Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL095W
Length:
1478
Number of sequences:
5887
Description:
YJL095W BCK1 SGDID:S000003631, Chr X from 247255-251691, Genome Release 64-1-1, Verified ORF, "Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
901P49101    513   CDPK2_MAIZE Calcium-dependent protein kinase ...2702e-22     106     27     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
902Q55BN8    418   NEK2_DICDI Probable serine/threonine-protein ...2732e-22     105     28     51GO:0005813; C:centrosome; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
GO:0007098; P:centrosome cycle; IMP:dictyBase.
903Q683C9    282   AUR2_ARATH Serine/threonine-protein kinase Au...2642e-22     104     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IDA:TAIR.
904Q9QYZ6    504   SMK2A_MOUSE Sperm motility kinase 2A OS=Mus m...2602e-22     106     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
905P41241    450   CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus ...2622e-22     105     30     53GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:HGNC.
GO:0005524; F:ATP binding; TAS:HGNC.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; TAS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0050863; P:regulation of T cell activation; TAS:HGNC.
906Q12152    901   YP150_YEAST Putative serine/threonine-protein...2652e-22     108     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
907P40376    512   KAPB_SCHPO cAMP-dependent protein kinase cata...2032e-22     106     33     54GO:0005952; C:cAMP-dependent protein kinase complex; TAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IGI:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0001315; P:age-dependent response to reactive oxygen species; IMP:PomBase.::GO:0019933; P:cAMP-mediated signaling; IC:PomBase.::GO:0001300; P:chronological cell aging; IGI:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IMP:PomBase.::GO:0031138; P:negative regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0006110; P:regulation of glycolysis; NAS:PomBase.
908Q9SIQ7    582   CDPKO_ARATH Calcium-dependent protein kinase ...3082e-22     107     27     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
909A3LN91    385   HOG1_PICST Mitogen-activated protein kinase H...2962e-22     105     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
910O77708    533   KCC2D_RABIT Calcium/calmodulin-dependent prot...2872e-22     106     28     47GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
911P10102    672   KPCA_RABIT Protein kinase C alpha type OS=Ory...2032e-22     107     32     53GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
912P51955    445   NEK2_HUMAN Serine/threonine-protein kinase Ne...2782e-22     105     30     47GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051299; P:centrosome separation; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB.
913A8X0C4    649   PAR4_CAEBR Serine/threonine-protein kinase pa...3602e-22     107     28     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
914Q871M9    545   BUR1_NEUCR Serine/threonine-protein kinase bu...2162e-22     106     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
915P50750    372   CDK9_HUMAN Cyclin-dependent kinase 9 OS=Homo ...2062e-22     105     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0008023; C:transcription elongation factor complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0071345; P:cellular response to cytokine stimulus; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006282; P:regulation of DNA repair; IDA:UniProtKB.::GO:0031056; P:regulation of histone modification; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0043111; P:replication fork arrest; IDA:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:ProtInc.::GO:0016032; P:viral reproduction; TAS:Reactome.
916Q753D9    726   PKH3_ASHGO Serine/threonine-protein kinase PK...2742e-22     107     26     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
917Q6C842    706   BUR1_YARLI Serine/threonine-protein kinase BU...2442e-22     107     30     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
918P29618    294   CDKA1_ORYSJ Cyclin-dependent kinase A-1 OS=Or...2912e-22     103     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
919Q6P0Q8    1798   MAST2_HUMAN Microtubule-associated serine/thr...2422e-22     108     29     50GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045075; P:regulation of interleukin-12 biosynthetic process; ISS:UniProtKB.::GO:0048515; P:spermatid differentiation; ISS:UniProtKB.
920Q54QB1    369   ERK2_DICDI Extracellular signal-regulated kin...2962e-22     104     29     50GO:0005829; C:cytosol; TAS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; IGI:dictyBase.
921Q10452    387   GSK3_SCHPO Protein kinase gsk3 OS=Schizosacch...3122e-22     105     28     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:UniProtKB.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051984; P:positive regulation of chromosome segregation; IMP:UniProtKB.::GO:0071775; P:regulation of cell cycle cytokinesis; IGI:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
922O15021    2626   MAST4_HUMAN Microtubule-associated serine/thr...2502e-22     108     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
923P10829    697   KPCG_RABIT Protein kinase C gamma type OS=Ory...2062e-22     107     31     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.
924Q641Z4    372   CDK9_RAT Cyclin-dependent kinase 9 OS=Rattus ...2062e-22     104     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
925Q99J95    372   CDK9_MOUSE Cyclin-dependent kinase 9 OS=Mus m...2062e-22     104     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0008024; C:positive transcription elongation factor complex b; TAS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.::GO:0017069; F:snRNA binding; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
926P53670    638   LIMK2_RAT LIM domain kinase 2 OS=Rattus norve...3033e-22     107     26     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007286; P:spermatid development; TAS:RGD.
927Q5EAB2    372   CDK9_BOVIN Cyclin-dependent kinase 9 OS=Bos t...2063e-22     104     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
928P53671    638   LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapie...3033e-22     107     26     45GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042325; P:regulation of phosphorylation; IEA:InterPro.
929Q811L6    2618   MAST4_MOUSE Microtubule-associated serine/thr...2173e-22     108     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
930P04409    672   KPCA_BOVIN Protein kinase C alpha type OS=Bos...2053e-22     107     33     53GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
931P15791    533   KCC2D_RAT Calcium/calmodulin-dependent protei...2873e-22     106     28     47GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
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