Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL128C
Length:
668
Number of sequences:
5887
Description:
YJL128C PBS2 SGDID:S000003664, Chr X from 180103-178097, Genome Release 64-1-1, reverse complement, Verified ORF, "MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511O15021    2626   MAST4_HUMAN Microtubule-associated serine/thr...2831e-18     95.1     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
512Q8WNU8    637   NEK11_MACFA Serine/threonine-protein kinase N...2701e-18     94     30     46GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0031573; P:intra-S DNA damage checkpoint; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
513Q64595    762   KGP2_RAT cGMP-dependent protein kinase 2 OS=R...2771e-18     94     31     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC.
514Q13233    1512   M3K1_HUMAN Mitogen-activated protein kinase k...2781e-18     94.7     26     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
515P34099    648   KAPC_DICDI cAMP-dependent protein kinase cata...2651e-18     94     29     47GO:0005813; C:centrosome; TAS:dictyBase.::GO:0005829; C:cytosol; TAS:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004691; F:cAMP-dependent protein kinase activity; TAS:dictyBase.
GO:0031285; P:regulation of sorocarp stalk cell differentiation; IGI:dictyBase.::GO:0042173; P:regulation of sporulation resulting in formation of a cellular spore; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
516P34722    704   KPC1_CAEEL Protein kinase C-like 1 OS=Caenorh...2351e-18     94     29     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase.
517Q91XS8    371   ST17B_RAT Serine/threonine-protein kinase 17B...2841e-18     91.7     31     49GO:0015629; C:actin cytoskeleton; IMP:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.
518Q95KV1    740   IKKA_BOVIN Inhibitor of nuclear factor kappa-...2121e-18     94     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008384; F:IkappaB kinase activity; IEA:EC.
519P17157    305   PHO85_YEAST Cyclin-dependent protein kinase P...3021e-18     90.9     27     43GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.
520Q00078    1096   KPC1_ASPNG Protein kinase C-like OS=Aspergill...2691e-18     94.4     30     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
521Q5R754    493   CDKL2_PONAB Cyclin-dependent kinase-like 2 OS...2961e-18     93.2     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
522Q92772    493   CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS...2961e-18     93.2     27     44GO:0005813; C:centrosome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007548; P:sex differentiation; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
523Q9Y243    479   AKT3_HUMAN RAC-gamma serine/threonine-protein...2771e-18     92.8     28     47GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000002; P:mitochondrial genome maintenance; IMP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB.
524Q9WTR2    1291   M3K6_MOUSE Mitogen-activated protein kinase k...2021e-18     94.4     36     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
525Q8NG66    645   NEK11_HUMAN Serine/threonine-protein kinase N...2701e-18     93.6     30     46GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.
526Q5ZJH6    468   ULK3_CHICK Serine/threonine-protein kinase UL...2791e-18     92.8     28     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
527Q9W1B0    1637   GEK_DROME Serine/threonine-protein kinase Gen...2901e-18     94.4     28     46GO:0030424; C:axon; IDA:FlyBase.::GO:0030426; C:growth cone; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0008154; P:actin polymerization or depolymerization; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030833; P:regulation of actin filament polymerization; IMP:UniProtKB.::GO:0008039; P:synaptic target recognition; IMP:FlyBase.
528A2KF29    484   SMKTR_MOUSE Sperm motility kinase Tcr mutant ...2671e-18     92.8     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
529P87253    1142   KPC1_NEUCR Protein kinase C-like OS=1257 / FG...2701e-18     94.4     29     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
530A7F0W2    951   ATG1_SCLS1 Serine/threonine-protein kinase AT...3081e-18     94     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
531B4KYX8    778   PLK4_DROMO Serine/threonine-protein kinase PL...2741e-18     93.6     27     48GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
532Q16W24    769   PLK4_AEDAE Serine/threonine-protein kinase PL...2802e-18     93.6     25     48GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
533Q6FKD4    302   PHO85_CANGA Negative regulator of the PHO sys...3022e-18     90.5     28     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
534Q9WVL4    564   RK_MOUSE Rhodopsin kinase OS=Mus musculus (Mo...2592e-18     92.8     30     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:InterPro.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0022400; P:regulation of rhodopsin mediated signaling pathway; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
535Q5MPA9    767   DCLK2_RAT Serine/threonine-protein kinase DCL...3132e-18     93.6     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
536Q96PY6    1258   NEK1_HUMAN Serine/threonine-protein kinase Ne...2662e-18     94     27     48GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
537Q9Y2H1    464   ST38L_HUMAN Serine/threonine-protein kinase 3...3152e-18     92.4     27     43GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0051128; P:regulation of cellular component organization; ISS:UniProtKB.
538Q8TD19    979   NEK9_HUMAN Serine/threonine-protein kinase Ne...2812e-18     93.6     29     48GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
539Q8BGW6    398   ST32A_MOUSE Serine/threonine-protein kinase 3...2672e-18     91.3     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
540D3ZHP7    472   ULK3_RAT Serine/threonine-protein kinase ULK3...2782e-18     92     28     47GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
541P53349    1493   M3K1_MOUSE Mitogen-activated protein kinase k...2782e-18     93.6     26     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL.
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