Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL168C
Length:
733
Number of sequences:
5887
Description:
YJL168C SET2 SGDID:S000003704, Chr X from 104428-102227, Genome Release 64-1-1, reverse complement, Verified ORF, "Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P46995    733   SET2_YEAST Histone-lysine N-methyltransferase...7330     1513     100     100GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IPI:SGD.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IMP:SGD.
GO:0030437; P:ascospore formation; IMP:SGD.::GO:0016575; P:histone deacetylation; IMP:SGD.::GO:0060195; P:negative regulation of antisense RNA transcription; IMP:SGD.::GO:0071441; P:negative regulation of histone H3-K14 acetylation; IMP:SGD.::GO:2000616; P:negative regulation of histone H3-K9 acetylation; IMP:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:SGD.::GO:0035066; P:positive regulation of histone acetylation; IGI:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0006354; P:transcription elongation, DNA-dependent; IDA:SGD.
2Q6FX50    716   SET2_CANGA Histone-lysine N-methyltransferase...6910     868     62     77GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q757Y8    684   SET2_ASHGO Histone-lysine N-methyltransferase...6910     784     58     74GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q6CXP5    702   SET2_KLULA Histone-lysine N-methyltransferase...6970     738     55     69GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q6BM04    731   SET2_DEBHA Histone-lysine N-methyltransferase...4551e-140     437     50     66GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q59XV0    844   SET2_CANAL Histone-lysine N-methyltransferase...1000.0000003     57.4     34     54GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q2H988    894   SET2_CHAGB Histone-lysine N-methyltransferase...4362e-127     407     46     64GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q7RZU4    954   SET2_NEUCR Histone-lysine N-methyltransferase...4402e-127     409     46     63GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q4IB50    1051   SET2_GIBZE Histone-lysine N-methyltransferase...7081e-123     401     34     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q4WTT2    966   SET2_ASPFU Histone-lysine N-methyltransferase...7201e-122     397     37     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11O14026    798   SET2_SCHPO Histone-lysine N-methyltransferase...4364e-118     380     44     62GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:PomBase.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:PomBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:PomBase.
12Q2UTN6    965   SET2_ASPOR Histone-lysine N-methyltransferase...4736e-116     379     43     59GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q5ASA5    980   SET2_EMENI Histone-lysine N-methyltransferase...4738e-116     379     43     59GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q1DU03    1003   SET2_COCIM Histone-lysine N-methyltransferase...4471e-114     375     45     60GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15Q6C5G5    768   SET2_YARLI Histone-lysine N-methyltransferase...2650.000000002     64.7     26     42GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16P0CO28    834   SET2_CRYNJ Histone-lysine N-methyltransferase...4402e-90     307     41     57GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17P0CO29    834   SET2_CRYNB Histone-lysine N-methyltransferase...4402e-90     307     41     57GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q4PBL3    972   SET2_USTMA Histone-lysine N-methyltransferase...713.4     34.7     28     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q9VYD1    2313   C1716_DROME Probable histone-lysine N-methylt...2363e-53     204     43     58GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IMP:FlyBase.::GO:0051219; F:phosphoprotein binding; IPI:FlyBase.
GO:0035076; P:ecdysone receptor-mediated signaling pathway; IGI:FlyBase.::GO:0002168; P:instar larval development; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
20Q9BYW2    2564   SETD2_HUMAN Histone-lysine N-methyltransferas...2274e-52     201     43     63GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q2LAE1    1759   ASHH2_ARATH Histone-lysine N-methyltransferas...2003e-45     179     43     62GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048653; P:anther development; IMP:TAIR.::GO:0016116; P:carotenoid metabolic process; IMP:TAIR.::GO:0009553; P:embryo sac development; IMP:TAIR.::GO:0010452; P:histone H3-K36 methylation; IDA:TAIR.::GO:0009910; P:negative regulation of flower development; IMP:TAIR.::GO:0048481; P:ovule development; IMP:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0031062; P:positive regulation of histone methylation; IDA:TAIR.::GO:0040029; P:regulation of gene expression, epigenetic; IMP:TAIR.::GO:0010363; P:regulation of plant-type hypersensitive response; IMP:TAIR.::GO:0010223; P:secondary shoot formation; IMP:TAIR.
22Q84WW6    492   ASHH1_ARATH Histone-lysine N-methyltransferas...2355e-44     169     39     56GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006281; P:DNA repair; IMP:TAIR.::GO:0010224; P:response to UV-B; IEP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
23Q96L73    2696   NSD1_HUMAN Histone-lysine N-methyltransferase...2161e-42     171     42     56GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24O88491    2588   NSD1_MOUSE Histone-lysine N-methyltransferase...2162e-42     171     42     56GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035097; C:histone methyltransferase complex; IC:UniProtKB.
GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IDA:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0046965; F:retinoid X receptor binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q8BVE8    1365   NSD2_MOUSE Probable histone-lysine N-methyltr...1877e-40     162     42     58GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003289; P:atrial septum primum morphogenesis; IMP:MGI.::GO:0003290; P:atrial septum secundum morphogenesis; IMP:MGI.::GO:0060348; P:bone development; IMP:MGI.::GO:0003149; P:membranous septum morphogenesis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26O96028    1365   NSD2_HUMAN Probable histone-lysine N-methyltr...2144e-39     159     39     56GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q6P2L6    1439   NSD3_MOUSE Histone-lysine N-methyltransferase...2332e-38     157     35     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q9BZ95    1437   NSD3_HUMAN Histone-lysine N-methyltransferase...2244e-38     157     37     56GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q99MY8    2958   ASH1L_MOUSE Histone-lysine N-methyltransferas...1994e-38     157     38     58GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q9NR48    2969   ASH1L_HUMAN Histone-lysine N-methyltransferas...1995e-38     156     38     57GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005923; C:tight junction; TAS:ProtInc.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006323; P:DNA packaging; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
31Q9VW15    2226   ASH1_DROME Histone-lysine N-methyltransferase...2168e-36     149     37     51GO:0005634; C:nucleus; IC:FlyBase.::GO:0035327; C:transcriptionally active chromatin; IMP:FlyBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:FlyBase.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); NAS:FlyBase.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); NAS:FlyBase.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0018991; P:oviposition; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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