Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL141C
Length:
807
Number of sequences:
5887
Description:
YJL141C YAK1 SGDID:S000003677, Chr X from 150390-147967, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
571Q03043    1088   KGP24_DROME cGMP-dependent protein kinase, is...2516e-17     89.4     27     49GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.
GO:0046959; P:habituation; IMP:FlyBase.::GO:0030536; P:larval feeding behavior; IMP:UniProtKB.::GO:0008345; P:larval locomotory behavior; IMP:FlyBase.::GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0008016; P:regulation of heart contraction; IMP:FlyBase.::GO:0032095; P:regulation of response to food; IMP:FlyBase.::GO:0009744; P:response to sucrose stimulus; IDA:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.
572O22040    666   ANP1_ARATH Mitogen-activated protein kinase k...2287e-17     89     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0009908; P:flower development; IGI:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR.
573P42818    465   KPK1_ARATH Serine/threonine-protein kinase At...2417e-17     87.8     28     47GO:0005737; C:cytoplasm; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
574P28178    479   PK2_DICDI Protein kinase 2 OS=Dictyostelium d...2077e-17     87.8     27     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
575Q01389    1478   BCK1_YEAST Serine/threonine-protein kinase BC...2097e-17     89.4     31     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0001101; P:response to acid; IMP:SGD.::GO:0007584; P:response to nutrient; IMP:SGD.
576Q8IU85    385   KCC1D_HUMAN Calcium/calmodulin-dependent prot...2027e-17     87     32     51GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0032793; P:positive regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090023; P:positive regulation of neutrophil chemotaxis; ISS:UniProtKB.::GO:0050766; P:positive regulation of phagocytosis; IMP:UniProtKB.::GO:0060267; P:positive regulation of respiratory burst; IMP:UniProtKB.::GO:0050773; P:regulation of dendrite development; IMP:UniProtKB.::GO:0071622; P:regulation of granulocyte chemotaxis; IMP:UniProtKB.
577Q2TBL8    361   CDK10_BOVIN Cyclin-dependent kinase 10 OS=Bos...2257e-17     86.7     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
578O60285    661   NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS...2237e-17     88.6     28     51GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; IDA:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
579Q9JM52    1308   MINK1_MOUSE Misshapen-like kinase 1 OS=Mus mu...2178e-17     89.4     29     50GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0007268; P:synaptic transmission; ISS:UniProtKB.
580O55173    559   PDPK1_RAT 3-phosphoinositide-dependent protei...2198e-17     88.2     30     49GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.
GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
581O15530    556   PDPK1_HUMAN 3-phosphoinositide-dependent prot...2199e-17     88.2     30     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
582A5GFW1    402   AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)...2179e-17     87     31     51GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
583P34103    992   PK4_DICDI Protein kinase 4 OS=Dictyostelium d...2209e-17     89     26     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
584P36582    988   PCK1_SCHPO Protein kinase C-like 1 OS=Schizos...2491e-16     88.6     29     50GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004697; F:protein kinase C activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.
585Q8BWD8    501   CDK19_MOUSE Cyclin-dependent kinase 19 OS=Mus...2451e-16     87.4     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
586Q4FCZ5    450   SSN3_GIBMO Serine/threonine-protein kinase SS...2511e-16     87     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
587Q9NRP7    1315   STK36_HUMAN Serine/threonine-protein kinase 3...2241e-16     88.6     27     51GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0000287; F:magnesium ion binding; IC:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IDA:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.
588P32491    506   MKK2_YEAST MAP kinase kinase MKK2/SSP33 OS=Sa...2051e-16     87.4     32     50GO:0005622; C:intracellular; TAS:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0030242; P:peroxisome degradation; IGI:SGD.::GO:0007165; P:signal transduction; IMP:SGD.
589Q9BWU1    502   CDK19_HUMAN Cyclin-dependent kinase 19 OS=Hom...2451e-16     87.4     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
590Q9XTG7    528   AKT2_CAEEL Serine/threonine-protein kinase ak...2301e-16     87.4     30     50GO:0005622; C:intracellular; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.
GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; IMP:WormBase.
591Q09595    363   YRL5_CAEEL Putative serine/threonine-protein ...2261e-16     85.9     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
592Q6CR51    593   SSN3_KLULA Serine/threonine-protein kinase SS...2241e-16     87.8     28     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
593Q7YRC6    344   AURKB_BOVIN Aurora kinase B OS=Bos taurus (Bo...2241e-16     85.5     30     48GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
594Q9UIK4    370   DAPK2_HUMAN Death-associated protein kinase 2...2491e-16     85.9     29     47GO:0034423; C:autophagic vacuole lumen; IEA:UniProtKB-SubCell.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:ProtInc.::GO:0042802; F:identical protein binding; IPI:IntAct.
GO:0043276; P:anoikis; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.
595Q25378    658   KPC1_LYTPI Protein kinase C OS=Lytechinus pic...2442e-16     87.4     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
596Q2TA06    402   AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo...2202e-16     86.3     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
597Q1LUA6    3028   TRIO_DANRE Triple functional domain protein O...2342e-16     88.2     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
598Q4KM47    358   CDK10_RAT Cyclin-dependent kinase 10 OS=Rattu...2252e-16     85.5     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
599Q6A1A2    396   PDPK2_HUMAN Putative 3-phosphoinositide-depen...2192e-16     85.9     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
600P36005    433   KDX1_YEAST Serine/threonine-protein kinase KD...1492e-16     86.3     35     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
601P18334    360   CSK2A_CAEEL Casein kinase II subunit alpha OS...2132e-16     85.1     29     51GO:0030424; C:axon; IDA:UniProtKB.::GO:0005929; C:cilium; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0034606; P:response to hermaphrodite contact; IMP:WormBase.::GO:0034608; P:vulval location; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
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