UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YJL130C

Length:

2214

Number of sequences:

5887

Description:

YJL130C URA2 SGDID:S000003666, Chr X from 172367-165723, Genome Release 64-1-1, reverse complement, Verified ORF, "Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
931	A0RHR1	306	PYRB_BACAH Aspartate carbamoyltransferase OS=...	263	6e-33	137	36	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
932	Q6FCR5	338	PYRB_ACIAD Aspartate carbamoyltransferase OS=...	317	6e-33	137	33	47
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
933	Q5FGW9	297	PYRB_EHRRG Aspartate carbamoyltransferase OS=...	274	6e-33	136	35	53
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
934	Q732I0	304	PYRB_BACC1 Aspartate carbamoyltransferase OS=...	263	8e-33	136	36	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
935	Q48P93	334	PYRB_PSE14 Aspartate carbamoyltransferase OS=...	311	9e-33	137	33	48
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
936	A8FD14	307	PYRB_BACP2 Aspartate carbamoyltransferase OS=...	278	1e-32	136	33	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
937	Q7NCV1	329	PYRB_GLOVI Aspartate carbamoyltransferase OS=...	330	1e-32	137	33	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
938	P65613	319	PYRB_MYCTU Aspartate carbamoyltransferase OS=...	315	1e-32	136	32	49	GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
939	A5U282	319	PYRB_MYCTA Aspartate carbamoyltransferase OS=...	315	1e-32	136	32	49
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
940	C1AN25	319	PYRB_MYCBT Aspartate carbamoyltransferase OS=...	315	1e-32	136	32	49
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
941	A1KIG9	319	PYRB_MYCBP Aspartate carbamoyltransferase OS=...	315	1e-32	136	32	49
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
942	P65614	319	PYRB_MYCBO Aspartate carbamoyltransferase OS=...	315	1e-32	136	32	49
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
943	Q1GZG8	317	PYRB_METFK Aspartate carbamoyltransferase OS=...	312	1e-32	136	32	51
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
944	B8DDR4	303	PYRB_LISMH Aspartate carbamoyltransferase OS=...	261	1e-32	136	33	52
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
945	Q2Y651	316	PYRB_NITMU Aspartate carbamoyltransferase OS=...	276	1e-32	136	35	51
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
946	A0JX76	337	PYRB_ARTS2 Aspartate carbamoyltransferase OS=...	327	1e-32	136	33	49
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
947	A1U761	336	PYRB_MARAV Aspartate carbamoyltransferase OS=...	282	1e-32	136	35	52
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
948	Q4ZZ70	334	PYRB_PSEU2 Aspartate carbamoyltransferase OS=...	311	1e-32	136	33	48
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
949	B7IUP9	304	PYRB_BACC2 Aspartate carbamoyltransferase OS=...	263	1e-32	135	35	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
950	Q87V99	334	PYRB_PSESM Aspartate carbamoyltransferase OS=...	312	2e-32	136	33	48
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
951	C5CCF5	327	PYRB_MICLC Aspartate carbamoyltransferase OS=...	328	2e-32	135	33	47
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
952	Q8PII1	315	PYRB_XANAC Aspartate carbamoyltransferase OS=...	319	3e-32	135	34	52
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
953	B9MS21	305	PYRB_ANATD Aspartate carbamoyltransferase OS=...	307	3e-32	135	31	51
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
954	C0QJ55	312	PYRB_DESAH Aspartate carbamoyltransferase OS=...	313	3e-32	135	31	49
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
955	B2HNE6	320	PYRB_MYCMM Aspartate carbamoyltransferase OS=...	317	3e-32	135	33	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
956	Q3AC00	312	PYRB_CARHZ Aspartate carbamoyltransferase OS=...	311	3e-32	135	31	53
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
957	Q2JTU8	326	PYRB_SYNJA Aspartate carbamoyltransferase OS=...	323	3e-32	135	32	51
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
958	A6T290	319	PYRB_JANMA Aspartate carbamoyltransferase OS=...	317	3e-32	135	32	51
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
959	B1VDM8	314	PYRB_CORU7 Aspartate carbamoyltransferase OS=...	272	4e-32	134	35	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
960	A1UT24	321	PYRB_BARBK Aspartate carbamoyltransferase OS=...	320	5e-32	134	33	48
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
961	A0PPI8	320	PYRB_MYCUA Aspartate carbamoyltransferase OS=...	317	5e-32	134	33	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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