Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL141C
Length:
807
Number of sequences:
5887
Description:
YJL141C YAK1 SGDID:S000003677, Chr X from 150390-147967, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511Q0TWJ7    443   SSN3_PHANO Serine/threonine-protein kinase SS...2542e-18     92.4     29     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
512Q55GS4    366   CDK10_DICDI Probable cyclin-dependent kinase ...2352e-18     91.3     30     49GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
513Q8SRF5    265   Y823_ENCCU Probable cell division protein kin...2232e-18     90.5     31     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
514Q04770    291   CDK2_ENTHI Cell division protein kinase 2 hom...2192e-18     90.5     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
515O15264    365   MK13_HUMAN Mitogen-activated protein kinase 1...3432e-18     91.3     23     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
516Q0IHQ8    951   STK10_XENTR Serine/threonine-protein kinase 1...2823e-18     93.6     27     46GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
517Q6CRA9    645   BUR1_KLULA Serine/threonine-protein kinase BU...2583e-18     92.8     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
518B7ZR30    950   STK10_XENLA Serine/threonine-protein kinase 1...2863e-18     93.2     27     47GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
519Q8SRU0    319   CSK2A_ENCCU Probable casein kinase II subunit...2325e-18     89.7     28     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
520P23293    657   BUR1_YEAST Serine/threonine-protein kinase BU...2415e-18     92.4     30     47GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005634; C:nucleus; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:SGD.
GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IDA:SGD.
521Q9TVL3    478   CDK9_CAEEL Probable cyclin-dependent kinase 9...2366e-18     91.3     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006479; P:protein methylation; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
522P83510    1323   TNIK_MOUSE Traf2 and NCK-interacting protein ...2157e-18     92.8     29     52GO:0005856; C:cytoskeleton; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0007256; P:activation of JNKK activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
523Q6FKC6    567   SSN3_CANGA Serine/threonine-protein kinase SS...1887e-18     91.7     32     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
524Q32MK0    819   MYLK3_HUMAN Putative myosin light chain kinas...2607e-18     92     28     48GO:0005829; C:cytosol; ISS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; ISS:BHF-UCL.
GO:0055003; P:cardiac myofibril assembly; ISS:BHF-UCL.::GO:0071347; P:cellular response to interleukin-1; IMP:BHF-UCL.::GO:0060298; P:positive regulation of sarcomere organization; ISS:BHF-UCL.::GO:0002528; P:regulation of vascular permeability involved in acute inflammatory response; IMP:BHF-UCL.::GO:0045214; P:sarcomere organization; ISS:BHF-UCL.::GO:0048769; P:sarcomerogenesis; ISS:BHF-UCL.
525Q75D46    753   BUR1_ASHGO Serine/threonine-protein kinase BU...2588e-18     92     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
526Q7ZX42    376   CDK9B_XENLA Cyclin-dependent kinase 9-B OS=Xe...2478e-18     89.7     29     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
527Q23356    1096   MIG15_CAEEL Serine/threonine-protein kinase m...2198e-18     92.4     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IGI:WormBase.::GO:0033563; P:dorsal/ventral axon guidance; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
528Q9UKE5    1360   TNIK_HUMAN TRAF2 and NCK-interacting protein ...2158e-18     92.4     29     52GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0007256; P:activation of JNKK activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
529Q6FQ83    667   BUR1_CANGA Serine/threonine-protein kinase BU...2651e-17     91.7     28     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
530Q5RDG7    819   MYLK3_PONAB Putative myosin light chain kinas...2601e-17     91.7     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
531F1LP90    1336   MINK1_RAT Misshapen-like kinase 1 OS=Rattus n...2371e-17     92     29     49GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0048813; P:dendrite morphogenesis; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; IMP:UniProtKB.
532Q9M077    294   AUR1_ARATH Serine/threonine-protein kinase Au...2511e-17     88.2     28     49GO:0009504; C:cell plate; IDA:TAIR.::GO:0005874; C:microtubule; IDA:TAIR.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IDA:TAIR.
533Q2PJ68    463   SGK1_CAEEL Serine/threonine-protein kinase sg...2181e-17     90.1     32     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
534O08815    1206   SLK_RAT STE20-like serine/threonine-protein k...2541e-17     91.7     27     47GO:0005737; C:cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:RGD.
535O45818    1070   DKF2_CAEEL Serine/threonine-protein kinase dk...2431e-17     91.7     29     51GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0045089; P:positive regulation of innate immune response; IMP:WormBase.
536Q6P3N6    464   CDK8_XENTR Cyclin-dependent kinase 8 OS=Xenop...2532e-17     90.1     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
537Q55FT4    2247   TSUA_DICDI Probable serine/threonine-protein ...2122e-17     91.7     32     53GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase.
538A8XQD5    1191   DKF2_CAEBR Serine/threonine-protein kinase dk...2832e-17     91.3     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
539A4QXX4    499   SSN3_MAGO7 Serine/threonine-protein kinase SS...2532e-17     90.1     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
540Q9H2G2    1235   SLK_HUMAN STE20-like serine/threonine-protein...2552e-17     91.3     28     47GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
541Q3UIZ8    795   MYLK3_MOUSE Putative myosin light chain kinas...2582e-17     90.5     27     48GO:0005737; C:cytoplasm; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; IDA:BHF-UCL.
GO:0045214; P:sarcomere organization; IDA:BHF-UCL.
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