rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | Q99558 | 947 | M3K14_HUMAN Mitogen-activated protein kinase ... | 359 | 1e-25 | 119 | 30 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004704; F:NF-kappaB-inducing kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0006955; P:immune response; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 512 | P90980 | 682 | KPC2_CAEEL Protein kinase C-like 2 OS=Caenorh... | 202 | 1e-25 | 118 | 34 | 58 | GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0043005; C:neuron projection; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 513 | Q55CE0 | 677 | MKCF_DICDI Probable serine/threonine-protein ... | 264 | 1e-25 | 117 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 514 | Q0V7M1 | 424 | KPSH1_BOVIN Serine/threonine-protein kinase H... | 270 | 1e-25 | 115 | 30 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 515 | A4IGM9 | 360 | AURKB_XENTR Aurora kinase B OS=Xenopus tropic... | 268 | 2e-25 | 114 | 29 | 47 | GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0032133; C:chromosome passenger complex; ISS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 516 | Q12236 | 1081 | PKH2_YEAST Serine/threonine-protein kinase PK... | 293 | 2e-25 | 118 | 28 | 51 | GO:0032126; C:eisosome; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD. | 517 | P00517 | 351 | KAPCA_BOVIN cAMP-dependent protein kinase cat... | 221 | 2e-25 | 114 | 33 | 57 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; ISS:AgBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001707; P:mesoderm formation; ISS:AgBase. | 518 | Q01919 | 800 | KIN4_YEAST Serine/threonine-protein kinase KI... | 289 | 2e-25 | 118 | 30 | 49 | GO:0005938; C:cell cortex; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:SGD. | | | | | | | | | | GO:0031578; P:mitotic cell cycle spindle orientation checkpoint; IMP:SGD. | 519 | Q91757 | 420 | GSK3B_XENLA Glycogen synthase kinase-3 beta O... | 218 | 2e-25 | 115 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 520 | P38070 | 525 | YPK3_YEAST AGC kinase YPK3 OS=Saccharomyces c... | 280 | 2e-25 | 116 | 28 | 51 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 521 | Q2QYM3 | 439 | CIPKE_ORYSJ CBL-interacting protein kinase 14... | 218 | 2e-25 | 115 | 33 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 522 | Q3TZA2 | 342 | CDKL4_MOUSE Cyclin-dependent kinase-like 4 OS... | 288 | 2e-25 | 114 | 27 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 523 | Q8MJ44 | 350 | KAPCA_CANFA cAMP-dependent protein kinase cat... | 221 | 2e-25 | 114 | 33 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 524 | Q9SLI2 | 612 | NEK1_ARATH Serine/threonine-protein kinase Ne... | 265 | 2e-25 | 117 | 30 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 525 | Q9CAU7 | 606 | NEK2_ARATH Serine/threonine-protein kinase Ne... | 266 | 2e-25 | 117 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 526 | Q8TDC3 | 778 | BRSK1_HUMAN Serine/threonine-protein kinase B... | 262 | 2e-25 | 117 | 29 | 52 | GO:0030054; C:cell junction; IDA:HPA.::GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IC:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0051298; P:centrosome duplication; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0007269; P:neurotransmitter secretion; ISS:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB. | 527 | Q96WV9 | 591 | CDK9_SCHPO Probable cyclin-dependent kinase 9... | 307 | 2e-25 | 116 | 28 | 49 | GO:0070693; C:P-TEFb-cap methyltransferase complex; IDA:PomBase.::GO:0008024; C:positive transcription elongation factor complex b; NAS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:PomBase. | | | | | | | | | | GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:PomBase.::GO:0034243; P:regulation of transcription elongation from RNA polymerase II promoter; IMP:PomBase.::GO:0006360; P:transcription from RNA polymerase I promoter; IGI:PomBase. | 528 | Q9NRP7 | 1315 | STK36_HUMAN Serine/threonine-protein kinase 3... | 265 | 2e-25 | 118 | 32 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0000287; F:magnesium ion binding; IC:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB. | 529 | Q9WUL6 | 942 | M3K14_MOUSE Mitogen-activated protein kinase ... | 267 | 2e-25 | 118 | 35 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004704; F:NF-kappaB-inducing kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB. | 530 | Q02779 | 954 | M3K10_HUMAN Mitogen-activated protein kinase ... | 269 | 2e-25 | 118 | 30 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB. | 531 | P11801 | 424 | KPSH1_HUMAN Serine/threonine-protein kinase H... | 270 | 2e-25 | 115 | 30 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB. | | | | | | | | | | | 532 | P22612 | 351 | KAPCG_HUMAN cAMP-dependent protein kinase cat... | 201 | 2e-25 | 114 | 36 | 57 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0008584; P:male gonad development; TAS:ProtInc.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 533 | Q63562 | 467 | M3K8_RAT Mitogen-activated protein kinase kin... | 258 | 2e-25 | 115 | 33 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:InterPro. | 534 | Q6DE08 | 361 | AUKBA_XENLA Aurora kinase B-A OS=Xenopus laev... | 268 | 2e-25 | 114 | 29 | 47 | | | | | | | | | | | | | | | | | | | | | | 535 | Q9MZD9 | 351 | KAPCA_SHEEP cAMP-dependent protein kinase cat... | 221 | 2e-25 | 114 | 33 | 56 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 536 | B4KYX8 | 778 | PLK4_DROMO Serine/threonine-protein kinase PL... | 264 | 2e-25 | 117 | 31 | 50 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 537 | Q54H46 | 642 | DRKA_DICDI Probable serine/threonine-protein ... | 261 | 2e-25 | 117 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 538 | Q8WNU8 | 637 | NEK11_MACFA Serine/threonine-protein kinase N... | 297 | 2e-25 | 117 | 31 | 51 | GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0031573; P:intra-S DNA damage checkpoint; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 539 | Q86AD7 | 392 | MYLKB_DICDI Probable myosin light chain kinas... | 332 | 2e-25 | 114 | 26 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | GO:0007165; P:signal transduction; ISS:dictyBase. | 540 | P68182 | 351 | KAPCB_RAT cAMP-dependent protein kinase catal... | 201 | 3e-25 | 114 | 33 | 57 | GO:0005952; C:cAMP-dependent protein kinase complex; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; IC:RGD. | | | | | | | | | | GO:0051447; P:negative regulation of meiotic cell cycle; IDA:RGD. | 541 | P68181 | 351 | KAPCB_MOUSE cAMP-dependent protein kinase cat... | 201 | 3e-25 | 114 | 33 | 57 | GO:0005952; C:cAMP-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:UniProtKB. |