Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL106W
Length:
645
Number of sequences:
5887
Description:
YJL106W IME2 SGDID:S000003642, Chr X from 221390-223327, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P24923    291   CDC21_MEDSA Cell division control protein 2 h...2533e-28     119     34     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
182P92208    372   JNK_DROME Stress-activated protein kinase JNK...3333e-28     120     30     44GO:0030424; C:axon; IDA:FlyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:FlyBase.
GO:0019731; P:antibacterial humoral response; IDA:FlyBase.::GO:0048675; P:axon extension; IMP:FlyBase.::GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IGI:FlyBase.::GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0048674; P:collateral sprouting of injured axon; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007391; P:dorsal closure; NAS:FlyBase.::GO:0001736; P:establishment of planar polarity; NAS:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0048803; P:imaginal disc-derived male genitalia morphogenesis; IMP:FlyBase.::GO:0035006; P:melanization defense response; IMP:FlyBase.::GO:0046844; P:micropyle formation; IMP:FlyBase.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; NAS:FlyBase.::GO:0035313; P:wound healing, spreading of epidermal cells; IMP:FlyBase.
183Q15759    364   MK11_HUMAN Mitogen-activated protein kinase 1...2274e-28     120     30     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
184P35426    303   CDK4_RAT Cyclin-dependent kinase 4 OS=Rattus ...2754e-28     119     29     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:RGD.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045787; P:positive regulation of cell cycle; TAS:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0045793; P:positive regulation of cell size; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010288; P:response to lead ion; IMP:RGD.::GO:0033574; P:response to testosterone stimulus; IDA:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
185P30285    303   CDK4_MOUSE Cyclin-dependent kinase 4 OS=Mus m...2754e-28     119     29     49GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0007165; P:signal transduction; IDA:MGI.
186A1CAF0    380   MPKC_ASPCL Mitogen-activated protein kinase m...3584e-28     120     30     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
187Q3T0N5    366   MK13_BOVIN Mitogen-activated protein kinase 1...3084e-28     120     29     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
188Q9U2Q9    362   GSK3_CAEEL Glycogen synthase kinase-3 OS=Caen...2494e-28     120     26     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0010467; P:gene expression; IMP:WormBase.::GO:0007281; P:germ cell development; IGI:WormBase.::GO:0035188; P:hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
189O04160    468   KSGT_BRANA Shaggy-related protein kinase thet...3695e-28     121     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
190Q6L5F7    582   MPK17_ORYSJ Mitogen-activated protein kinase ...3745e-28     122     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
191Q96287    472   KSG8_ARATH Shaggy-related protein kinase thet...3635e-28     121     25     44GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009741; P:response to brassinosteroid stimulus; IMP:TAIR.
192Q5VP69    501   MPK16_ORYSJ Mitogen-activated protein kinase ...3745e-28     121     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
193P83101    501   GSK3H_DROME Putative glycogen synthase kinase...3115e-28     121     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0048232; P:male gamete generation; IMP:FlyBase.
194Q39025    376   MPK5_ARATH Mitogen-activated protein kinase 5...3095e-28     120     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
195Q9WTU6    423   MK09_MOUSE Mitogen-activated protein kinase 9...2805e-28     120     30     46GO:0044445; C:cytosolic part; ISS:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB.
GO:0031558; P:induction of apoptosis in response to chemical stimulus; IGI:MGI.::GO:0046686; P:response to cadmium ion; IGI:MGI.
196P00546    298   CDK1_YEAST Cyclin-dependent kinase 1 OS=Sacch...3596e-28     118     27     47GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:SGD.::GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0042393; F:histone binding; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051447; P:negative regulation of meiotic cell cycle; IMP:SGD.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:SGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:SGD.::GO:0010571; P:positive regulation of DNA replication involved in S phase; IMP:SGD.::GO:0051446; P:positive regulation of meiotic cell cycle; IDA:SGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:SGD.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:SGD.::GO:0010898; P:positive regulation of triglyceride catabolic process; IMP:SGD.::GO:0010568; P:regulation of budding cell apical bud growth; IMP:SGD.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:SGD.::GO:0010570; P:regulation of filamentous growth; IMP:SGD.
197P18265    483   GSK3A_RAT Glycogen synthase kinase-3 alpha OS...3156e-28     121     25     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
198Q9HGY5    326   PHO85_CANAX Negative regulator of the PHO sys...3626e-28     119     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
199P38615    370   RIM11_YEAST Serine/threonine-protein kinase R...2717e-28     119     28     49GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0030437; P:ascospore formation; IMP:SGD.::GO:0006508; P:proteolysis; IGI:SGD.::GO:0006950; P:response to stress; IGI:SGD.
200Q96TL5    358   HOG1_NEUCR Mitogen-activated protein kinase h...3487e-28     119     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
201Q39010    412   KSG6_ARATH Shaggy-related protein kinase zeta...2527e-28     120     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009742; P:brassinosteroid mediated signaling pathway; IPI:TAIR.::GO:0032880; P:regulation of protein localization; IDA:TAIR.
202P11440    297   CDK1_MOUSE Cyclin-dependent kinase 1 OS=Mus m...3557e-28     118     29     46GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0030544; F:Hsp70 protein binding; IPI:MGI.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IDA:MGI.
203Q00646    323   CDK1_EMENI Cyclin-dependent kinase 1 OS=194 /...3738e-28     118     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
204Q53N72    498   MPK15_ORYSJ Mitogen-activated protein kinase ...2818e-28     120     32     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
205Q9WUI1    364   MK11_MOUSE Mitogen-activated protein kinase 1...2278e-28     119     30     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
206Q2NL51    490   GSK3A_MOUSE Glycogen synthase kinase-3 alpha ...3189e-28     120     26     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0003214; P:cardiac left ventricle morphogenesis; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0071285; P:cellular response to lithium ion; IDA:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IDA:BHF-UCL.::GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; IMP:BHF-UCL.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; IMP:BHF-UCL.::GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:BHF-UCL.::GO:2000467; P:positive regulation of glycogen (starch) synthase activity; IMP:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0003073; P:regulation of systemic arterial blood pressure; IMP:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
207Q3UTQ8    938   CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS...1959e-28     123     35     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
208Q8WQG9    463   JNK1_CAEEL Stress-activated protein kinase jn...2201e-27     120     34     52GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:WormBase.::GO:0008134; F:transcription factor binding; IPI:WormBase.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009408; P:response to heat; IMP:WormBase.::GO:0030050; P:vesicle transport along actin filament; IDA:UniProtKB.
209P31152    587   MK04_HUMAN Mitogen-activated protein kinase 4...3371e-27     121     29     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
210O76039    1030   CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS...1951e-27     122     35     59GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0044294; C:dendritic growth cone; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HGNC.
GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:BHF-UCL.
GO:0001764; P:neuron migration; ISS:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:BHF-UCL.::GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.
211Q9DGE2    361   MK14A_DANRE Mitogen-activated protein kinase ...2761e-27     119     28     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0040016; P:embryonic cleavage; IDA:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0001756; P:somitogenesis; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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