Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL128C
Length:
668
Number of sequences:
5887
Description:
YJL128C PBS2 SGDID:S000003664, Chr X from 180103-178097, Genome Release 64-1-1, reverse complement, Verified ORF, "MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
841P97504    651   BMX_MOUSE Cytoplasmic tyrosine-protein kinase...2674e-16     85.9     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
842Q810W7    1570   MAST1_RAT Microtubule-associated serine/threo...2634e-16     86.7     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
843Q5BKK4    418   SGK1_XENTR Serine/threonine-protein kinase Sg...2264e-16     84.7     30     47GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
844P23437    297   CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenop...2244e-16     83.2     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
845P05696    672   KPCA_RAT Protein kinase C alpha type OS=Rattu...2294e-16     85.9     28     48GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007568; P:aging; IEP:RGD.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:RGD.::GO:0045184; P:establishment of protein localization; TAS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045822; P:negative regulation of heart contraction; IMP:RGD.::GO:0017148; P:negative regulation of translation; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IDA:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:RGD.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0051965; P:positive regulation of synapse assembly; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0048259; P:regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0046677; P:response to antibiotic; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IMP:RGD.::GO:0045471; P:response to ethanol; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; IMP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
846P04409    672   KPCA_BOVIN Protein kinase C alpha type OS=Bos...2294e-16     85.9     28     48GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
847P10102    672   KPCA_RABIT Protein kinase C alpha type OS=Ory...2294e-16     85.9     28     48GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
848P0CP71    988   ATG1_CRYNB Serine/threonine-protein kinase AT...2454e-16     86.3     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
849Q42396    490   CDPKC_ARATH Calcium-dependent protein kinase ...2664e-16     85.1     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
850Q99558    947   M3K14_HUMAN Mitogen-activated protein kinase ...2064e-16     86.3     32     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004704; F:NF-kappaB-inducing kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0006955; P:immune response; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.
851P0CP70    988   ATG1_CRYNJ Serine/threonine-protein kinase AT...2454e-16     86.3     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
852P17252    672   KPCA_HUMAN Protein kinase C alpha type OS=Hom...2294e-16     85.9     28     48GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0035403; F:histone kinase activity (H3-T6 specific); IDA:UniProtKB.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0090330; P:regulation of platelet aggregation; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
853A2VDV2    465   STK38_BOVIN Serine/threonine-protein kinase 3...3144e-16     85.1     25     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.
854P24941    298   CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo ...2214e-16     83.2     28     48GO:0015030; C:Cajal body; IDA:UniProtKB.::GO:0005813; C:centrosome; TAS:UniProtKB.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071732; P:cellular response to nitric oxide; TAS:UniProtKB.::GO:0051298; P:centrosome duplication; TAS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000085; P:G2 phase of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.::GO:0016572; P:histone phosphorylation; IDA:GOC.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0007126; P:meiosis; TAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.::GO:0006275; P:regulation of DNA replication; TAS:ProtInc.::GO:0060968; P:regulation of gene silencing; IDA:UniProtKB.::GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
855Q6BRY2    330   PHO85_DEBHA Negative regulator of the PHO sys...3024e-16     83.6     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
856Q5R8M1    465   STK38_PONAB Serine/threonine-protein kinase 3...3144e-16     85.1     25     42GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.
857Q15208    465   STK38_HUMAN Serine/threonine-protein kinase 3...3144e-16     85.1     25     42GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0070688; C:MLL5-L complex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
858Q54UZ1    411   Y1639_DICDI Probable serine/threonine-protein...2604e-16     84.3     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
859Q9Y3S1    2297   WNK2_HUMAN Serine/threonine-protein kinase WN...2154e-16     86.7     32     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:2000651; P:positive regulation of sodium ion transmembrane transporter activity; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000021; P:regulation of ion homeostasis; IMP:UniProtKB.
860Q16816    387   PHKG1_HUMAN Phosphorylase b kinase gamma cata...2904e-16     84.3     30     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0006006; P:glucose metabolic process; TAS:Reactome.::GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; TAS:Reactome.
861Q8TDC3    778   BRSK1_HUMAN Serine/threonine-protein kinase B...2614e-16     85.9     24     47GO:0030054; C:cell junction; IDA:HPA.::GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB.
GO:0005524; F:ATP binding; IC:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0051298; P:centrosome duplication; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0007269; P:neurotransmitter secretion; ISS:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.
862Q7TPS0    764   KS6A6_MOUSE Ribosomal protein S6 kinase alpha...2915e-16     85.5     27     47GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045992; P:negative regulation of embryonic development; IDA:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:2000381; P:negative regulation of mesoderm development; IDA:UniProtKB.
863Q13555    558   KCC2G_HUMAN Calcium/calmodulin-dependent prot...2865e-16     85.5     24     45GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030073; P:insulin secretion; NAS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
864A1Z7T0    1190   PKN_DROME Serine/threonine-protein kinase N O...2685e-16     86.3     29     47GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007391; P:dorsal closure; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007472; P:wing disc morphogenesis; IMP:UniProtKB.
865P57059    783   SIK1_HUMAN Serine/threonine-protein kinase SI...2665e-16     85.9     27     45GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0055007; P:cardiac muscle cell differentiation; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.::GO:0072333; P:signal transduction by p53 class mediator resulting in induction of anoikis; IMP:BHF-UCL.
866P09324    541   YES_CHICK Tyrosine-protein kinase Yes OS=Gall...2555e-16     85.1     29     45GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
867Q0CLX3    964   ATG1_ASPTN Serine/threonine-protein kinase at...3225e-16     85.9     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
868Q8BHI9    436   NIM1_MOUSE Serine/threonine-protein kinase NI...2065e-16     84.7     31     49
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
869O00444    970   PLK4_HUMAN Serine/threonine-protein kinase PL...2735e-16     85.9     22     48GO:0005814; C:centriole; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0046601; P:positive regulation of centriole replication; IMP:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
870P00524    526   SRC_RSVSA Tyrosine-protein kinase transformin...2705e-16     85.1     30     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
871P00525    526   SRC_AVISR Tyrosine-protein kinase transformin...2705e-16     85.1     30     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
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