 82.4 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. |