Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL168C
Length:
733
Number of sequences:
5887
Description:
YJL168C SET2 SGDID:S000003704, Chr X from 104428-102227, Genome Release 64-1-1, reverse complement, Verified ORF, "Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q8CFT2    1985   SET1B_MOUSE Histone-lysine N-methyltransferas...1280.000000000008     72.8     32     51GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
122O15047    1707   SET1A_HUMAN Histone-lysine N-methyltransferas...1490.000000000009     72.8     30     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
123Q8S4P4    895   EZ3_MAIZE Histone-lysine N-methyltransferase ...1750.00000000001     72.4     30     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
124Q8S4P5    894   EZ2_MAIZE Histone-lysine N-methyltransferase ...1750.00000000001     72     30     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
125P45975    635   SUV39_DROME Histone-lysine N-methyltransferas...1310.00000000001     71.6     34     51GO:0000775; C:chromosome, centromeric region; TAS:FlyBase.::GO:0000792; C:heterochromatin; TAS:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005701; C:polytene chromosome chromocenter; IDA:FlyBase.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030702; P:chromatin silencing at centromere; IMP:FlyBase.::GO:0006348; P:chromatin silencing at telomere; IMP:FlyBase.::GO:0006306; P:DNA methylation; IMP:FlyBase.::GO:0048132; P:female germ-line stem cell division; IDA:FlyBase.::GO:0031507; P:heterochromatin assembly; IMP:FlyBase.::GO:0070868; P:heterochromatin organization involved in chromatin silencing; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
126Q8W595    492   SUVR4_ARATH Histone-lysine N-methyltransferas...2430.00000000002     70.9     26     42GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
127Q4I5R3    1252   SET1_GIBZE Histone-lysine N-methyltransferase...1770.00000000004     70.5     29     44GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
128O17514    773   MES2_CAEEL Histone-lysine N-methyltransferase...1750.00000000005     70.1     32     46GO:0000786; C:nucleosome; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0042078; P:germ-line stem cell division; IMP:WormBase.::GO:0070734; P:histone H3-K27 methylation; IMP:WormBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
129Q9M364    1018   ATX3_ARATH Histone-lysine N-methyltransferase...1520.00000000008     69.3     30     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
130Q6PDK2    5588   MLL2_MOUSE Histone-lysine N-methyltransferase...1470.0000000002     68.6     30     52
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; IMP:UniProtKB.::GO:0051568; P:histone H3-K4 methylation; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001555; P:oocyte growth; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
131O14686    5537   MLL2_HUMAN Histone-lysine N-methyltransferase...1470.0000000002     68.6     30     52GO:0035097; C:histone methyltransferase complex; IPI:MGI.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; ISS:UniProtKB.::GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0001555; P:oocyte growth; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
132Q9C5P1    693   SUVH7_ARATH Histone-lysine N-methyltransferas...1600.0000000003     67     30     47GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
133Q9C5P0    755   SUVH8_ARATH Histone-lysine N-methyltransferas...2010.0000000004     67     26     40GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0040029; P:regulation of gene expression, epigenetic; TAS:TAIR.
134C6KTD2    6753   HKNMT_PLAF7 Putative histone-lysine N-methylt...1320.0000000007     66.6     33     51
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
135Q498E6    336   SET8B_XENLA N-lysine methyltransferase SETD8-...1150.000000001     63.9     35     50GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
136Q297V5    691   SETD8_DROPS Histone-lysine N-methyltransferas...1120.000000002     64.3     34     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005700; C:polytene chromosome; ISS:UniProtKB.
GO:0042799; F:histone methyltransferase activity (H4-K20 specific); ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
137Q9FF80    670   SUVH1_ARATH Histone-lysine N-methyltransferas...2320.000000002     64.3     27     42GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0042393; F:histone binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0040029; P:regulation of gene expression, epigenetic; TAS:TAIR.
138Q08AY6    335   SET8A_XENLA N-lysine methyltransferase SETD8-...1150.000000007     62     34     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
139Q8GZB6    624   SUVH4_ARATH Histone-lysine N-methyltransferas...1910.00000001     62     28     42GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0010385; F:double-stranded methylated DNA binding; IDA:TAIR.::GO:0042393; F:histone binding; IEA:InterPro.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:TAIR.::GO:0008327; F:methyl-CpG binding; IDA:TAIR.::GO:0010428; F:methyl-CpNpG binding; IDA:TAIR.::GO:0010429; F:methyl-CpNpN binding; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010216; P:maintenance of DNA methylation; IDA:TAIR.
140Q0V9E9    336   SETD8_XENTR N-lysine methyltransferase SETD8 ...1150.00000002     60.1     34     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
141Q6INA9    1269   SETB1_XENLA Histone-lysine N-methyltransferas...1750.0005     47.4     26     41GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
142Q9VFK6    691   SETD8_DROME Histone-lysine N-methyltransferas...1120.00000003     60.8     31     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005700; C:polytene chromosome; IDA:FlyBase.
GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IMP:FlyBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030261; P:chromosome condensation; IDA:FlyBase.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0034771; P:histone H4-K20 monomethylation; IMP:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
143Q08BR4    1216   STB1B_DANRE Histone-lysine N-methyltransferas...690.092     40     30     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
144O88974    1307   SETB1_MOUSE Histone-lysine N-methyltransferas...690.019     42.4     32     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
145Q15047    1291   SETB1_HUMAN Histone-lysine N-methyltransferas...690.03     41.6     32     54GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
146Q1L8U8    1436   STB1A_DANRE Histone-lysine N-methyltransferas...1680.001     45.8     26     40GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
147Q9C0A6    1442   SETD5_HUMAN SET domain-containing protein 5 O...1560.0000003     57.8     28     47
148Q5XJV7    1441   SETD5_MOUSE SET domain-containing protein 5 O...1110.0000009     56.2     32     50
149P34544    1300   MET2_CAEEL Probable histone-lysine N-methyltr...750.00005     50.8     40     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007276; P:gamete generation; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0010452; P:histone H3-K36 methylation; IMP:WormBase.::GO:0051567; P:histone H3-K9 methylation; IMP:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.
150Q071E0    344   SET8A_DANRE N-lysine methyltransferase SETD8-...1120.000002     53.9     30     47GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
151Q3UG20    1868   MLL5_MOUSE Histone-lysine N-methyltransferase...1320.000002     55.1     30     49GO:0070688; C:MLL5-L complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0042800; F:histone methyltransferase activity (H3-K4 specific); ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; ISS:BHF-UCL.::GO:0006306; P:DNA methylation; IMP:UniProtKB.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0042119; P:neutrophil activation; IMP:UniProtKB.::GO:0002446; P:neutrophil mediated immunity; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0048384; P:retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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