UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YJL138C

Length:

395

Number of sequences:

5887

Description:

YJL138C TIF2 SGDID:S000003674, Chr X from 154691-153504, Genome Release 64-1-1, reverse complement, Verified ORF, "Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
271	Q6G7M9	506	Y1985_STAAS Probable DEAD-box ATP-dependent R...	355	1e-75	249	37	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
272	Q7A4G0	506	Y1885_STAAN Probable DEAD-box ATP-dependent R...	355	1e-75	249	37	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
273	Q6GEZ3	506	Y2168_STAAR Probable DEAD-box ATP-dependent R...	355	1e-75	249	37	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
274	Q5U216	427	DX39A_RAT ATP-dependent RNA helicase DDX39A O...	373	1e-75	247	36	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
275	Q2YUH3	506	Y1965_STAAB Probable DEAD-box ATP-dependent R...	355	1e-75	249	37	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
276	P44586	613	DEAD_HAEIN Cold-shock DEAD box protein A homo...	379	2e-74	249	37	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
277	Q5HME0	509	Y1688_STAEQ Probable DEAD-box ATP-dependent R...	365	3e-74	246	36	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
278	Q4L7W0	503	Y956_STAHJ Probable DEAD-box ATP-dependent RN...	355	4e-74	245	37	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
279	Q18212	425	DX39B_CAEEL Spliceosome RNA helicase DDX39B h...	373	7e-74	243	36	57	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
280	Q5ASK8	434	SUB2_EMENI ATP-dependent RNA helicase sub2 OS...	374	9e-74	243	37	56	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
281	Q8CRP6	509	Y1679_STAES Probable DEAD-box ATP-dependent R...	365	9e-74	244	36	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
282	Q6FL17	439	SUB2_CANGA ATP-dependent RNA helicase SUB2 OS...	411	1e-73	243	35	54	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
283	Q27268	424	DX39B_DROME ATP-dependent RNA helicase WM6 OS...	374	2e-73	241	37	57	GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; ISS:FlyBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:FlyBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0006406; P:mRNA export from nucleus; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:FlyBase.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
284	A7TJT7	442	SUB22_VANPO ATP-dependent RNA helicase SUB2-2...	383	3e-73	241	35	56	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
285	A6ZXP4	446	SUB2_YEAS7 ATP-dependent RNA helicase SUB2 OS...	383	4e-73	241	36	56	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
286	Q07478	446	SUB2_YEAST ATP-dependent RNA helicase SUB2 OS...	383	4e-73	241	36	56	GO:0000781; C:chromosome, telomeric region; IPI:SGD.::GO:0005681; C:spliceosomal complex; TAS:SGD.::GO:0000346; C:transcription export complex; IPI:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IGI:SGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0006406; P:mRNA export from nucleus; IDA:SGD.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:SGD.
287	Q8K9H6	601	DEAD_BUCAP Cold-shock DEAD box protein A homo...	365	6e-73	244	37	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
288	P57453	601	DEAD_BUCAI Cold-shock DEAD box protein A homo...	365	9e-73	244	37	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
289	P0C218	761	DDX20_DANRE Probable ATP-dependent RNA helica...	407	2e-72	247	36	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
290	A7TLA0	441	SUB21_VANPO ATP-dependent RNA helicase SUB2-1...	383	4e-72	238	35	56	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
291	Q89AF9	602	DEAD_BUCBP Cold-shock DEAD box protein A homo...	366	2e-71	241	37	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
292	Q759L6	438	SUB2_ASHGO ATP-dependent RNA helicase SUB2 OS...	383	4e-71	236	35	55	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
293	Q9UHI6	824	DDX20_HUMAN Probable ATP-dependent RNA helica...	381	6e-71	243	36	56	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0000244; P:assembly of spliceosomal tri-snRNP; TAS:ProtInc.::GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
294	Q6CM95	437	SUB2_KLULA ATP-dependent RNA helicase SUB2 OS...	383	1e-70	234	34	55	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
295	Q9JJY4	825	DDX20_MOUSE Probable ATP-dependent RNA helica...	350	7e-70	240	37	57	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0017053; C:transcriptional repressor complex; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006917; P:induction of apoptosis; IPI:MGI.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
296	P25888	454	RHLE_ECOLI ATP-dependent RNA helicase rhlE OS...	370	1e-68	229	34	56	GO:0005840; C:ribosome; IDA:EcoCyc.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IDA:EcoCyc.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
297	Q4PHU9	552	DBP2_USTMA ATP-dependent RNA helicase DBP2 OS...	384	1e-68	232	36	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
298	Q8W4R3	591	RH30_ARATH DEAD-box ATP-dependent RNA helicas...	383	8e-68	231	34	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
299	Q9C718	501	RH20_ARATH DEAD-box ATP-dependent RNA helicas...	385	2e-67	228	34	55	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
300	Q10RI7	505	RH38_ORYSJ DEAD-box ATP-dependent RNA helicas...	409	3e-67	227	36	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
301	Q5QMN3	494	RH20_ORYSJ DEAD-box ATP-dependent RNA helicas...	367	9e-67	226	35	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.

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