Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL097W
Length:
217
Number of sequences:
5887
Description:
YJL097W PHS1 SGDID:S000003633, Chr X from 245591-246244, Genome Release 64-1-1, Verified ORF, "Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane, involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40857    217   PHS1_YEAST 3-hydroxyacyl-CoA dehydratase PHS1...2172e-151     426     100     100GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.
GO:0004300; F:enoyl-CoA hydratase activity; IDA:SGD.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0030148; P:sphingolipid biosynthetic process; IMP:SGD.::GO:0007034; P:vacuolar transport; IMP:SGD.
2Q8VZB2    221   PAS2_ARATH 3-hydroxyacyl-CoA dehydratase PAST...2158e-30     115     34     53GO:0005829; C:cytosol; IDA:TAIR.::GO:0009923; C:fatty acid elongase complex; IPI:TAIR.::GO:0016021; C:integral to membrane; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0080023; F:3R-hydroxyacyl-CoA dehydratase activity; IGI:TAIR.
GO:0030154; P:cell differentiation; IMP:TAIR.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048640; P:negative regulation of developmental growth; IMP:TAIR.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:TAIR.::GO:0051302; P:regulation of cell division; IMP:TAIR.::GO:0042761; P:very long-chain fatty acid biosynthetic process; IMP:TAIR.
3Q5ZEJ0    221   PAS2B_ORYSJ 3-hydroxyacyl-CoA dehydratase PAS...2039e-30     115     34     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
4Q7XSZ4    221   PAS2A_ORYSJ 3-hydroxyacyl-CoA dehydratase PAS...2051e-29     115     34     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
5O14346    208   HACD_SCHPO Probable 3-hydroxyacyl-CoA dehydra...2101e-27     109     38     59GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; NAS:PomBase.
6Q9D3B1    254   HACD2_MOUSE 3-hydroxyacyl-CoA dehydratase 2 O...2242e-26     107     32     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
7Q2KIP8    254   HACD2_BOVIN 3-hydroxyacyl-CoA dehydratase 2 O...2234e-26     106     32     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
8Q6Y1H2    254   HACD2_HUMAN 3-hydroxyacyl-CoA dehydratase 2 O...2245e-26     106     32     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
9Q5RBK3    255   HACD2_PONAB 3-hydroxyacyl-CoA dehydratase 2 O...2245e-26     106     32     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
10Q9QY80    281   HACD1_MOUSE 3-hydroxyacyl-CoA dehydratase 1 O...2116e-26     106     34     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
11B0YJ81    288   HACD1_HUMAN 3-hydroxyacyl-CoA dehydratase 1 O...2117e-25     103     33     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0007165; P:signal transduction; NAS:ProtInc.
12Q9N1R5    288   HACD1_SHEEP 3-hydroxyacyl-CoA dehydratase 1 O...2101e-24     102     33     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
13Q4W1W1    249   HACD1_CANFA 3-hydroxyacyl-CoA dehydratase 1 O...2104e-24     100     33     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
14Q9P035    362   HACD3_HUMAN 3-hydroxyacyl-CoA dehydratase 3 O...1530.0000000001     63.5     31     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:ProtInc.::GO:0016601; P:Rac protein signal transduction; NAS:UniProtKB.
15Q7SY06    359   HADC_DANRE 3-hydroxyacyl-CoA dehydratase OS=D...1510.0000000002     63.2     32     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
16Q5NVQ2    364   PTAD1_PONAB 3-hydroxyacyl-CoA dehydratase 3 O...1530.0000000003     62     31     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
17Q5ZM57    362   HACD_CHICK 3-hydroxyacyl-CoA dehydratase OS=G...1540.0000000005     61.6     35     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
18Q8K2C9    362   HACD3_MOUSE 3-hydroxyacyl-CoA dehydratase 3 O...1530.0000000007     61.2     31     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IDA:MGI.::GO:0007254; P:JNK cascade; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
19A7YY55    362   HACD3_BOVIN 3-hydroxyacyl-CoA dehydratase 3 O...1530.0000000009     60.8     31     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
20Q6GNB5    218   HACD_XENLA 3-hydroxyacyl-CoA dehydratase OS=X...1830.000004     49.3     26     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
21A2AKM2    232   HACD4_MOUSE 3-hydroxyacyl-CoA dehydratase 4 O...2100.011     39.3     22     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
22Q5VWC8    232   HACD4_HUMAN 3-hydroxyacyl-CoA dehydratase 4 O...2100.017     38.9     21     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
23P36511    530   UDB15_RAT UDP-glucuronosyltransferase 2B15 OS...1151.9     33.1     23     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.
GO:0015020; F:glucuronosyltransferase activity; IDA:RGD.
GO:0019439; P:aromatic compound catabolic process; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD.
24Q97LQ3    274   UPPP1_CLOAB Undecaprenyl-diphosphatase 1 OS=5...1092.3     32.3     30     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050380; F:undecaprenyl-diphosphatase activity; IEA:EC.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0016311; P:dephosphorylation; IEA:InterPro.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
25Q6C2Z2    1076   BST1A_YARLI GPI inositol-deacylase A OS=lipol...1108     31.2     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IEA:InterPro.
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0006505; P:GPI anchor metabolic process; IEA:InterPro.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
records
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