Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL168C
Length:
733
Number of sequences:
5887
Description:
YJL168C SET2 SGDID:S000003704, Chr X from 104428-102227, Genome Release 64-1-1, reverse complement, Verified ORF, "Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q3UG20    1868   MLL5_MOUSE Histone-lysine N-methyltransferase...1320.000002     55.1     30     49GO:0070688; C:MLL5-L complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0042800; F:histone methyltransferase activity (H3-K4 specific); ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; ISS:BHF-UCL.::GO:0006306; P:DNA methylation; IMP:UniProtKB.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0042119; P:neutrophil activation; IMP:UniProtKB.::GO:0002446; P:neutrophil mediated immunity; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0048384; P:retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
152Q28Z18    1314   SETB1_DROPS Histone-lysine N-methyltransferas...860.067     40.4     27     45GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0051038; P:negative regulation of transcription during meiosis; ISS:UniProtKB.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
153Q32KD2    1262   SETB1_DROME Histone-lysine N-methyltransferas...630.21     38.9     33     51GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005700; C:polytene chromosome; IDA:FlyBase.
GO:0010385; F:double-stranded methylated DNA binding; IDA:FlyBase.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:FlyBase.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044026; P:DNA hypermethylation; IMP:FlyBase.::GO:0048132; P:female germ-line stem cell division; IDA:FlyBase.::GO:0002165; P:instar larval or pupal development; IMP:FlyBase.::GO:0045814; P:negative regulation of gene expression, epigenetic; IDA:FlyBase.::GO:0051038; P:negative regulation of transcription during meiosis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
154Q8IZD2    1858   MLL5_HUMAN Histone-lysine N-methyltransferase...1320.000003     54.7     30     48GO:0070688; C:MLL5-L complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; IDA:BHF-UCL.::GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0042119; P:neutrophil activation; ISS:UniProtKB.::GO:0002446; P:neutrophil mediated immunity; ISS:UniProtKB.::GO:0030854; P:positive regulation of granulocyte differentiation; IMP:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0048384; P:retinoic acid receptor signaling pathway; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
155Q6YI93    703   SETB2_XENLA Histone-lysine N-methyltransferas...460.075     40     35     54GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
156Q9SRV2    338   SUVR3_ARATH Histone-lysine N-methyltransferas...1660.00003     50.4     27     43GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
157Q22795    242   SET1_CAEEL Probable histone-lysine N-methyltr...1200.00009     48.5     28     49GO:0005634; C:nucleus; IDA:WormBase.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
158O22781    651   SUVH2_ARATH Histone-lysine N-methyltransferas...910.00009     49.7     31     52GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005720; C:nuclear heterochromatin; IDA:TAIR.
GO:0042393; F:histone binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0040029; P:regulation of gene expression, epigenetic; IMP:TAIR.
159A4IGY9    697   SETB2_XENTR Histone-lysine N-methyltransferas...460.067     40.4     35     54GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
160Q946J2    734   SUVR1_ARATH Histone-lysine N-methyltransferas...1490.0001     49.3     24     40GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
161Q3EC60    312   SUVHA_ARATH Putative histone-lysine N-methylt...750.0002     48.1     35     52GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042393; F:histone binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
162Q9NQR1    393   SETD8_HUMAN N-lysine methyltransferase SETD8 ...1120.0002     48.1     30     44GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; IDA:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
163Q2YDW7    349   SETD8_MOUSE N-lysine methyltransferase SETD8 ...1120.0002     48.1     30     44GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
164Q2YDJ8    352   SETD8_BOVIN N-lysine methyltransferase SETD8 ...1120.0002     47.8     30     45GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
165Q1E9C0    624   SET9_COCIM Histone-lysine N-methyltransferase...570.0004     47.8     44     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
166O23372    2335   ATXR3_ARATH Probable histone-lysine N-methylt...760.0006     47.4     36     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:TAIR.
GO:0048440; P:carpel development; IMP:TAIR.::GO:0048443; P:stamen development; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
167Q9FNC7    717   SUVR2_ARATH Histone-lysine N-methyltransferas...1680.0006     47     23     42GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
168Q5AZY3    641   SET9_EMENI Histone-lysine N-methyltransferase...1240.0008     46.6     27     41GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
169P0CY36    605   Y1806_PHANO SET domain-containing protein SNO...1420.001     45.4     29     43
170Q8C267    713   SETB2_MOUSE Histone-lysine N-methyltransferas...610.034     41.2     34     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
171Q4X1W8    622   SET9_ASPFU Histone-lysine N-methyltransferase...570.002     45.4     40     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
172Q2H8D5    734   SET9_CHAGB Histone-lysine N-methyltransferase...580.002     45.1     40     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
173Q5QD03    957   SUVH3_CHLRE Histone-lysine N-methyltransferas...940.02     42     31     46GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042393; F:histone binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
174Q96T68    719   SETB2_HUMAN Histone-lysine N-methyltransferas...540.036     41.2     35     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0007067; P:mitosis; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
175Q2TZH4    625   SET9_ASPOR Histone-lysine N-methyltransferase...570.003     44.7     39     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
176Q0C9E6    629   SET9_ASPTN Histone-lysine N-methyltransferase...570.006     43.5     39     47GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
177Q0U3A4    662   SET9_PHANO Histone-lysine N-methyltransferase...570.008     43.1     39     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
178Q9T0G7    650   SUVH9_ARATH Probable histone-lysine N-methylt...2180.03     41.2     23     38GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042393; F:histone binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009294; P:DNA mediated transformation; IMP:TAIR.
179Q7SBJ9    783   SET9_NEUCR Histone-lysine N-methyltransferase...570.032     41.2     37     51GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
180Q15149    4684   PLEC_HUMAN Plectin OS=Homo sapiens (Human). G...920.043     41.2     33     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0030056; C:hemidesmosome; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0042383; C:sarcolemma; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
181Q4I8C9    662   SET9_GIBZE Histone-lysine N-methyltransferase...570.067     40.4     39     47GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
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