Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL106W
Length:
645
Number of sequences:
5887
Description:
YJL106W IME2 SGDID:S000003642, Chr X from 221390-223327, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241P48734    297   CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos t...3663e-27     116     29     45GO:0030496; C:midbody; ISS:AgBase.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0005876; C:spindle microtubule; ISS:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006916; P:anti-apoptosis; ISS:AgBase.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
242P0C431    357   HOG1_GIBZE Mitogen-activated protein kinase H...3473e-27     117     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
243P49185    411   MK08_RAT Mitogen-activated protein kinase 8 O...2803e-27     118     29     46GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0031982; C:vesicle; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD.
GO:0006954; P:inflammatory response; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.::GO:0031175; P:neuron projection development; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IEP:RGD.::GO:0030335; P:positive regulation of cell migration; IDA:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0031116; P:positive regulation of microtubule polymerization; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:RGD.::GO:0009408; P:response to heat; IDA:RGD.::GO:0042542; P:response to hydrogen peroxide; IDA:RGD.::GO:0006970; P:response to osmotic stress; IDA:RGD.::GO:0048545; P:response to steroid hormone stimulus; IEP:RGD.
244P41808    388   SMK1_YEAST Sporulation-specific mitogen-activ...3673e-27     117     27     45GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:SGD.
GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0042174; P:negative regulation of sporulation resulting in formation of a cellular spore; IGI:SGD.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
245Q4W6D3    355   HOG1_COCHE Mitogen-activated protein kinase H...3554e-27     117     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
246Q91727    319   CDK4_XENLA Cyclin-dependent kinase 4 OS=Xenop...2824e-27     116     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
247Q8NJT7    359   HOG1_HORWE Mitogen-activated protein kinase H...2724e-27     117     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
248Q5VN19    570   MPK11_ORYSJ Mitogen-activated protein kinase ...2804e-27     119     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
249P18266    420   GSK3B_RAT Glycogen synthase kinase-3 beta OS=...2495e-27     117     26     48GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0048156; F:tau protein binding; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IDA:RGD.
GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; IDA:RGD.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0050774; P:negative regulation of dendrite morphogenesis; IMP:RGD.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:RGD.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.
250P34556    332   CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caeno...3755e-27     116     28     46GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:WormBase.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IMP:UniProtKB.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0001556; P:oocyte maturation; IMP:WormBase.::GO:0045836; P:positive regulation of meiosis; IMP:WormBase.::GO:0051446; P:positive regulation of meiotic cell cycle; IMP:UniProtKB.::GO:0035046; P:pronuclear migration; IMP:WormBase.
251P17157    305   PHO85_YEAST Cyclin-dependent protein kinase P...2245e-27     115     33     54GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.
252Q96WV9    591   CDK9_SCHPO Probable cyclin-dependent kinase 9...2875e-27     119     30     49GO:0070693; C:P-TEFb-cap methyltransferase complex; IDA:PomBase.::GO:0008024; C:positive transcription elongation factor complex b; NAS:PomBase.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:PomBase.
GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:PomBase.::GO:0034243; P:regulation of transcription elongation from RNA polymerase II promoter; IMP:PomBase.::GO:0006360; P:transcription from RNA polymerase I promoter; IGI:PomBase.
253Q9SJG9    606   MPK20_ARATH Mitogen-activated protein kinase ...2815e-27     119     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
254Q9VPC0    952   KP58_DROME Serine/threonine-protein kinase PI...2205e-27     120     33     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.
255Q6PWX2    358   HOG1_BEABA Mitogen-activated protein kinase H...3485e-27     116     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
256Q2WGK3    356   HOG1_TRIHA Mitogen-activated protein kinase h...3475e-27     116     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
257Q91757    420   GSK3B_XENLA Glycogen synthase kinase-3 beta O...3155e-27     117     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
258P06493    297   CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo ...3656e-27     115     29     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0007098; P:centrosome cycle; TAS:UniProtKB.::GO:0006281; P:DNA repair; TAS:UniProtKB.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0007344; P:pronuclear fusion; TAS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045995; P:regulation of embryonic development; TAS:UniProtKB.::GO:0014038; P:regulation of Schwann cell differentiation; TAS:UniProtKB.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
259Q6C7U8    294   PHO85_YARLI Negative regulator of the PHO sys...2726e-27     115     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
260Q39022    376   MPK2_ARATH Mitogen-activated protein kinase 2...2986e-27     117     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
261Q52PH6    355   HOG1_ALTBR Mitogen-activated protein kinase H...2736e-27     116     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
262Q336X9    376   MPK6_ORYSJ Mitogen-activated protein kinase 6...2647e-27     116     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
263Q5RCH1    297   CDK1_PONAB Cyclin-dependent kinase 1 OS=Pongo...3627e-27     115     28     44GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
264Q9LUC3    598   MPK19_ARATH Mitogen-activated protein kinase ...2847e-27     119     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
265Q8SW92    308   KIN28_ENCCU Probable serine/threonine-protein...3497e-27     115     27     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
266Q8QHK8    426   MK08_XENLA Mitogen-activated protein kinase 8...2197e-27     117     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
267Q7XUF4    710   CDKG2_ORYSJ Cyclin-dependent kinase G-2 OS=Or...2189e-27     119     34     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
268A2XUW1    710   CDKG2_ORYSI Cyclin-dependent kinase G-2 OS=Or...2189e-27     119     34     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
269Q8GYQ5    372   MPK12_ARATH Mitogen-activated protein kinase ...2649e-27     116     29     49GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0009734; P:auxin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0080026; P:response to indolebutyric acid stimulus; IMP:TAIR.
270Q39021    370   MPK1_ARATH Mitogen-activated protein kinase 1...2869e-27     116     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.
GO:0009734; P:auxin mediated signaling pathway; TAS:TAIR.
271O42781    351   MAPK2_PNECA Mitogen-activated protein kinase ...2791e-26     115     30     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0000751; P:cell cycle arrest in response to pheromone; NAS:UniProtKB.
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