Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL128C
Length:
668
Number of sequences:
5887
Description:
YJL128C PBS2 SGDID:S000003664, Chr X from 180103-178097, Genome Release 64-1-1, reverse complement, Verified ORF, "MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541P53349    1493   M3K1_MOUSE Mitogen-activated protein kinase k...2782e-18     93.6     26     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL.
542P31751    481   AKT2_HUMAN RAC-beta serine/threonine-protein ...2902e-18     92     27     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0045444; P:fat cell differentiation; TAS:UniProtKB.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.::GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.::GO:0032000; P:positive regulation of fatty acid beta-oxidation; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0071156; P:regulation of cell cycle arrest; TAS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
543Q4R7T5    570   CDKL2_MACFA Cyclin-dependent kinase-like 2 OS...2962e-18     92.8     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
544Q60823    481   AKT2_MOUSE RAC-beta serine/threonine-protein ...2922e-18     92     27     48GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0032287; P:peripheral nervous system myelin maintenance; IMP:MGI.::GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IGI:MGI.::GO:0072659; P:protein localization in plasma membrane; IGI:MGI.::GO:0046328; P:regulation of JNK cascade; IDA:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
545Q6H9I1    952   ATG1_BOTFU Serine/threonine-protein kinase AT...3102e-18     93.2     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
546A6RYB8    952   ATG1_BOTFB Serine/threonine-protein kinase at...3102e-18     93.2     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
547Q61410    762   KGP2_MOUSE cGMP-dependent protein kinase 2 OS...2772e-18     93.2     31     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC.
548Q6GM53    743   IKKA_XENLA Inhibitor of nuclear factor kappa-...2092e-18     93.2     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008384; F:IkappaB kinase activity; IEA:EC.
549P49673    337   KAPC_ASCSU cAMP-dependent protein kinase cata...2892e-18     90.5     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC.
550Q8QZV4    488   ST32C_MOUSE Serine/threonine-protein kinase 3...2192e-18     92     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
551B4J3F1    762   PLK4_DROGR Serine/threonine-protein kinase PL...2753e-18     92.8     28     49GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
552Q8BG48    372   ST17B_MOUSE Serine/threonine-protein kinase 1...2843e-18     90.9     31     49GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
553Q8C078    588   KKCC2_MOUSE Calcium/calmodulin-dependent prot...3113e-18     92.4     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
554Q54PK9    908   PDPKB_DICDI 3-phosphoinositide-dependent prot...2733e-18     93.2     26     44
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
555Q9C958    361   SRK2B_ARATH Serine/threonine-protein kinase S...2783e-18     90.5     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IDA:TAIR.
556P54666    311   CC2H3_TRYBB Cell division control protein 2 h...2963e-18     89.7     28     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
557Q8IY84    436   NIM1_HUMAN Serine/threonine-protein kinase NI...2613e-18     91.3     27     44
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
558Q7TSE6    464   ST38L_MOUSE Serine/threonine-protein kinase 3...3103e-18     91.7     27     42GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0051128; P:regulation of cellular component organization; IDA:UniProtKB.
559Q7ZX15    486   AKT2A_XENLA RAC-beta serine/threonine-protein...2873e-18     92     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
560Q3E9C0    523   CDPKY_ARATH Calcium-dependent protein kinase ...2663e-18     92     29     47GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0080092; P:regulation of pollen tube growth; IMP:TAIR.
561Q16512    942   PKN1_HUMAN Serine/threonine-protein kinase N1...2703e-18     93.2     29     50GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0017049; F:GTP-Rho binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.::GO:0035402; F:histone kinase activity (H3-T11 specific); IDA:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB.::GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0010631; P:epithelial cell migration; IMP:UniProtKB.::GO:2000145; P:regulation of cell motility; IMP:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
562O74536    576   SNF1_SCHPO SNF1-like protein kinase ssp2 OS=S...2613e-18     92.4     28     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031593; F:polyubiquitin binding; TAS:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:2000766; P:negative regulation of cytoplasmic translation; ISS:PomBase.::GO:0046015; P:regulation of transcription by glucose; ISS:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
563P47197    481   AKT2_RAT RAC-beta serine/threonine-protein ki...2903e-18     91.7     27     48GO:0005829; C:cytosol; IDA:RGD.::GO:0032593; C:insulin-responsive compartment; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:RGD.::GO:0033119; P:negative regulation of RNA splicing; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0046326; P:positive regulation of glucose import; IMP:RGD.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:RGD.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:RGD.::GO:0050927; P:positive regulation of positive chemotaxis; IDA:RGD.::GO:0009967; P:positive regulation of signal transduction; IMP:RGD.::GO:0010765; P:positive regulation of sodium ion transport; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0043491; P:protein kinase B signaling cascade; IMP:RGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0014850; P:response to muscle activity; IEP:RGD.::GO:0006970; P:response to osmotic stress; IEP:RGD.
564Q9Z1M4    485   KS6B2_MOUSE Ribosomal protein S6 kinase beta-...2743e-18     91.7     31     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
565P23298    683   KPCL_MOUSE Protein kinase C eta type OS=Mus m...2423e-18     92.4     29     47GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; ISS:UniProtKB.
566B4NSS9    743   DCLK_DROSI Serine/threonine-protein kinase GD...2714e-18     92.4     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
567Q86SG6    692   NEK8_HUMAN Serine/threonine-protein kinase Ne...2714e-18     92.4     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
568Q64617    683   KPCL_RAT Protein kinase C eta type OS=Rattus ...2424e-18     92.4     29     47GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070528; P:protein kinase C signaling cascade; IMP:RGD.::GO:2000810; P:regulation of tight junction assembly; ISS:UniProtKB.
569Q96RG2    1323   PASK_HUMAN PAS domain-containing serine/threo...2924e-18     92.8     28     46GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0070092; P:regulation of glucagon secretion; ISS:UniProtKB.::GO:0043576; P:regulation of respiratory gaseous exchange; ISS:UniProtKB.
570A1A4I4    944   PKN1_BOVIN Serine/threonine-protein kinase N1...2704e-18     92.8     29     50GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0017049; F:GTP-Rho binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:UniProtKB.
GO:0010631; P:epithelial cell migration; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
571P51954    1203   NEK1_MOUSE Serine/threonine-protein kinase Ne...2674e-18     92.8     28     48GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:MGI.::GO:0010212; P:response to ionizing radiation; IMP:MGI.
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