UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YJL130C

Length:

2214

Number of sequences:

5887

Description:

YJL130C URA2 SGDID:S000003666, Chr X from 172367-165723, Genome Release 64-1-1, reverse complement, Verified ORF, "Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
511	A6VHS2	302	PYRB_METM7 Aspartate carbamoyltransferase OS=...	301	8e-67	235	41	65
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
512	Q9JXX4	377	CARA_NEIMB Carbamoyl-phosphate synthase small...	394	8e-67	238	39	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
513	O19886	399	CARA_CYACA Carbamoyl-phosphate synthase small...	409	1e-66	238	37	55	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
514	Q1XDT6	384	CARA_PORYE Carbamoyl-phosphate synthase small...	397	1e-66	238	38	55	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
515	B5F9P9	309	PYRB_VIBFM Aspartate carbamoyltransferase OS=...	309	1e-66	235	39	63
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
516	Q5E7U5	309	PYRB_VIBF1 Aspartate carbamoyltransferase OS=...	309	1e-66	235	39	63
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
517	P58896	375	CARA_XANCP Carbamoyl-phosphate synthase small...	394	2e-66	237	37	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
518	A8MAC7	306	PYRB_CALMQ Aspartate carbamoyltransferase OS=...	304	2e-66	234	43	62
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
519	Q8G655	320	PYRB_BIFLO Aspartate carbamoyltransferase OS=...	274	2e-66	235	44	64
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
520	B3DS61	320	PYRB_BIFLD Aspartate carbamoyltransferase OS=...	274	2e-66	235	44	64
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
521	B5FSF3	311	PYRB_SALDC Aspartate carbamoyltransferase OS=...	315	2e-66	234	41	61
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
522	B7GRV4	320	PYRB_BIFLS Aspartate carbamoyltransferase OS=...	274	2e-66	234	44	64
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
523	P38098	378	CARA_PSEAE Carbamoyl-phosphate synthase small...	395	3e-66	236	37	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
524	Q8XZ85	378	CARA_RALSO Carbamoyl-phosphate synthase small...	395	3e-66	236	37	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
525	A0RXJ5	309	PYRB_CENSY Aspartate carbamoyltransferase OS=...	304	4e-66	234	40	61
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
526	A8G961	311	PYRB_SERP5 Aspartate carbamoyltransferase OS=...	315	4e-66	234	41	60
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
527	Q6B940	395	CARA_GRATL Carbamoyl-phosphate synthase small...	403	5e-66	236	36	54	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
528	A3DM48	311	PYRB_STAMF Aspartate carbamoyltransferase OS=...	302	5e-66	233	41	62
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
529	A1SZR6	311	PYRB_PSYIN Aspartate carbamoyltransferase OS=...	302	6e-66	233	40	62
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
530	A6UWP3	314	PYRB_META3 Aspartate carbamoyltransferase OS=...	304	6e-66	233	41	64
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
531	Q6NH15	379	CARA_CORDI Carbamoyl-phosphate synthase small...	401	7e-66	235	38	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
532	Q9YBD4	308	PYRB_AERPE Aspartate carbamoyltransferase OS=...	310	8e-66	233	42	60
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
533	A9A2Q5	309	PYRB_NITMS Aspartate carbamoyltransferase OS=...	308	1e-65	232	40	61
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
534	Q8KGA2	366	CARA_CHLTE Carbamoyl-phosphate synthase small...	400	1e-65	234	37	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
535	A6THH4	311	PYRB_KLEP7 Aspartate carbamoyltransferase OS=...	318	1e-65	232	40	60
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
536	B5Y2U6	311	PYRB_KLEP3 Aspartate carbamoyltransferase OS=...	318	1e-65	232	40	60
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
537	B9LND9	313	PYRB_HALLT Aspartate carbamoyltransferase OS=...	304	2e-65	231	41	60
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
538	Q6F8M7	379	CARA_ACIAD Carbamoyl-phosphate synthase small...	398	2e-65	234	36	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
539	Q1MPN3	376	CARA_LAWIP Carbamoyl-phosphate synthase small...	399	2e-65	234	37	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
540	A5UMP0	316	PYRB_METS3 Aspartate carbamoyltransferase OS=...	307	4e-65	231	41	60
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
541	P36838	353	CARX_BACSU Carbamoyl-phosphate synthase argin...	390	5e-65	232	37	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.

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