Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL164C
Length:
397
Number of sequences:
5887
Description:
YJL164C TPK1 SGDID:S000003700, Chr X from 111159-109966, Genome Release 64-1-1, reverse complement, Verified ORF, "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
811Q9QYZ4    484   SMOK1_MOUSE Sperm motility kinase 1 OS=Mus mu...2591e-30     125     29     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
812A7TIZ4    994   ATG1_VANPO Serine/threonine-protein kinase at...3251e-30     128     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
813Q9UEE5    414   ST17A_HUMAN Serine/threonine-protein kinase 1...2642e-30     125     26     50GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
814Q6SA08    328   TSSK4_HUMAN Testis-specific serine/threonine-...2832e-30     123     27     53
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032793; P:positive regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
815O14936    926   CSKP_HUMAN Peripheral plasma membrane protein...2762e-30     128     27     51GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0060170; C:cilium membrane; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005652; C:nuclear lamina; IDA:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0005730; C:nucleolus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; ISS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0001953; P:negative regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0090288; P:negative regulation of cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0010839; P:negative regulation of keratinocyte proliferation; IMP:BHF-UCL.::GO:0061045; P:negative regulation of wound healing; IMP:BHF-UCL.
816O70589    926   CSKP_MOUSE Peripheral plasma membrane protein...2762e-30     128     27     51GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0045202; C:synapse; IDA:MGI.::GO:0019717; C:synaptosome; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
817Q38871    556   CDPK5_ARATH Calcium-dependent protein kinase ...2672e-30     126     29     50GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009737; P:response to abscisic acid stimulus; IDA:TAIR.
818Q6DE87    474   CHK1_XENLA Serine/threonine-protein kinase Ch...3072e-30     125     27     49GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB.
819Q62915    909   CSKP_RAT Peripheral plasma membrane protein C...2762e-30     128     27     51GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; TAS:RGD.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IMP:RGD.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; TAS:RGD.
GO:0006886; P:intracellular protein transport; IMP:RGD.::GO:0006461; P:protein complex assembly; TAS:RGD.
820Q9URY1    672   PPK16_SCHPO Serine/threonine-protein kinase p...2662e-30     127     30     53GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; NAS:PomBase.
821O35942    443   NEK2_MOUSE Serine/threonine-protein kinase Ne...2922e-30     125     28     51GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0000794; C:condensed nuclear chromosome; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:MGI.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0000070; P:mitotic sister chromatid segregation; IMP:MGI.::GO:0043392; P:negative regulation of DNA binding; IDA:MGI.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.
822Q23551    7158   UNC22_CAEEL Twitchin OS=Caenorhabditis elegan...2832e-30     129     28     48GO:0031672; C:A band; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
823A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...2592e-30     125     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
824P97756    505   KKCC1_RAT Calcium/calmodulin-dependent protei...3012e-30     125     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0032147; P:activation of protein kinase activity; IDA:RGD.
825Q9H1R3    596   MYLK2_HUMAN Myosin light chain kinase 2, skel...2633e-30     125     29     50GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0030017; C:sarcomere; IC:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; ISS:BHF-UCL.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; IDA:BHF-UCL.
GO:0060048; P:cardiac muscle contraction; IC:BHF-UCL.::GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0032971; P:regulation of muscle filament sliding; IDA:BHF-UCL.::GO:0035914; P:skeletal muscle cell differentiation; IDA:UniProtKB.
826Q61RA2    493   CHK1_CAEBR Serine/threonine-protein kinase ch...2683e-30     124     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
827P49138    386   MAPK2_MOUSE MAP kinase-activated protein kina...2703e-30     124     33     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IMP:UniProtKB.::GO:0048839; P:inner ear development; IDA:MGI.::GO:0044351; P:macropinocytosis; IMP:UniProtKB.::GO:0032675; P:regulation of interleukin-6 production; IMP:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; IMP:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IMP:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB.
828Q96PN8    268   TSSK3_HUMAN Testis-specific serine/threonine-...2683e-30     121     31     52
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
829Q8RXT4    555   NEK4_ARATH Serine/threonine-protein kinase Ne...2963e-30     125     26     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
830P53355    1430   DAPK1_HUMAN Death-associated protein kinase 1...2733e-30     127     32     50GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0006915; P:apoptotic process; IGI:MGI.::GO:0008624; P:induction of apoptosis by extracellular signals; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:UniProtKB.
831P07934    388   PHKG1_MOUSE Phosphorylase b kinase gamma cata...2254e-30     123     32     53GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
832P13286    388   PHKG1_RAT Phosphorylase b kinase gamma cataly...2254e-30     123     32     53GO:0005964; C:phosphorylase kinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IDA:RGD.::GO:0004689; F:phosphorylase kinase activity; IDA:RGD.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
833Q6ZWH5    1172   NEK10_HUMAN Serine/threonine-protein kinase N...2594e-30     127     33     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
834P07313    608   MYLK2_RABIT Myosin light chain kinase 2, skel...2684e-30     125     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:BHF-UCL.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; IDA:BHF-UCL.
GO:0032971; P:regulation of muscle filament sliding; IC:BHF-UCL.
835Q9HC98    313   NEK6_HUMAN Serine/threonine-protein kinase Ne...2594e-30     122     29     53GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000772; P:regulation of cellular senescence; TAS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB.
836Q5R8Z4    681   PAK6_PONAB Serine/threonine-protein kinase PA...2584e-30     126     28     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
837Q9NQU5    681   PAK6_HUMAN Serine/threonine-protein kinase PA...2584e-30     126     28     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.
838Q8C0P0    865   GWL_MOUSE Serine/threonine-protein kinase gre...1330.000000000000005     80.5     32     54GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0034048; P:negative regulation of protein phosphatase type 2A activity; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.
839Q8C0X8    640   SMKX_MOUSE Sperm motility kinase X OS=Mus mus...2855e-30     125     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
840P0CY24    1228   STE20_CANAL Serine/threonine-protein kinase C...2505e-30     127     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001410; P:chlamydospore formation; IMP:CGD.::GO:0000747; P:conjugation with cellular fusion; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0000165; P:MAPK cascade; IGI:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0001558; P:regulation of cell growth; IGI:CGD.
841O02827    438   MYLK_SHEEP Myosin light chain kinase, smooth ...2445e-30     123     30     52GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
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