Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL101C
Length:
678
Number of sequences:
5887
Description:
YJL101C GSH1 SGDID:S000003637, Chr X from 236356-234320, Genome Release 64-1-1, reverse complement, Verified ORF, "Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32477    678   GSH1_YEAST Glutamate--cysteine ligase OS=Sacc...6780     1417     100     100GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IDA:SGD.
GO:0006750; P:glutathione biosynthetic process; IDA:SGD.::GO:0046686; P:response to cadmium ion; IDA:SGD.::GO:0042542; P:response to hydrogen peroxide; IMP:SGD.
2Q9HF78    690   GSH1_CANAX Glutamate--cysteine ligase OS=Cand...5722e-176     526     51     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IEA:EC.
GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW.
3P48506    637   GSH1_HUMAN Glutamate--cysteine ligase catalyt...6691e-162     489     42     58GO:0005829; C:cytosol; TAS:Reactome.
GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050662; F:coenzyme binding; IPI:UniProtKB.::GO:0016595; F:glutamate binding; IDA:UniProtKB.::GO:0004357; F:glutamate-cysteine ligase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0045454; P:cell redox homeostasis; IDA:UniProtKB.::GO:0006534; P:cysteine metabolic process; IDA:UniProtKB.::GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050880; P:regulation of blood vessel size; IMP:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
4P19468    637   GSH1_RAT Glutamate--cysteine ligase catalytic...6682e-162     489     42     58GO:0017109; C:glutamate-cysteine ligase complex; IDA:RGD.
GO:0043531; F:ADP binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050662; F:coenzyme binding; ISS:UniProtKB.::GO:0016595; F:glutamate binding; ISS:UniProtKB.::GO:0004357; F:glutamate-cysteine ligase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0045454; P:cell redox homeostasis; ISS:UniProtKB.::GO:0006534; P:cysteine metabolic process; ISS:UniProtKB.::GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050880; P:regulation of blood vessel size; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB.::GO:0051409; P:response to nitrosative stress; IMP:RGD.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
5P97494    637   GSH1_MOUSE Glutamate--cysteine ligase catalyt...6822e-162     488     42     57GO:0005829; C:cytosol; IDA:MGI.::GO:0017109; C:glutamate-cysteine ligase complex; IDA:MGI.
GO:0043531; F:ADP binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050662; F:coenzyme binding; ISS:UniProtKB.::GO:0016595; F:glutamate binding; ISS:UniProtKB.::GO:0004357; F:glutamate-cysteine ligase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0045454; P:cell redox homeostasis; ISS:UniProtKB.::GO:0006534; P:cysteine metabolic process; ISS:UniProtKB.::GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; ISS:UniProtKB.::GO:0019852; P:L-ascorbic acid metabolic process; IMP:MGI.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0050880; P:regulation of blood vessel size; ISS:UniProtKB.::GO:0051900; P:regulation of mitochondrial depolarization; IGI:MGI.::GO:0046685; P:response to arsenic-containing substance; IMP:MGI.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0009410; P:response to xenobiotic stimulus; IMP:MGI.
6Q09768    669   GSH1_SCHPO Glutamate--cysteine ligase OS=Schi...7201e-151     462     41     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0017109; C:glutamate-cysteine ligase complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IMP:PomBase.
GO:0071276; P:cellular response to cadmium ion; IMP:PomBase.::GO:0006750; P:glutathione biosynthetic process; IMP:PomBase.
7Q9NFN6    652   GSH1_ONCVO Glutamate--cysteine ligase OS=Onch...6812e-138     427     40     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IEA:EC.
GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW.
8Q8X0X0    728   GSH1_NEUCR Glutamate--cysteine ligase OS=1257...7062e-138     429     38     54GO:0005737; C:cytoplasm; ISS:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; ISS:RefGenome.
GO:0006750; P:glutathione biosynthetic process; ISS:RefGenome.
9Q54PC2    626   GSH1_DICDI Glutamate--cysteine ligase OS=Dict...6724e-138     425     40     57GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IMP:UniProtKB.
GO:0006750; P:glutathione biosynthetic process; IMP:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
10Q20117    654   GSH1_CAEEL Glutamate--cysteine ligase OS=Caen...6727e-135     418     38     55GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006750; P:glutathione biosynthetic process; IMP:WormBase.::GO:0046685; P:response to arsenic-containing substance; IMP:WormBase.::GO:0009408; P:response to heat; IEP:WormBase.::GO:0009635; P:response to herbicide; IEP:WormBase.
11Q9W3K5    717   GSH1_DROME Glutamate--cysteine ligase OS=Dros...1140.0000000003     67     39     53GO:0017109; C:glutamate-cysteine ligase complex; IPI:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:FlyBase.
GO:0006750; P:glutathione biosynthetic process; NAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
12Q54H38    395   ABHD_DICDI Abhydrolase domain-containing prot...874.6     33.9     32     51GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0004091; F:carboxylesterase activity; IEA:InterPro.
13P37608    691   LCN3_LACLL Lacticin-481/lactococcin-DR transp...359.3     33.1     43     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
GO:0043213; P:bacteriocin transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14B7IKW6    217   TRMB_BACC2 tRNA (guanine-N(7)-)-methyltransfe...899.3     32.3     28     48
GO:0008176; F:tRNA (guanine-N7-)-methyltransferase activity; IEA:EC.
records
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